Eumetopias jubatus (Steller sea lion): 114196399
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Entry
114196399 CDS
T07240
Symbol
JAK3
Name
(RefSeq) tyrosine-protein kinase JAK3 isoform X1
KO
K11218
Janus kinase 3 [EC:
2.7.10.2
]
Organism
eju
Eumetopias jubatus (Steller sea lion)
Pathway
eju04062
Chemokine signaling pathway
eju04151
PI3K-Akt signaling pathway
eju04217
Necroptosis
eju04550
Signaling pathways regulating pluripotency of stem cells
eju04630
JAK-STAT signaling pathway
eju04658
Th1 and Th2 cell differentiation
eju04659
Th17 cell differentiation
eju05161
Hepatitis B
eju05162
Measles
eju05166
Human T-cell leukemia virus 1 infection
eju05169
Epstein-Barr virus infection
eju05200
Pathways in cancer
eju05203
Viral carcinogenesis
eju05223
Non-small cell lung cancer
eju05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
eju00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
114196399 (JAK3)
04151 PI3K-Akt signaling pathway
114196399 (JAK3)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
114196399 (JAK3)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
114196399 (JAK3)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
114196399 (JAK3)
04659 Th17 cell differentiation
114196399 (JAK3)
04062 Chemokine signaling pathway
114196399 (JAK3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
114196399 (JAK3)
05203 Viral carcinogenesis
114196399 (JAK3)
09162 Cancer: specific types
05223 Non-small cell lung cancer
114196399 (JAK3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
114196399 (JAK3)
05161 Hepatitis B
114196399 (JAK3)
05162 Measles
114196399 (JAK3)
05169 Epstein-Barr virus infection
114196399 (JAK3)
09163 Immune disease
05340 Primary immunodeficiency
114196399 (JAK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
eju01001
]
114196399 (JAK3)
Enzymes [BR:
eju01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
114196399 (JAK3)
Protein kinases [BR:
eju01001
]
Non-receptor tyrosine kinases
JAK family [OT]
114196399 (JAK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
SH2_1
FERM_F1
Jak1_Phl
Kdo
ABC1
FERM_C_FAK1
FERM_M
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
114196399
NCBI-ProteinID:
XP_027942849
LinkDB
All DBs
Position
Unknown
AA seq
1133 aa
AA seq
DB search
MAPPSEETPLIPQRSCSLSSSEAGALHVLLPPRGPGPPQRLSFSFGDHSAEELCVWAAKA
SGILPVYHSLFALATEDLSCWFPPSHVFSVEDSGTQVLVYRLRLLPFPNSFYFPNWFGLE
KCHRFGLRKDLASAILDLPVLEHLFAQHRNDLVSGHLPVGLSLKEQGECLSLAVLDLARM
AHEQAQQPEELLKTVSYKVCLPPDLRDLIQGLSFVTRKRIRRTVRRALRRVTACQADRHS
LMAKYIMDLERLDPARAVETFLVSLPGAAGGLDVQGLLRVAGDTGIAWSPGGQEALQPFC
DFPEIVDISIKQAPRVGPAGEHRLVTVTRTDNQILEAEFPGLPAALSFVALVDGYFRLTS
DSRHFFCKEVAPPRLLEEVAEQCHGPITLDFAINKLKTGGSLPGSYVLRRSPQDFDCFLL
TVCVQTPLGPDYKGCLIRCDPTGTFSLAGLGRPHSSLRELLAACWDGGLHVDGVALNLTF
CCTPKPKEKSNLIVVRRGCSTPTSSPVQPQSQYQLNQMTFHKIPADSLEWHENLGHGSFT
KIYRGCRHEVVEGEARETEVLLKVMDAKHKNCMESFLEAASLMSQVSYQHLVLLHGVCMA
GDSIMVQEFVHLGALDTYLRKSGHLVPASWKLQVIKQLAYALNYLEDKGLPHGNVSARKV
LLAREGADGNLPFIKLSDPGVSPSVLSREMLTDRIPWVAPECLQEARTLGLEADKWGFGA
TVWEVFSGIPMPISTLDPAKKLQFYEERQQLPAPKWMELAILIQQCMAYEPGQRPSFRAI
IRDLNSLITSDYELLSDPTPGALAPRDGLWNGAQLYAYQDPTIFEERHLKYISQLGKGNF
GSVELCRYDPLGDNTGALVAVKQLQHSGPDQQRDFRREIQILKALHSDFIVKYRGVSYGP
GRQSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYASQICKGMEYLGSRRCVHRDLAAR
NILVESETHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWWGPRPGPPLLSTTLDPTSLP
LPYAPESLSDNIFSRQSDVWSFGVVLYELFTYGNKSCSPSAEFLRMMACDGDVPALCCLL
ELLAEGQRLPAPPACPGEVHELMKLCWAPSPQDRPTFSALGPQLDALWSASQG
NT seq
3402 nt
NT seq
+upstream
nt +downstream
nt
