Enhydra lutris kenyoni (northern sea otter): 111147115
Help
Entry
111147115 CDS
T05871
Name
(RefSeq) insulin receptor substrate 2
KO
K07187
insulin receptor substrate 2
Organism
elk
Enhydra lutris kenyoni (northern sea otter)
Pathway
elk04022
cGMP-PKG signaling pathway
elk04068
FoxO signaling pathway
elk04081
Hormone signaling
elk04140
Autophagy - animal
elk04152
AMPK signaling pathway
elk04211
Longevity regulating pathway
elk04213
Longevity regulating pathway - multiple species
elk04910
Insulin signaling pathway
elk04920
Adipocytokine signaling pathway
elk04923
Regulation of lipolysis in adipocytes
elk04930
Type II diabetes mellitus
elk04931
Insulin resistance
elk04932
Non-alcoholic fatty liver disease
elk04935
Growth hormone synthesis, secretion and action
elk05010
Alzheimer disease
elk05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
elk00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
111147115
04022 cGMP-PKG signaling pathway
111147115
04152 AMPK signaling pathway
111147115
09133 Signaling molecules and interaction
04081 Hormone signaling
111147115
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
111147115
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
111147115
04923 Regulation of lipolysis in adipocytes
111147115
04920 Adipocytokine signaling pathway
111147115
04935 Growth hormone synthesis, secretion and action
111147115
09149 Aging
04211 Longevity regulating pathway
111147115
04213 Longevity regulating pathway - multiple species
111147115
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
111147115
09164 Neurodegenerative disease
05010 Alzheimer disease
111147115
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
111147115
04932 Non-alcoholic fatty liver disease
111147115
04931 Insulin resistance
111147115
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
IRS
PH
PH_11
MEKK4_N
Motif
Other DBs
NCBI-GeneID:
111147115
NCBI-ProteinID:
XP_022358725
UniProt:
A0A2Y9JLI9
LinkDB
All DBs
Position
Unknown
AA seq
1330 aa
AA seq
DB search
MASPPLHGAPGPAGGDGPNLNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGDEAAAAA
AGGGPAPQPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTKDEY
FAVAAENEQEQEGWYRALTDLVSEGRAGDGPPAAATAASCSASLPGALGGSAGAAAADDS
YGLVAPATAAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTLQLM
NIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEFRPR
SKSQSSGSSSTHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCRVRT
ASEGDGGAAAGAGAAGGRPVSVAGSPLSPGPVRAPLSRSHTLSGGCGARASKAAPAPAGG
ALQHSRSMSMPVARSPPAATSPGSLSSSSGHGSGSYPPPPGAHPHLPHPLHQPAGQRPSS
GSASASGSPSDPGFMSLDEYGSSPGDLRAFCGHRSNTPESIAETPPARDGGGGELYGYMT
MDRPLSHCGRPYRRVSGDGAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMRAT
FSGSSGRLCPTCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGVALLG
GGSGSCKSDDYMPMSPTSVSAPKQILQPRTAVAPALPPTGTAVPAPTPTVSRAFPASGGS
YKTSSPAESSPEDSGYMRMWCGSKLSMENADTKLLPNGDYLNMSPSDAGTSGTPPDFFSA
ALHGSGEMLRGVPGYCYSSLPRSYKAPYTCNGDNDQYVLMSSPVGRILEEERLEPPASPG
AAPSSSAFAAGGGHSQPPHPVVPSPSRPSGSSGGRPEGFPNQRARLVRPTRLSLEGLQTL
PSMHEYPLPSEPKSPGEYINIDFGDAGARLSPPAPPLLASAASSSSLLSASSPASSLGSG
TPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGTQSGDPVGSLDALLSPQASSPYPPLPPRP
AAPASSLQPQHPPPPPPGELYRLPQASTCQGPSAASSSSSETGDNGDYTEMAFGVAATPP
QPIAAPPKPEGARVTSPTSGLKRLSLMDQVSGVEAFLQASQPPDPHRGAKVIRADPQGGR
RRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGGSGVLGGGEEHPMSP
RQLQPPPPQQARPWVPSQPGGLVGCPGGSSSPMCRETSAGFQNGLNYIAIDVRDEPGLSP
TPQQHPHPQPGDKSAWGRTRSLGGLISAVGGSGSSGVCGGPGPGALPSANTYASIDFLSH
HLKEATVVKE
NT seq
3993 nt
NT seq
+upstream
nt +downstream
nt
