Enhydra lutris kenyoni (northern sea otter): 111145007
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Entry
111145007 CDS
T05871
Name
(RefSeq) proto-oncogene tyrosine-protein kinase receptor Ret
KO
K05126
proto-oncogene tyrosine-protein kinase Ret [EC:
2.7.10.1
]
Organism
elk
Enhydra lutris kenyoni (northern sea otter)
Pathway
elk04010
MAPK signaling pathway
elk04020
Calcium signaling pathway
elk04151
PI3K-Akt signaling pathway
elk05200
Pathways in cancer
elk05216
Thyroid cancer
elk05223
Non-small cell lung cancer
elk05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
elk00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
111145007
04020 Calcium signaling pathway
111145007
04151 PI3K-Akt signaling pathway
111145007
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
111145007
05230 Central carbon metabolism in cancer
111145007
09162 Cancer: specific types
05216 Thyroid cancer
111145007
05223 Non-small cell lung cancer
111145007
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
elk01001
]
111145007
Enzymes [BR:
elk01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
111145007
Protein kinases [BR:
elk01001
]
Receptor tyrosine kinases (RTK)
RET family
111145007
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
RET_CLD1
RET_CLD4
RET_CLD3
Pkinase
RET_CRD
Cadherin
RIO1
Pkinase_fungal
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
111145007
NCBI-ProteinID:
XP_022355345
UniProt:
A0A2Y9JC58
LinkDB
All DBs
Position
Unknown
AA seq
1053 aa
AA seq
DB search
MEAPLGLYFSRDAYWEKLYVDQPAGMPLLYVHALRDAPEEVPSFRLGQHLYGIAYRARLQ
ENDWIRIEEDTGLLYLNRSLDHSAWERLSIRNGGFPVLTIYLQVFLASASLREGECQWPG
CARVYFSFINTSFPACSSLKPRELCFPETGVSFRIRENRPPGTFHQFRLLPVQFLCPNIS
VSYRLLEGENLPFHCAPDSLEVSTRWALDRELREKYELVAACTVHIGAHKEQVVMVPFPV
TVYDEDDSAPTFLGGLDTASAVVEFKRKEGTVVATIRVFDADVVPASGELLRRYTSTLLP
GDTWALQTFRIEHSPNETLAQANGSFVRATVHDYRLVLNRSLPISESRSLQLAVLVNDSD
FQGPGEGVLRLHFNVTVLPVSLHLPSAYSFTMSRQARRFAQIGKVCVDNCQEFSGIHVQY
KLQLSSANCSVLGVVTSAEDTTGTLFVNDTEALQRPDCSQLQYTVVAADRPSRRQTQAPL
VVTVEGTYVAEEPGCPLSCAVSKRRPECEECGGLGSLTGRCEWRQGDGKGITRNFSTCSP
SVKTCPDGHCDAVESRNVNICPQDCLRGGSIIGGHEPGERWGIKAGFGICNCFPEEKKCF
CEPEDSQDPLCDELCRTVIAAAVLFSFIVSMLLSTFCIHRYHKNAHKPPIASAEMTFRRP
AQAFPVSYSSSGARRPSLDSMENQVSVDAFKIPEDPKWEFPRKNLVLGKTLGEGEFGKVV
KATAFRLKGKAGYTTVAVKMLKENASPSELRDLLSEFNLLKQVNHPHVIKLYGACSQDGP
LFLIVEYAKYGSLRGFLRESRKAGPGDVGSGGSRSSSYLDSPGERALTMGDLISFAWQIS
RGMRYLAEMKLVHRDLAARNVLVAEGRKMKISDFGLSRDVYEEDSYVKRSKGRIPVKWMA
IESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGYRMERPDNCSEE
MYGLMLQCWKQEPDKRPVFADISKDLEKMMVKNRDYLDLAASTPSDSLLYDDGLSEEETP
LVDCNSAPLPRALPSTWIENKLYGRISHAFTRF
NT seq
3162 nt
NT seq
+upstream
nt +downstream
nt
atggaggctccactaggactctacttctccagggacgcttactgggagaaactgtatgtg
gaccagccagctggcatgcccctgctctatgtccacgccctgcgggacgcccccgaggag
gtgcccagcttccgcctgggccagcacctctacggcatcgcctaccgtgcgaggctgcag
gagaacgactggatccgcatcgaggaggacacgggccttctctaccttaaccggagcctg
gaccacagcgcctgggagaggctcagcatccgcaatggcggcttccccgtgctcaccatc
