KEGG   Escherichia coli clone D i2: i02_0050
Entry
i02_0050          CDS       T02004                                 
Symbol
folA
Name
(GenBank) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
eld  Escherichia coli clone D i2
Pathway
eld00670  One carbon pool by folate
eld00790  Folate biosynthesis
eld01100  Metabolic pathways
eld01240  Biosynthesis of cofactors
eld04981  Folate transport and metabolism
Module
eld_M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:eld00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    i02_0050 (folA)
   00670 One carbon pool by folate
    i02_0050 (folA)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    i02_0050 (folA)
Enzymes [BR:eld01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     i02_0050 (folA)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: AER82648
LinkDB
Position
51608..52222
AA seq 204 aa
MRRVQGESVDSPAEYKIFLNIILAPVDDGLRFTYSGDNFFYREISMISLIAALAVDRVIG
MENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWV
KSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWES
VFSEFHDADAQNSHSYCFEILERR
NT seq 615 nt   +upstreamnt  +downstreamnt
atgcggcgagtccagggagagagcgtggactcgccagcagaatataaaattttcctcaac
atcatcctcgcaccagtcgacgacggtttacgctttacgtatagtggcgacaattttttt
tatcgggaaatctcaatgatcagtctgattgcggcgttagcggtagatcgcgttatcggc
atggaaaacgccatgccgtggaacctgcctgccgatctcgcctggtttaaacgcaacact
ttaaataaacccgtgattatgggccgccatacctgggaatccatcggtcgtccgttgcca
ggacgcaaaaatattatcctcagcagtcaaccgggtacggacgatcgcgtaacgtgggtg
aagtcggtggatgaagccattgcggcgtgtggtgacgtaccagaaatcatggtgattggc
ggcggtcgcgtttatgagcagttcctgccgaaagcgcaaaaactgtatctgacgcatatc
gacgcggaagtggaaggcgacacccatttcccggattacgagccggatgactgggaatcg
gtattcagcgaattccacgatgccgatgcgcagaactctcacagctattgctttgagatt
ctggagcggcggtaa

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