atggcacctccaagcgaggagacacccctgattcctcagcgttcctgcagcctctcgtct
tcagaagctggtgccctgcacgtgctgctgccccctcggggccctggacccccacaacgc
ctatctttctcctttggggatcattcagctgaagagctgtgtgtttgggctgctaaggcc
agtggcatcctgcctgtgtaccactccctctttgctctggccacggaggatctgtcctgc
tggttccccccaagccacgtcttctccgtggaggactcgggcacccaagtcctggtctac
aggctccggcttctccccttccccaacagcttttacttccccaactggtttgggctagag
aagtgccaccgctttgggctacgaaaggacttggccagcgccatccttgacctaccagtc
ctggagcacctcttcgcccagcaccggaatgacctggtgagtggccacctccctgtgggc
ctcagtctcaaggagcagggtgaatgtctcagcctggcggtgctggacctggcccggatg
gctcacgagcaggctcagcagcctgaggaactgctgaaaactgtcagctacaaggtctgc
ctgccccccgacctgcgcgacctgatccagggcctgagcttcgtgacgcggaagcgcatc
cgcaggactgtgcgcagggccctgcgccgcgtgaccgcctgccaggctgacaggcactcg
ctcatggccaagtacatcatggacctggagaggctcgacccggccagggcggtcgagacc
ttcctcgtgagcctccccggggctgctggtggtctggatgtgcaggggctgctccgagtg
gctggtgacaccggcattgcctggagtccaggaggacaagaggccctccagcccttctgc
gactttccagaaattgtggacatcagcatcaagcaggctccgcgtgttggcccggccggg
gagcaccgcctggtcaccgtcacgaggacagacaaccagatcctggaggccgagttcccg
gggctgcccgccgcgttgtccttcgtggcgctcgtcgacggctacttcaggctgacctcc
gactccaggcacttcttttgcaaggaggttgcgccgccgcggctgctggaggaggtggcc
gagcagtgccacggccccatcaccctggattttgccatcaacaagctcaagactgggggc
tcacttcccggctcctacgttctccgccgcagtccccaggattttgattgcttcctcctc
actgtctgtgtccagacccccctgggtcctgattataagggctgcctcatccggtgtgac
cccacgggaaccttctccctggctggccttggccgtccccatagcagtctccgagagctc
ttggcagcctgctgggatggcgggctgcacgtggacggggttgcgctgaacctcaccttc
tgctgcacccccaaacccaaagaaaagtccaacctgattgtggtgcggaggggttgcagc
acacccacttcatcccctgttcagccccaatcccaataccagctgaatcagatgacgttt
cacaagatccctgctgacagcctggagtggcatgagaacctgggtcacgggtccttcacc
aagatataccgaggttgtcgccacgaggtcgtggagggggaggcccgggagacggaggtg
ctgctcaaagtgatggatgccaaacataaaaactgcatggagtcatttctggaagcagcg
agtttgatgagccaagtgtcataccagcatctcgtgttgctccatggcgtgtgcatggcc
ggagacagtatcatggtacaggaatttgtacacctgggagcgctggacacctacctgcgc
aagtctggccacctggtgccagccagctggaagctgcaggtgatcaaacagctggcctat
gccctcaactatctggaagacaaaggcctcccccatggcaatgtctcagcccggaaggtg
ctcctggctcgcgaaggggctgatgggaacctgcccttcatcaagctgagtgatcctggt
gtcagcccctctgtgctaagccgggagatgctcactgacaggatcccctgggtggccccc
gagtgtctccaggaggcccggacactcggcttggaagctgacaagtggggttttggtgcc
acagtctgggaggtgttcagtgggatcccgatgcccatcagcaccctggatcccgccaag
aagctccagttttacgaggagcggcagcagctgcctgcccccaagtggatggagctggcc
atactgatccagcagtgcatggcctatgagccaggccagagaccctccttccgtgccatc
atccgtgacctgaacagcctcatcacttcagattatgagctcctctcagaccccacgccc
ggtgccttggcgccccgtgatgggctgtggaatggcgcccagctctacgcctaccaggac
cctaccatttttgaggagagacacctcaagtacatctcacagctgggcaagggcaacttc
ggcagcgtggaactgtgccgttatgaccctctgggtgacaacacgggcgccctagtggca
gtgaagcagctgcagcacagcgggccagaccagcagagggacttccggagggagatccag
atcctcaaagccctccacagcgacttcattgtcaagtaccgtggtgtcagctatggccca
ggccgccagagcctgcggctggtgatggagtacctgcccagcggctgcctgcgcgacttc
ctacagcggcaccgcgcgcgcctcgacgccagccgcctgctcctctacgcctcgcagatc
tgcaagggcatggagtacctgggctcccgccgctgcgtgcaccgcgacctggctgcgcgt
aacatcctggtggagagcgagacgcacgtcaagatcgccgactttggcctcgccaagctg
ctgccgctcgacaaagactactacgtggtccgcgagcccggccagagccccatcttctgg
tggggaccccgccctggcccacctctcctctccactactctggaccctacctcgctccca
cttccgtacgccccggagtccctctctgacaacatcttctcgcgccagtccgacgtctgg
agcttcggggtcgtcctgtacgagcttttcacctacggcaacaagagttgcagcccctca
gccgagttcctgcggatgatggcatgtgatggagatgtcccggccctctgctgcctcctg
gagctgctggctgagggccagaggctgcccgcgcctcctgcctgccctggtgaggttcat
gagctcatgaagctgtgctgggcccctagcccgcaagaccggccaacattcagtgccctg
ggcccccagctggatgcactatggagtgcaagccagggctag
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