tacctccaggtcttcctggcatctgcgtccctacgtgagggcgagtgccagtggccaggc
tgtgcccgggtatacttctccttcatcaacacctccttcccggcttgcagttccctcaaa
ccccgggagctctgctttcccgagacaggcgtctccttccgcatcagagagaacaggcct
cctggcaccttccaccaattccggctgctgcctgtgcaattcctctgccccaacatcagc
gtgtcctataggctcctagaaggtgagaatctgcccttccactgcgccccggacagcctg
gaggtgagcacacgctgggccctggaccgtgagctgcgagagaaatacgagctggtggcc
gcgtgcacggtgcacatcggcgcgcacaaggagcaggtggtgatggtgcccttccctgtg
accgtgtacgatgaggacgactcggcgcccaccttcctcgggggcttggacaccgccagc
gctgtggtggagttcaagaggaaggagggcaccgtggtggccacaatacgtgtcttcgac
gcagacgtggtgccggcctctggggagctgctgaggcggtacacaagcacactactgcca
ggggacacctgggccctgcagactttccgcatcgagcactcacccaacgagaccttggcc
caggctaatggcagcttcgtgcgggcaactgtgcatgactacaggctggttctcaaccgg
agcctccccatctcggagagccgctccctgcagctggctgtgctggtcaatgactcggac
ttccagggccccggcgagggcgtcctccgcctccatttcaacgtgaccgttctgcctgtc
agcctgcacttacccagcgcctactccttcactatgagcaggcaggcccgccgctttgcc
cagattgggaaagtctgcgtggacaactgccaggagttcagtggcatccacgtgcagtac
aagctgcagctctccagcgccaactgcagcgtcctgggggtggtcacctccgctgaggac
accacgggaaccctgtttgtgaatgacacggaagccctgcagcggcctgattgctctcaa
ctccagtacacagtggtggccgccgaccggccaagccgcaggcagacccaggccccactg
gtcgtcaccgtggaggggacatatgtggccgaggaaccaggctgccccctgtcctgtgca
gtcagcaagaggcggcctgagtgtgaggagtgtggcggcctgggctctctgacgggcaga
tgtgagtggagacagggagacggcaaaggaatcaccaggaacttctccacctgctccccc
agcgtcaagacctgccccgacggccactgtgatgctgtggagagcagaaacgtcaacatc
tgtccccaggactgcctccggggcggcagcatcattggtgggcacgagccaggggagcgc
tgggggataaaagctggcttcggtatctgcaactgtttccccgaagagaagaagtgcttc
tgtgaacctgaagacagccaggacccactgtgtgatgagctgtgccgcacggtgatcgcg
gcagccgtgctcttctccttcatcgtatccatgctgctctccaccttctgcatccaccgc
taccacaagaatgcccacaagccgcccatcgcctctgccgagatgactttccgccggccg
gcccaggccttcccggtcagctactcctcgtcgggcgcccgccggccctccctggactcc
atggagaaccaggtctctgtggacgcctttaagatcccggaggatccaaagtgggaattc
ccccggaagaacttggttcttggaaaaactctgggagaaggcgaatttggaaaagtggtt
aaagcaacagccttccggcttaaaggcaaagcagggtacacaactgtggctgtgaagatg
ctaaaagagaacgcctccccaagtgagctgcgggacctgctgtcagagttcaacctcctg
aagcaggtcaaccacccgcatgtcatcaagctgtatggggcctgcagccaggatgggccg
ctcttcctcattgtggagtacgccaagtatggctccctgcggggcttcctccgggagagc
cgcaaggctggcccgggcgacgtgggcagcgggggcagccgcagctccagctacctggac
agccccggggagcgggccctgaccatgggcgacctcatctccttcgcctggcagatctct
cgggggatgcggtacctggcggagatgaagcttgtccatcgggacttggcagccagaaac
gttctggtagccgaggggcggaagatgaagatttcagatttcggcctgtcccgagatgtt
tatgaagaggattcctatgtgaagaggagcaagggtcggattccagtcaaatggatggca
attgagtctcttttcgatcacatctacaccacccaaagcgacgtgtggtcctttggtgtc
ctgctatgggagattgtgactctagggggcaacccctaccccgggattcctccagagcgg
ctcttcaaccttctaaagacaggctaccggatggagaggcctgacaactgcagtgaggag
atgtacggcctaatgctacagtgctggaagcaggaaccggacaagaggccggtgtttgct
gacatcagcaaagacctggagaagatgatggttaagaacagagactacttggacttggcc
gcgtccaccccatctgactccctgctttacgacgacggcctctcggaggaggagacgccc
ctggtggactgtaatagcgctcccctccctcgagccctcccctccacgtggattgaaaac
aaactctatggtagaatttcacatgcatttactagattctag
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