Eumetopias jubatus (Steller sea lion): 114215744
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Entry
114215744 CDS
T07240
Symbol
PDPK1
Name
(RefSeq) 3-phosphoinositide-dependent protein kinase 1
KO
K06276
3-phosphoinositide dependent protein kinase-1 [EC:
2.7.11.1
]
Organism
eju
Eumetopias jubatus (Steller sea lion)
Pathway
eju01524
Platinum drug resistance
eju03320
PPAR signaling pathway
eju04068
FoxO signaling pathway
eju04071
Sphingolipid signaling pathway
eju04140
Autophagy - animal
eju04150
mTOR signaling pathway
eju04151
PI3K-Akt signaling pathway
eju04152
AMPK signaling pathway
eju04210
Apoptosis
eju04360
Axon guidance
eju04510
Focal adhesion
eju04660
T cell receptor signaling pathway
eju04664
Fc epsilon RI signaling pathway
eju04722
Neurotrophin signaling pathway
eju04910
Insulin signaling pathway
eju04919
Thyroid hormone signaling pathway
eju04931
Insulin resistance
eju04960
Aldosterone-regulated sodium reabsorption
eju05145
Toxoplasmosis
eju05205
Proteoglycans in cancer
eju05208
Chemical carcinogenesis - reactive oxygen species
eju05213
Endometrial cancer
eju05215
Prostate cancer
eju05223
Non-small cell lung cancer
eju05231
Choline metabolism in cancer
eju05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
eju00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
114215744 (PDPK1)
04071 Sphingolipid signaling pathway
114215744 (PDPK1)
04151 PI3K-Akt signaling pathway
114215744 (PDPK1)
04152 AMPK signaling pathway
114215744 (PDPK1)
04150 mTOR signaling pathway
114215744 (PDPK1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
114215744 (PDPK1)
09143 Cell growth and death
04210 Apoptosis
114215744 (PDPK1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
114215744 (PDPK1)
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
114215744 (PDPK1)
04664 Fc epsilon RI signaling pathway
114215744 (PDPK1)
09152 Endocrine system
04910 Insulin signaling pathway
114215744 (PDPK1)
03320 PPAR signaling pathway
114215744 (PDPK1)
04919 Thyroid hormone signaling pathway
114215744 (PDPK1)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
114215744 (PDPK1)
09156 Nervous system
04722 Neurotrophin signaling pathway
114215744 (PDPK1)
09158 Development and regeneration
04360 Axon guidance
114215744 (PDPK1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
114215744 (PDPK1)
05208 Chemical carcinogenesis - reactive oxygen species
114215744 (PDPK1)
05231 Choline metabolism in cancer
114215744 (PDPK1)
09162 Cancer: specific types
05215 Prostate cancer
114215744 (PDPK1)
05213 Endometrial cancer
114215744 (PDPK1)
05223 Non-small cell lung cancer
114215744 (PDPK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
114215744 (PDPK1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
114215744 (PDPK1)
09167 Endocrine and metabolic disease
04931 Insulin resistance
114215744 (PDPK1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
114215744 (PDPK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
eju01001
]
114215744 (PDPK1)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
eju04131
]
114215744 (PDPK1)
Enzymes [BR:
eju01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
114215744 (PDPK1)
Protein kinases [BR:
eju01001
]
Serine/threonine kinases: AGC group
PDK1 family
114215744 (PDPK1)
Membrane trafficking [BR:
eju04131
]
Exocytosis
Calcium ion-dependent exocytosis
Acrosomal exocytosis proteins
114215744 (PDPK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PH_3
PK_Tyr_Ser-Thr
Kinase-like
Pkinase_fungal
ABC1
Haspin_kinase
APH
Kdo
Motif
Other DBs
NCBI-GeneID:
114215744
NCBI-ProteinID:
XP_027967746
LinkDB
All DBs
Position
Unknown
AA seq
559 aa
AA seq
DB search
MEWRLNPYLYDTVPIQSSVVLCACPSPSMVRTQTESGIVPGIPTGGSRQGPTMDSTAAES
RPSTNSLQHTTQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRH
IIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSF
DETCTRFYTAEMVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQA
RANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKL
EYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMGGYGPLRAHPFFESITWENLQHQTPPK
LTAYLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSASDAGLPQTAGSNIEQYIH
DLDTNSFELDLEFSEDEKRLLLEKQASGNPWHQFVENNLILKMGPVDKRKGLFARRRQLL
LTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCK
KIQEVWRHRYQSHPDAAVQ
NT seq
1680 nt
NT seq
+upstream
nt +downstream
nt
atggagtggagactgaatccatacttgtatgacactgttccaattcagtccagcgtggtg
ttatgtgcttgcccatccccatcaatggtgaggacccagactgagtccggcatagtccct
ggcattcccaccggtggtagcagacagggccccaccatggacagcactgcggccgagtcc
cgaccgagcaccaactcgctgcagcacaccacacagccaccaccacagcctcggaagaaa
cggcctgaagacttcaagtttgggaaaattcttggtgaaggctctttttctacagttgtc
ctggcccgagaactggcaacctcaagggaatacgctattaaaattctagagaaacgtcac
attatcaaagagaacaaggtcccgtatgtaaccagagagagagacgtgatgtcacgcctg
gatcacccgttctttgttaaactttacttcacatttcaggatgatgaaaagctgtacttt
ggtcttagttatgccaaaaatggagaactccttaaatacattcgcaaaattggctcattc
gatgagacgtgcacccggttttacacggccgagatggtgtcagctctggagtacttgcat
ggcaagggcatcattcacagagacctgaaaccggaaaacattttgttaaatgaagacatg
cacatccagatcacagatttcggaacagcaaaagtactatccccggagagtaaacaagct
agggccaactcgtttgtaggaacagcccagtatgtgtctccagagctgctcacggagaag
tcggcctgtaaaagttcagacctttgggctctcggatgtataatataccagcttgtggca
ggactgccgccttttcgagcgggaaatgaatatcttatatttcagaagatcattaagttg
gaatatgactttcctgaaaaattcttccctaaggcaagagaccttgtggaaaaacttttg
gttttagatgccacgaagcgattaggctgtgaggaaatgggagggtacggacccctgcga
gcgcatccgttcttcgagtccatcacgtgggagaacctgcagcatcagacgcctccgaag
ctcaccgcctacctgccagccatgtcagaggatgacgaggactgctacggaaactacgac
aacctcctgagccagttcggctgcatgcaggtgtcctcgtcctcctcctcccactccctg
tccgcctcggatgcaggcctgccgcagacggcgggcagcaacatcgagcagtatatccat
gacctggacactaattcttttgaactggacttagagttctccgaagatgagaagaggttg
ttactggagaagcaggccagtggaaacccttggcaccagtttgtagaaaataacctaata
ctaaagatgggtcccgtagataagcggaagggtttgtttgcacgacgacgacagttactg
cttacagaagggccacacttgtattacgtggatcctgtcaacaaagtcctgaaaggcgaa
attccatggtcacaagaactccgaccggaggccaagaattttaaaaccttcttcgtgcac
acgccgaacaggacgtattacctgatggacccgagtgggaatgctcacaaatggtgcaaa
aagatccaggaagtgtggagacacagataccagagccacccagatgctgctgtgcagtga
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