Eumetopias jubatus (Steller sea lion): 114220667
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Entry
114220667 CDS
T07240
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
eju
Eumetopias jubatus (Steller sea lion)
Pathway
eju04120
Ubiquitin mediated proteolysis
eju04144
Endocytosis
eju04330
Notch signaling pathway
eju04668
TNF signaling pathway
eju04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
eju00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
114220667 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
114220667 (ITCH)
04668 TNF signaling pathway
114220667 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
114220667 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
114220667 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
eju04131
]
114220667 (ITCH)
04121 Ubiquitin system [BR:
eju04121
]
114220667 (ITCH)
Enzymes [BR:
eju01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
114220667 (ITCH)
Membrane trafficking [BR:
eju04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
114220667 (ITCH)
Ubiquitin system [BR:
eju04121
]
Ubiquitin ligases (E3)
HECT type E3
114220667 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
114220667
NCBI-ProteinID:
XP_027974467
LinkDB
All DBs
Position
Unknown
AA seq
862 aa
AA seq
DB search
MSGSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIFETLKSNNMKLEEVVVTL
QLVGDKEPTETIGDLSVCLDGLQLESEVVTNGETTCSESASQNDDGSRPKDETRTNTNGS
DEPEDAGAGENRKVNGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESE
GSSTGSLPPTNINSNTSEGATSGLIIPLTISGGSGPRPLNSVPQAPLPPGWEQRVDQHGR
VYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFTTSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNT
RITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFNPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
GRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGL
EMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctggcagtggatcacagcttggttcaatgggtagcctgaccatgaaatcacaactt
cagatcactgtcatttcagcaaaacttaaagaaaataaaaagaattggtttggaccaagt
ccttatgtggaagtcacagtagacggacagtcaaagaagacagaaaaatgcaacaatacg
aacagtcccaaatggaagcaaccccttacagttatcgtcacccctgtgagtaaattacat
tttcgtgtgtggagtcaccagacactgaaatctgatgttttgttgggaactgctgcatta
gatatctttgaaaccttaaagtcaaacaacatgaaacttgaggaagtagttgtgacttta
cagcttgtaggtgacaaagaaccaacagagacaataggagacttgtcagtttgtcttgat
gggctgcagttggagtctgaagttgttaccaatggtgaaactacatgttcagaaagtgct
tcacagaatgatgatggctccagacccaaggatgaaacaagaacaaacacaaatggatca
gatgagcctgaggatgcaggggctggtgaaaataggaaggtcaatgggaataattctcca
tcactctcaaatggtggttttaaaccttctaggcctccaagaccttcacgaccacctcca
cctaccccacgtagaccagcatctgtcaatggttcaccatctgccacttctgaaagtgag
ggatccagtacaggctctctgccaccaacaaatataaattcaaatacatctgaaggagca
acatctggattaataattcctctgactatatctggaggctcaggccctaggccattaaat
tctgtacctcaggctcccctaccacctggttgggagcagagagtggaccagcatggacga
gtttactatgtagatcatattgaaaaaagaacaacctgggatagaccagaacctctacct
cctggctgggaacggcgggttgacaacatgggacgtatttactatgttgaccatttcaca
agaacaacaacgtggcagaggccaacgctggaatctgtccggaactatgaacagtggcag
ctccagcgtagtcagctgcaaggagcaatgcagcagtttaaccagagatttatttatggg
aatcaagatttgtttactacatcacaaaataaagaatttgatccccttggtcccctgcca
cctggatgggagaagagaacagacagcaatggtagagtatattttgtcaaccacaacact
cgtattacacaatgggaagaccccagaagtcaaggccaattaaatgaaaagcccttacct
gaaggctgggaaatgagattcacagttgatggaattccatattttgtggaccacaataga
agaacaaccacctatattgatccccgcactggaaaatctgccctagacaatggaccacag
atagcctatgtacgggacttcaaggcaaaagttcagtatttccggttctggtgtcagcaa
ctggccatgccacagcacataaagattacagtgacaagaaagacattgtttgaagattcc
tttcagcagataatgagcttcaatccccaagatctgcgaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagagagtggttctttcttttgtca
cacgaggtgttgaacccaatgtattgcctgtttgaatatgcagggaaagataactactgc
ttgcagattaatcctgcttcttacatcaatccagatcacctgaaatattttcgttttatt
ggcaggtttattgccatggctctgttccatgggaaattcatagacacaggtttttctttg
ccattctataagcgtatattgaacaaaccagttggactcaaggatttagaatctattgat
ccagaattttacaattctctcatctgggttaaagaaaacaatattgaggaatgtggtttg
gaaatgtacttctctgtcgataaagaaattttaggtgaaatcaagagtcatgatttgaaa
cctaatggtggaaatattcttgtgacagaagaaaataaagaggaatatatcagaatggta
gctgaatggaggttgtctcgaggtgttgaagaacagacacaagctttctttgagggcttt
aatgaaattcttccccagcagtatttgcaatactttgatgcaaaggaattagaggtcctt
ttatgtggaatgcaagagattgatttgaatgactggcaaagacatgccatctaccgtcat
tacactaggacaagcaaacaaatcatgtggttttggcagtttgttaaagaaattgataat
gagaagagaatgagacttctgcagtttgttactggaacctgccggttgccagttggagga
tttgctgacctcatggggagcaatggaccacaaaaattctgcattgaaaaagttggaaaa
gaaaattggttgcccagaagtcatacgtgttttaaccgcctggacctgccaccctacaag
agctatgagcaactgaaagaaaagctgttatttgccattgaagaaacagaaggatttgga
caagagtaa
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