Eumetopias jubatus (Steller sea lion): 114199416 Help Entry 114199416         CDS       T07240                                  Symbol ADCY5 Name (RefSeq) adenylate cyclase type 5   KO K08045   adenylate cyclase 5 [EC:4.6.1.1] Organism eju  Eumetopias jubatus (Steller sea lion) Pathway eju00230   Purine metabolism eju01100   Metabolic pathways eju01522   Endocrine resistance eju04015   Rap1 signaling pathway eju04022   cGMP-PKG signaling pathway eju04024   cAMP signaling pathway eju04062   Chemokine signaling pathway eju04072   Phospholipase D signaling pathway eju04114   Oocyte meiosis eju04211   Longevity regulating pathway eju04213   Longevity regulating pathway - multiple species eju04261   Adrenergic signaling in cardiomyocytes eju04270   Vascular smooth muscle contraction eju04371   Apelin signaling pathway eju04540   Gap junction eju04611   Platelet activation eju04713   Circadian entrainment eju04714   Thermogenesis eju04723   Retrograde endocannabinoid signaling eju04724   Glutamatergic synapse eju04725   Cholinergic synapse eju04726   Serotonergic synapse eju04727   GABAergic synapse eju04728   Dopaminergic synapse eju04750   Inflammatory mediator regulation of TRP channels eju04911   Insulin secretion eju04912   GnRH signaling pathway eju04913   Ovarian steroidogenesis eju04914   Progesterone-mediated oocyte maturation eju04915   Estrogen signaling pathway eju04916   Melanogenesis eju04918   Thyroid hormone synthesis eju04921   Oxytocin signaling pathway eju04923   Regulation of lipolysis in adipocytes eju04924   Renin secretion eju04925   Aldosterone synthesis and secretion eju04926   Relaxin signaling pathway eju04927   Cortisol synthesis and secretion eju04928   Parathyroid hormone synthesis, secretion and action eju04934   Cushing syndrome eju04935   Growth hormone synthesis, secretion and action eju04970   Salivary secretion eju04971   Gastric acid secretion eju04972   Pancreatic secretion eju04976   Bile secretion eju05012   Parkinson disease eju05030   Cocaine addiction eju05031   Amphetamine addiction eju05032   Morphine addiction eju05034   Alcoholism eju05163   Human cytomegalovirus infection eju05166   Human T-cell leukemia virus 1 infection eju05200   Pathways in cancer eju05207   Chemical carcinogenesis - receptor activation eju05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:eju00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     114199416 (ADCY5)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     114199416 (ADCY5)    04371 Apelin signaling pathway     114199416 (ADCY5)    04072 Phospholipase D signaling pathway     114199416 (ADCY5)    04024 cAMP signaling pathway     114199416 (ADCY5)    04022 cGMP-PKG signaling pathway     114199416 (ADCY5)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     114199416 (ADCY5)   09144 Cellular community - eukaryotes    04540 Gap junction     114199416 (ADCY5)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     114199416 (ADCY5)    04062 Chemokine signaling pathway     114199416 (ADCY5)   09152 Endocrine system    04911 Insulin secretion     114199416 (ADCY5)    04923 Regulation of lipolysis in adipocytes     114199416 (ADCY5)    04912 GnRH signaling pathway     114199416 (ADCY5)    04913 Ovarian steroidogenesis     114199416 (ADCY5)    04915 Estrogen signaling pathway     114199416 (ADCY5)    04914 Progesterone-mediated oocyte maturation     114199416 (ADCY5)    04921 Oxytocin signaling pathway     114199416 (ADCY5)    04926 Relaxin signaling pathway     114199416 (ADCY5)    04935 Growth hormone synthesis, secretion and action     114199416 (ADCY5)    04918 Thyroid hormone synthesis     114199416 (ADCY5)    04928 Parathyroid hormone synthesis, secretion and action     114199416 (ADCY5)    04916 Melanogenesis     114199416 (ADCY5)    04924 Renin secretion     