Eumetopias jubatus (Steller sea lion): 114211152
Help
Entry
114211152 CDS
T07240
Symbol
PTK2
Name
(RefSeq) focal adhesion kinase 1 isoform X1
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
eju
Eumetopias jubatus (Steller sea lion)
Pathway
eju01522
Endocrine resistance
eju04012
ErbB signaling pathway
eju04062
Chemokine signaling pathway
eju04148
Efferocytosis
eju04151
PI3K-Akt signaling pathway
eju04360
Axon guidance
eju04370
VEGF signaling pathway
eju04510
Focal adhesion
eju04517
IgSF CAM signaling
eju04518
Integrin signaling
eju04670
Leukocyte transendothelial migration
eju04810
Regulation of actin cytoskeleton
eju04935
Growth hormone synthesis, secretion and action
eju05100
Bacterial invasion of epithelial cells
eju05135
Yersinia infection
eju05146
Amoebiasis
eju05163
Human cytomegalovirus infection
eju05165
Human papillomavirus infection
eju05170
Human immunodeficiency virus 1 infection
eju05200
Pathways in cancer
eju05202
Transcriptional misregulation in cancer
eju05205
Proteoglycans in cancer
eju05208
Chemical carcinogenesis - reactive oxygen species
eju05222
Small cell lung cancer
eju05417
Lipid and atherosclerosis
eju05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
eju00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
114211152 (PTK2)
04370 VEGF signaling pathway
114211152 (PTK2)
04151 PI3K-Akt signaling pathway
114211152 (PTK2)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
114211152 (PTK2)
04518 Integrin signaling
114211152 (PTK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
114211152 (PTK2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
114211152 (PTK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
114211152 (PTK2)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
114211152 (PTK2)
04062 Chemokine signaling pathway
114211152 (PTK2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
114211152 (PTK2)
09158 Development and regeneration
04360 Axon guidance
114211152 (PTK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
114211152 (PTK2)
05202 Transcriptional misregulation in cancer
114211152 (PTK2)
05205 Proteoglycans in cancer
114211152 (PTK2)
05208 Chemical carcinogenesis - reactive oxygen species
114211152 (PTK2)
09162 Cancer: specific types
05222 Small cell lung cancer
114211152 (PTK2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
114211152 (PTK2)
05163 Human cytomegalovirus infection
114211152 (PTK2)
05165 Human papillomavirus infection
114211152 (PTK2)
09171 Infectious disease: bacterial
05135 Yersinia infection
114211152 (PTK2)
05100 Bacterial invasion of epithelial cells
114211152 (PTK2)
09174 Infectious disease: parasitic
05146 Amoebiasis
114211152 (PTK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
114211152 (PTK2)
05418 Fluid shear stress and atherosclerosis
114211152 (PTK2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
114211152 (PTK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
eju01001
]
114211152 (PTK2)
01009 Protein phosphatases and associated proteins [BR:
eju01009
]
114211152 (PTK2)
Enzymes [BR:
eju01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
114211152 (PTK2)
Protein kinases [BR:
eju01001
]
Non-receptor tyrosine kinases
FAK family
114211152 (PTK2)
Protein phosphatases and associated proteins [BR:
eju01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
114211152 (PTK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_C_FAK1
FERM_N_2
FERM_M
Kinase-like
Haspin_kinase
FERM_F2
ABC1
Motif
Other DBs
NCBI-GeneID:
114211152
NCBI-ProteinID:
XP_027961431
LinkDB
All DBs
Position
Unknown
AA seq
1099 aa
AA seq
DB search
MLLELAGQGALRPAGAVCMEKSGCSPFPMCWAKEYDRYIASSKIMAAAYLDPNLNHTPNS
STKPHLGTGVERSPGAMERVLKVFHYFENSSEPATWASIIRHGDATDVRGIIQKIVDSHK
VKHVACYGFRLSHLRSEEVHWLHLDMGVSNVREKYELAHPPEEWKYELRIRYLPKGFLNQ
FTEDKPTLNFFYQQVKSDYMSEIADRVDQDIALKLGCLEIRRSYWEMRGNALEKKSNYEV
LEKDVGLKRFFPRSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKE
CFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFNQVQTIQYSNSEDKDRKGML
QLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGATQSFIIRPQKEGERALPSIPKL
ANSEKQGMRTHAVSVSETDDYAEIIDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDV
HQGVYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVW
IIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSS
NDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEIL
MHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQL
STILEEEKVQQEERMRMESRRQVTVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHM
VQTNHYQVSAYPGSHGITAMAGSIYPGQASLLDQTDSWNPRPQEISMWQPNVEDSAALDL
RGIGQVLPTHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPTG
NQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPGDSYNEGVKPWRLQPQEISPPP
TANLDRSNDRVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETLP
VLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKN
LLDVIDQARLRMLGPTRPH
NT seq
3300 nt
NT seq
+upstream
nt +downstream
nt
atgttgctggaactggcgggccaaggggccctgagaccagcaggtgccgtctgtatggag
aagagcggctgtagtccatttccaatgtgttgggctaaagagtatgacagatacatagca
tctagcaaaataatggcagctgcttaccttgacccaaacttgaatcacacaccgaattcg
agtaccaagcctcacctgggtactggagtggaacgttcccctggggcaatggagcgagtg
ttgaaggtctttcattattttgaaaacagcagtgagccagccacttgggccagtattatc
aggcatggagatgctactgatgtcaggggcatcattcagaagatagtggacagtcacaaa
gtaaagcacgtggcctgctatggatttcgcctcagtcacctgcggtcagaggaggttcac
tggctccatttggatatgggtgtctccaatgtgagggagaagtatgaacttgcacaccca
ccagaggagtggaaatatgaattgagaattcgttatttgccaaaaggatttctaaaccag
tttactgaggacaagccaactctgaatttcttctatcaacaggtgaagagcgactacatg
tctgagatagctgaccgcgtggaccaggacattgctttgaagctgggctgtctagagata
cggcgctcgtactgggagatgcgaggcaacgcgctagagaagaagtccaactatgaagtg
ctggaaaaagatgttggtttgaagcgattttttcctaggagtttactggattctgtcaag
gccaaaacactaagaaagctgatccaacagacatttagacagtttgccaatcttaacaga
gaagaaagtattctgaagttctttgagatcctctccccagtgtacagatttgataaagaa
tgcttcaagtgtgctctgggttcaagctggattatttcggtagaactggcaattggccca
gaagaaggaatcagttacctcacggacaaggggtgcaaccccacacatctggccgacttc
aatcaagtgcagaccattcagtattcaaacagcgaagacaaggacaggaaagggatgcta
cagctgaaaattgccggcgccccagagcctctgacagtgacagcaccatccctgaccatc
gctgagaatatggctgacttgatagatgggtactgccggctggtgaacggggccacacag
tcttttatcatcagaccccagaaagaaggtgaacgggctttaccatcaataccaaagctg
gccaacagcgagaagcaaggcatgcggacacacgcggtctccgtatcagaaacagatgat
tatgctgagattatagacgaagaagatacctacaccatgccctcaaccagggattatgag
attcagagagaaagaatcgagcttggacggtgcattggggaaggccagtttggagacgtc
catcaaggcgtctatatgagcccagagaatccagctttggcggttgcaattaaaacatgt
aaaaactgtacttcggacagcgtgagagagaaattccttcaagaagccttaacgatgcgc
cagtttgaccaccctcacattgtgaaactgattggtgtcatcacggagaaccctgtctgg
ataatcatggagctgtgcacgcttggagagctgaggtcatttctgcaagtaaggaagtac
agtttggatctggcgtctttgatcctatatgcctatcagcttagtacagccctcgcgtat
ctggagagcaaaagatttgtgcacagggacattgctgctcggaatgttctggtatcctca
aatgattgtgtaaaactaggagactttggattatcccgatatatggaagacagtacttac
tacaaagcttccaaaggaaaattgccaattaagtggatggctccagagtccatcaatttt
cgacgttttacctcagctagtgatgtatggatgtttggtgtatgtatgtgggagatactg
atgcatggtgtgaagccttttcaaggagtgaagaacaatgatgtgatcggtcgaattgag
aatggggagagattaccaatgcctccaaattgccctcctaccctctacagccttatgacg
aaatgctgggcctatgaccccagcaggcggccccggttcactgagctcaaagctcagctc
agcacaatcctggaagaggagaaggttcagcaagaagaacggatgaggatggagtccaga
agacaggtcacagtgtcctgggactccggagggtccgacgaagcgccacccaagcccagc
agacccggttacccgagtccaaggtccagtgaaggattttatcccagcccacagcacatg
gtacaaaccaatcattaccaggtctctgcctatcctggttcacatgggatcacggccatg
gctggcagcatctacccgggtcaggcatctcttttggaccagacggattcctggaatcct
agaccgcaggagatatcaatgtggcagcccaacgtggaggactctgctgcactggacctg
cgtgggatcggacaggtgttgccgacccacctgatggaagagcggctgatccggcagcag
caggagatggaagaagatcagcgctggctagaaaaagaggagagattcctgaaacctgac
gtgcggctctctcgaggcagtatcgacagggaggatggaagtctccagggtccgactgga
aaccaacacatatatcagcctgtggggaaaccagatcctgcggctccgccaaagaaaccg
ccacggcctggggcccccggtcacctgggcagcctcgccagcctcagcagccccggggac
agttacaacgagggcgtcaagccatggaggcttcagccccaggaaatcagccccccaccc
actgccaacctggaccggtccaacgacagggtgtacgagaatgtgacgggcctggtgaag
gctgtcatcgagatgtccagcaagatccagcctgccccgccagaggagtacgttcccatg
gtgaaggaagtcggcctggccctgcggacgttactggccactgtggacgagaccctccca
gtcctgccagccagcactcaccgagagattgagatggcccagaagctgttgaactccgac
ctgggtgagctcatcaacaagatgaaactggcccagcagtacgtcatgaccagtctccag
caggagtacaaaaagcaaatgctgaccgcggctcacgccctggccgtggacgccaaaaac
ttactcgatgtcattgaccaagcgagactgcggatgctcggaccgacgaggccacactga
DBGET
integrated database retrieval system
