KEGG   Eumetopias jubatus (Steller sea lion): 114210281
Entry
114210281         CDS       T07240                                 
Name
(RefSeq) phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN-like
  KO
K01110  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
Organism
eju  Eumetopias jubatus (Steller sea lion)
Pathway
eju00562  Inositol phosphate metabolism
eju01100  Metabolic pathways
eju01521  EGFR tyrosine kinase inhibitor resistance
eju04068  FoxO signaling pathway
eju04070  Phosphatidylinositol signaling system
eju04071  Sphingolipid signaling pathway
eju04115  p53 signaling pathway
eju04140  Autophagy - animal
eju04150  mTOR signaling pathway
eju04151  PI3K-Akt signaling pathway
eju04218  Cellular senescence
eju04510  Focal adhesion
eju04931  Insulin resistance
eju05165  Human papillomavirus infection
eju05166  Human T-cell leukemia virus 1 infection
eju05200  Pathways in cancer
eju05206  MicroRNAs in cancer
eju05208  Chemical carcinogenesis - reactive oxygen species
eju05213  Endometrial cancer
eju05214  Glioma
eju05215  Prostate cancer
eju05218  Melanoma
eju05222  Small cell lung cancer
eju05224  Breast cancer
eju05225  Hepatocellular carcinoma
eju05230  Central carbon metabolism in cancer
eju05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
eju05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:eju00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    114210281
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    114210281
   04070 Phosphatidylinositol signaling system
    114210281
   04071 Sphingolipid signaling pathway
    114210281
   04151 PI3K-Akt signaling pathway
    114210281
   04150 mTOR signaling pathway
    114210281
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    114210281
  09143 Cell growth and death
   04115 p53 signaling pathway
    114210281
   04218 Cellular senescence
    114210281
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    114210281
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    114210281
   05206 MicroRNAs in cancer
    114210281
   05208 Chemical carcinogenesis - reactive oxygen species
    114210281
   05230 Central carbon metabolism in cancer
    114210281
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    114210281
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    114210281
   05214 Glioma
    114210281
   05218 Melanoma
    114210281
   05215 Prostate cancer
    114210281
   05213 Endometrial cancer
    114210281
   05224 Breast cancer
    114210281
   05222 Small cell lung cancer
    114210281
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    114210281
   05165 Human papillomavirus infection
    114210281
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    114210281
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    114210281
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    114210281
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:eju01009]
    114210281
Enzymes [BR:eju01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     114210281
    3.1.3.48  protein-tyrosine-phosphatase
     114210281
    3.1.3.67  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
     114210281
Protein phosphatases and associated proteins [BR:eju01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   Phosphatase and Tensin homologs (PTEN)
    114210281
SSDB
Motif
Pfam: Tc-R-P PTP-SAK DSPc PTP-NADK Y_phosphatase PTPlike_phytase Y_phosphatase3 Y_phosphatase2 CDKN3
Other DBs
NCBI-GeneID: 114210281
NCBI-ProteinID: XP_027960337
LinkDB
Position
Unknown
AA seq 198 aa
MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSK
HKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVA
AIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKAVIRGLALLEQNTSTT
IDKISLRMEDRAVHPGAQ
NT seq 597 nt   +upstreamnt  +downstreamnt
atgacagccatcatcaaagagatcgttagcagaaacaaaaggagatatcaagaggatgga
ttcgacttagacttgacctatatttatcccaacattattgctatggggtttcctgcagaa
agacttgaaggcgtatacaggaacaatattgatgatgtagtaaggtttttggattcaaag
cataaaaaccattacaagatatacaatctgtgtgctgaaagacattatgataccgccaaa
tttaactgcagagttgcacagtatccttttgaagaccataatccaccacagctagaactt
atcaaacccttttgtgaagatcttgaccaatggctaagtgaagatgacaatcatgttgca
gcaattcactgtaaagctggaaagggacgaactggtgtaatgatttgtgcatatttatta
catcggggcaaatttttaaaggcacaagaggccctagatttctatggggaagtaaggacc
agagacaaaaaggctgtgattcgaggcttggcactcctggagcagaatacctccacaaca
atagataagatttctctcaggatggaagacagagccgtgcaccccggtgcacagtga

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