114199416 (ADCY5)    04925 Aldosterone synthesis and secretion     114199416 (ADCY5)    04927 Cortisol synthesis and secretion     114199416 (ADCY5)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     114199416 (ADCY5)    04270 Vascular smooth muscle contraction     114199416 (ADCY5)   09154 Digestive system    04970 Salivary secretion     114199416 (ADCY5)    04971 Gastric acid secretion     114199416 (ADCY5)    04972 Pancreatic secretion     114199416 (ADCY5)    04976 Bile secretion     114199416 (ADCY5)   09156 Nervous system    04724 Glutamatergic synapse     114199416 (ADCY5)    04727 GABAergic synapse     114199416 (ADCY5)    04725 Cholinergic synapse     114199416 (ADCY5)    04728 Dopaminergic synapse     114199416 (ADCY5)    04726 Serotonergic synapse     114199416 (ADCY5)    04723 Retrograde endocannabinoid signaling     114199416 (ADCY5)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     114199416 (ADCY5)   09149 Aging    04211 Longevity regulating pathway     114199416 (ADCY5)    04213 Longevity regulating pathway - multiple species     114199416 (ADCY5)   09159 Environmental adaptation    04713 Circadian entrainment     114199416 (ADCY5)    04714 Thermogenesis     114199416 (ADCY5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     114199416 (ADCY5)    05207 Chemical carcinogenesis - receptor activation     114199416 (ADCY5)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     114199416 (ADCY5)    05163 Human cytomegalovirus infection     114199416 (ADCY5)   09164 Neurodegenerative disease    05012 Parkinson disease     114199416 (ADCY5)   09165 Substance dependence    05030 Cocaine addiction     114199416 (ADCY5)    05031 Amphetamine addiction     114199416 (ADCY5)    05032 Morphine addiction     114199416 (ADCY5)    05034 Alcoholism     114199416 (ADCY5)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     114199416 (ADCY5)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     114199416 (ADCY5)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     114199416 (ADCY5) Enzymes [BR:eju01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      114199416 (ADCY5) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AC_N Guanylate_cyc Adcy_cons_dom TBK1_ULD GBR2_CC PEN-2 Motif Other DBs NCBI-GeneID:  114199416 NCBI-ProteinID:  XP_027947107 LinkDB All DBs Position Unknown AA seq 1259 aa AA seqDB search MSGSKSVSPPGYAAQTAAAPASRGGPEHRSAWGEADSRANGYPHAPGGSTRGCTKKPGGA VTPQQQQRLANRWRSDDDDDPPLSGDDPLAGGFGFSFRSKSAWQERGGDDCGRGSRRQRR GAAGGGSTRAPPAGGGAGSAAAAAAAGGTEVRPRSVELGLEERRGKGRAVDELEAGAVEG DEGAGDGGSSAESGAGPGAVLSLGACCLALLQIFRSKKFPSDKLERLYQRYFFRLNQSSL TMLMAVLVLVCLVMLAFHAARPPLQLPYLAVLAAAVGVILVMAVLCNRAAFHQDHMGLAC YALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLSALHL AIALRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARLHSQ RENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTSLA SQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGM DMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAG RIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAKMNRQ RTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESANPEDEVDEFLGR AIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFVQITI VPHSVFMLSFYLTCFLLLALVVFVSVVYSCVKLFPAPLQTLSRKIVRSKMNSTLVGVFTI TLVFLSAFVNMFMCNSKDLFGCLADEHNISTGQVNACHVVESAANYSLGDERGFCSSPWP NCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELTYVLIVEVPRVTLFDNADLLV TANAIDFNNNGTSQCPEHATKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWKLQA TEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSE FYVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTYDK VGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNT VNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPLS NT seq 3780 nt NT seq  +upstreamnt  +downstreamnt atgtccggctccaaaagcgtgagccccccgggctacgcggcgcagacagcggccgcgccg