Eumetopias jubatus (Steller sea lion): 114223527 Help Entry 114223527         CDS       T07240                                  Symbol CASP8 Name (RefSeq) caspase-8   KO K04398   caspase 8 [EC:3.4.22.61] Organism eju  Eumetopias jubatus (Steller sea lion) Pathway eju01524   Platinum drug resistance eju04115   p53 signaling pathway eju04210   Apoptosis eju04215   Apoptosis - multiple species eju04217   Necroptosis eju04620   Toll-like receptor signaling pathway eju04621   NOD-like receptor signaling pathway eju04622   RIG-I-like receptor signaling pathway eju04623   Cytosolic DNA-sensing pathway eju04625   C-type lectin receptor signaling pathway eju04657   IL-17 signaling pathway eju04668   TNF signaling pathway eju04932   Non-alcoholic fatty liver disease eju04936   Alcoholic liver disease eju05010   Alzheimer disease eju05016   Huntington disease eju05022   Pathways of neurodegeneration - multiple diseases eju05132   Salmonella infection eju05134   Legionellosis eju05142   Chagas disease eju05145   Toxoplasmosis eju05152   Tuberculosis eju05160   Hepatitis C eju05161   Hepatitis B eju05162   Measles eju05163   Human cytomegalovirus infection eju05164   Influenza A eju05165   Human papillomavirus infection eju05167   Kaposi sarcoma-associated herpesvirus infection eju05168   Herpes simplex virus 1 infection eju05169   Epstein-Barr virus infection eju05170   Human immunodeficiency virus 1 infection eju05200   Pathways in cancer eju05203   Viral carcinogenesis eju05416   Viral myocarditis eju05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:eju00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     114223527 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     114223527 (CASP8)    04215 Apoptosis - multiple species     114223527 (CASP8)    04217 Necroptosis     114223527 (CASP8)    04115 p53 signaling pathway     114223527 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     114223527 (CASP8)    04621 NOD-like receptor signaling pathway     114223527 (CASP8)    04622 RIG-I-like receptor signaling pathway     114223527 (CASP8)    04623 Cytosolic DNA-sensing pathway     114223527 (CASP8)    04625 C-type lectin receptor signaling pathway     114223527 (CASP8)    04657 IL-17 signaling pathway     114223527 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     114223527 (CASP8)    05203 Viral carcinogenesis     114223527 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     114223527 (CASP8)    05161 Hepatitis B     114223527 (CASP8)    05160 Hepatitis C     114223527 (CASP8)    05164 Influenza A     114223527 (CASP8)    05162 Measles     114223527 (CASP8)    05168 Herpes simplex virus 1 infection     114223527 (CASP8)    05163 Human cytomegalovirus infection     114223527 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     114223527 (CASP8)    05169 Epstein-Barr virus infection     114223527 (CASP8)    05165 Human papillomavirus infection     114223527 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     114223527 (CASP8)    05134 Legionellosis     114223527 (CASP8)    05152 Tuberculosis     114223527 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     114223527 (CASP8)    05142 Chagas disease     114223527 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     114223527 (CASP8)    05016 Huntington disease     114223527 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     114223527 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     114223527 (CASP8)    05416 Viral myocarditis     114223527 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     114223527 (CASP8)    04932 Non-alcoholic fatty liver disease     114223527 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     114223527 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:eju01002]     114223527 (CASP8) Enzymes [BR:eju01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      114223527 (CASP8) Peptidases and inhibitors [BR:eju01002]  Cysteine peptidases   Family C14: caspase family    114223527 (CASP8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED PYRIN Motif Other DBs NCBI-GeneID:  114223527 NCBI-ProteinID:  XP_027978309 LinkDB All DBs Position Unknown AA seq 486 aa AA seqDB search MNFSKCLYNIGEQLDSDELASLKFLSMDCIPQKKQEPIKDPLMLFQRLQEKRMLEEGNLS FLKELLFRINRLDLLVTYLDTSKEEMEQELQIPGRAQISAYRVMLFQISEDVSKLELRSF KFLLSQEISRCKLHDDLNLLDIFIEMEKRVILGERNLDTLKRICDQINKSLLKKITDYEE LSRELTMSPQRSLDEVSNDMSQLLIGEESLRVPPMSDSPGEQDYESETSEKVYRMESKPR GYCLIFNNYDFSIARKEVPKLQSIKDRNGTDLDADALCQTFSELHFEIVPFRDSTAMKIC EVLKSYQSMDHTSRDCFICCVLSHGDKGIIYGSDGREVPIYELTSYFTGSKCPSLAGKPK IFFIQACQGDNYQKGIAVETDSEQKEAYLEMDSLWQKRYIPEDADFLLGMATVNNCVSYR NPMEGTWYIQSLCQSLRERCPRGEDILTILTEVNFEVSNKDDRKNMGKQMPQPTFTLRKK LFFPPN NT seq 1461 nt NT seq  +upstreamnt  +downstreamnt atgaatttcagcaaatgcctctataatattggagagcagctggacagtgatgagctggcc tccctcaaattccttagcatggactgcatcccacagaaaaagcaggaacccatcaaggat cccttgatgttattccagagactccaggaaaagagaatgttggaggaaggcaacctgtcc ttcttgaaggagctgcttttccgaattaatagactggatctgctggtcacctacctggac accagcaaggaggagatggagcaggaacttcagataccaggcagagcccagatctctgcc tacagggtcatgctttttcagatttcagaagatgtaagcaaattggaattgaggtccttt aagtttcttttgagccaggagatctccagatgtaaactgcatgatgatttgaacttgctt gatattttcatagagatggagaagagggtcatcctcggggaaagaaatttggacaccctg aaaagaatctgtgaccaaattaacaagagcctgctgaagaaaatcacggattatgaagaa ttaagcagagagctaacaatgagccctcaaagaagtctagatgaagtttcaaatgatatg tctcagttgcttataggggaggaatccctgagggtaccgccaatgtcggactctccagga gaacaggactatgaatcagagacatcagagaaagtttaccgaatggaaagcaaacctcga ggatattgtttgatctttaacaattatgactttagcatagcacggaaggaagtgcccaaa cttcagagcattaaggataggaatggaacagacttggatgcagatgctttgtgtcagacc tttagtgagcttcattttgagattgtgcctttccgagactctacagccatgaaaatctgt gaggttctgaaatcctaccaaagcatggaccacactagcagggattgctttatctgctgt gtcctctcccatggagacaagggcatcatctatggctctgatgggcgggaagtccccatc tatgagctgacgtcttacttcactggctcaaagtgcccttcccttgcaggcaagcccaaa attttttttattcaggcttgtcaaggggataactaccagaaaggtatagctgttgagact gactccgaacagaaggaagcctatttagaaatggactcgttgtggcagaagagatatatt ccagaagatgctgactttctgctggggatggccactgtgaacaattgtgtttcctaccga aatcccatggaggggacctggtatatccagtcactttgccagagcctaagagaaagatgt cccaggggtgaagatattctcaccatccttaccgaggtgaactttgaagtgagcaataag gatgacagaaaaaacatggggaagcaaatgccacaacctactttcacactgaggaaaaaa ctcttcttccctcctaattga

DBGET integrated database retrieval system