gcgtcccggggaggcccggaacaccgctcggcgtggggggaagcggattcccgcgccaat ggctacccccacgcccctgggggttcgacccgcggctgcaccaagaaacccgggggggcg gtgaccccgcagcagcagcagcgcctggccaaccgctggcgcagcgacgacgacgacgat cctccgctgagtggcgacgaccccctggccgggggcttcggcttcagcttccgctccaag tcggcttggcaggagcgcggcggcgacgactgcggtcgcggcagccgccggcagcgccgg ggcgcggccggcgggggcagcacccgggcgccccctgcgggtggcggtgccggctcggcg gcggcggccgcggcggcgggcgggacggaggtgcgccctcgctcggtggagctgggcctg gaggagcggcggggcaagggccgcgcggtggacgagctggaggccggcgccgtcgagggc gacgaaggggcgggggatggcggcagctcggcagaatcaggcgcggggcccggcgcagtg ctgtcgctgggtgcctgctgcttggcgctgctgcagatattccgctccaagaagttcccg tccgacaagctggagcggctgtaccagcgctacttcttccgtctgaaccagagtagcctc accatgctcatggccgtgctggtgctcgtgtgcctcgtcatgctggccttccacgcggcg cggcccccgctccagctgccctacctggcagtgctggcggctgcggtaggtgtcatcctc gtcatggctgtgctctgcaaccgcgccgccttccaccaggaccacatgggcctggcctgc tacgcgctcatcgccgtggtgctggccgtgcaggtggtgggcctgctgctgccccagccg cgcagcgcctccgagggcatctggtggaccgtgttcttcatctacaccatctacacgttg ctgcctgtgcgcatgcgggccgcggtactcagcggagtgctcctgtcggccctccacctg gccatcgccttgcgcaccaacgcccaggaccagttcctgctcaagcagcttgtctccaat gtcctcattttctcctgcaccaacatcgtgggtgtctgcacccactacccagctgaggtc tcccagagacaggccttccaggagacccgggagtgcatccaggcacgactccactcacaa cgggagaaccagcaacaggagcggctcctgctgtctgtcctcccccgtcatgttgccatg gagatgaaagcagacatcaatgccaagcaggaggatatgatgttccataagatttacatc cagaaacatgacaacgtgagcatcctgtttgctgacatcgagggcttcaccagcctggca tcccagtgcactgcccaggagctggtcatgaccctcaacgagctctttgcccgcttcgac aagctggccgcggagaaccactgtttacgtattaagatcctgggggattgttattactgt gtctctgggctgccggaagcgagggctgaccacgcccactgctgcgtggagatgggcatg gacatgattgaggccatctcgttggtccgggaggtgacaggggtgaacgtgaacatgcgc gtgggaattcacagcgggcgagtacactgcggtgtccttggtctcaggaagtggcagttc gacgtctggtctaatgacgtcacgctggccaaccacatggaagctggaggcaaggcaggg cgcatccacatcaccaaggccacactcaactacctgaacggtgactacgaggtggagcca ggctgcgggggcgagcgcaacgcctacctcaaggagcacagtatcgagaccttcctcatc ctgcgctgcacccagaagcggaaagaagaaaaggccatgatcgccaagatgaatcgccag agaaccaactccattgggcacaacccgccccactggggtgccgagcgtcccttctacaac cacctagggggcaaccaggtgtccaaggagatgaagcggatgggctttgaagaccccaag gacaagaacgcccaggaaagcgcaaaccctgaggatgaagtggacgaatttctgggccgt gccattgacgccaggagcatcgacaggctgcggtctgagcacgtccgcaagttcctcttg accttcagggagcctgacttagagaagaagtactccaagcaggtggatgaccgattcggt gcctacgtggcatgtgcctcgcttgtcttcctcttcatctgctttgtccagatcaccatc gtgccccactccgtgttcatgttgagtttctacctgacctgtttcctgctgctggcgttg gtggtatttgtgtccgtggtctattcctgcgtgaagctcttcccagcccccctgcagacc ctctccaggaagattgtgcggtccaagatgaatagcactctggtcggagtgttcaccatc accctagtgttcctgtcggctttcgtcaacatgttcatgtgtaactccaaggacctgttc ggctgcctggcagatgagcacaacatcagcaccggccaggtcaacgcgtgccacgtggtg gagtcagccgccaactacagcctgggggatgagcggggcttctgcagcagtccgtggccc aactgcaacttccctgagtacttcacctacagcgtgctgctcagcctgctggcctgctcc gtgttcctgcagatcagctgcattgggaagctggtgctcatgctggccattgagctcaca tatgtgctcatcgtcgaggtgccccgtgtcacgctctttgacaatgctgacctgctggtc actgccaacgccatagacttcaacaacaacgggacctcccagtgccctgagcatgcgacc aaggtggcactgaaggtggtgacgcccatcatcatctccgtctttgtgctggccctatac ctgcatgcccagcaggtggagtccaccgcccgcctggacttcctctggaaactgcaggcc acggaggagaaggaggagatggaggagctgcaggcctacaacaggcggctgctgcacaac atcctgcccaaggacgtggccgcccacttcctggcccgcgagcgacgcaacgacgagctc tactaccagtcgtgcgagtgcgtggccgtcatgtttgcctccatcgccaacttctccgag ttctacgtggagctggaagccaacaacgagggcgtcgagtgcctgcggctgctcaacgag atcatcgccgactttgacgagatcatcagcgaggatcggttcaggcagctggaaaagatc aagaccattggcagcacctacatggccgcctcaggcctcaatgattccacgtacgacaag gtgggcaagacccacatcaaagccctggccgactttgccatgaagctcatggatcaaatg aagtacatcaatgaacactccttcaacaacttccagatgaagatcgggctcaacatcggc cccgtggtggccggggtgatcggggctcgcaagcctcagtacgacatctggggcaatacg gtgaacgtggccagccgcatggatagcaccggtgtgcctgaccgcatccaggtcaccacg gacatgtaccaggtgctggctgccaacacataccagctggagtgcaggggtgtggtcaag gtcaagggcaaaggcgagatgatgacctacttcctcaacggggggcccccgctcagttag

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