atggcgagcccgccgctgcacggggcccccgggccggcgggcggcgacggccccaacctc
aacaacaacaacaacaacaaccacagcgtgcgcaagtgcggctacctgcgcaagcagaag
cacggccacaagcgcttcttcgtgctgcgcgggcccggcgacgaggcggcggcggcggcg
gcgggcgggggtccggcgccgcagccgccgcggctcgagtactacgagagcgagaagaag
tggcggagcaaggcgggcgccccgaagcgggtcatcgcgctcgactgctgcctgaacatc
aacaagcgcgccgacgccaagcacaagtacctgatcgcgctctacaccaaggacgagtac
ttcgcggtggcggccgagaacgagcaggagcaggagggctggtaccgcgcgctcaccgac
ctggtcagcgagggccgcgcgggcgacgggcccccggccgccgccaccgccgcgtcctgc
agcgcttccctgcccggcgccctgggcggctcggccggcgccgccgcggcggatgacagc
tacgggctggtggcgccagccacggccgcctaccgcgaggtgtggcaggtgaacctgaag
cccaagggcctgggccagagcaagaacctgacgggcgtgtaccgcctgtgcctgtcggcg
cgcaccatcggcttcgtgaagctcaactgcgagcagccgtcggtgacgctgcagctgatg
aacatccggcgctgcggccactcggacagcttcttcttcatcgaggtgggccgctcggcc
gtcacgggcccgggcgagctgtggatgcaggcggacgactcggtggtggcgcagaacatc
cacgagaccatcctggaggccatgaaggccctcaaggagctgttcgagttccggccgcgc
agcaagagccagtcgtcgggctcgtcctccacacaccccatcagcgtccccggcgcgcgc
cgccaccaccacctggtcaacctgcccccgagccagacgggcctggtgcgccgctcgcgc
acggacagcctggccgccaccccgccggccgccaagtgcagctcgtgtcgggtgcgcacg
gccagcgagggcgacggcggcgcggcggcgggcgcgggggcggcgggcggcaggcccgtg
tcggtggccgggagtcccctgagccccgggccggtgcgcgcgcccctgagccgctcgcac
accctgagtggcggctgcggggcccgcgcgagcaaggcggcgccggcgccggcagggggc
gccctgcaacacagccggtccatgtccatgcccgtggcgcgctcgcccccggccgccacc
agccccggcagcctgtcgtccagcagcgggcacggctccggctcctacccgccgcccccc
ggcgcgcacccgcacctgccgcaccccctgcaccagcccgccggccagcggccctccagc
ggcagcgcctcggcctcgggctcccccagcgaccccggcttcatgtccctggatgagtac
ggctccagccccggcgacctgagagccttctgcggccacaggagcaacacgcccgagtcc
atcgccgagactcccccggcccgggacggcggcgggggcgagctgtatgggtacatgact
atggaccggcccctgagccactgcggccgcccctaccgcagagtgtcgggggacggggcc
caggacctggaccgagggctgaggaagaggacttactccctgaccacgcctgcccggcag
cggccggtgccgcagccctcctccgcgtccctggatgagtacaccctgatgcgggccacc
ttctctggcagctccggccgcctctgcccgacctgtcccgcgtcgtctcccaaagtggcc
taccatccctatcccgaggactacggcgacatcgagatcgggtcccacaggagctccagc
agtaacctgggtgccgacgatggctacatgcccatgacccctggcgtggccctcctgggt
gggggcagtggcagctgtaagagtgatgattacatgcccatgagccccactagcgtgtcc
gccccgaagcagatcctgcagcctcgcactgctgtggccccagccctgccccccacggga
accgcggtgcccgcgcccacccctacagtcagcagggcgtttccagcgagcgggggcagc
tacaagacgagctccccggccgagagctccccggaggacagtgggtacatgcgtatgtgg
tgtggctccaagctgtccatggagaacgctgacaccaagctgctccccaacggggactac
ctcaatatgtcccccagcgatgccggtacctcggggacccctcccgacttcttctctgcc
gccttgcatggcagcggggagatgctcaggggagtccctggctactgctatagctccctg
ccccgctcctacaaggctccctacacctgcaacggggacaacgaccagtacgtgctcatg
agctcccccgtcgggcgcatcctggaagaggagaggctcgaaccgcccgccagcccgggg
gccgcgccttccagcagcgccttcgcggcgggaggcggccacagccagcctcctcaccca
gtagtgccttcgcccagcaggccgagcggcagcagcggcggccgcccagagggcttcccg
aaccagcgcgcccggttagtgcggcccacacgcctgtccctggaggggctgcagaccctg
cccagcatgcacgagtaccctctgccgtccgagcccaagagccccggcgagtacatcaac
attgactttggcgacgccggagctcgcctgtctccgcccgcacctccgctgctggcttcc
gcggcctcctcgtcctcactgctgtccgccagcagcccggcctcgtccctgggctccggc
accccgggcacgagcagcgacagcaggcagcgctccccgctctctgactacatgaacctc
gacttcagctcgcccaagtcgccgaagccgggcacccagagcggggaccccgtgggctcc
ctggatgccctgctgtccccccaggcctcgtccccctacccgccgctgcccccacgcccc
gctgcccccgcctcctcgctgcagccgcagcatcccccaccgccccccccaggggagctg
taccgcctgccccaggcgtccacttgccagggccccagcgctgcctcctcttcgtcctcg
gagaccggggacaacggtgactacaccgagatggcctttggtgtggctgccaccccgcca
caacccatcgcggcccccccgaagccggaaggtgcccgtgttaccagcccaacgtccggc
ttgaagaggctgagtctcatggatcaggtgtcaggagtcgaggccttcctgcaggctagc
cagcccccagaccctcaccggggagccaaggtcatccgcgcagacccacaggggggccgg
cggcgccacagttccgagaccttctcctcgaccaccactgtgacccccgtgtccccgtcc
ttcgcccataaccctaagcgccacaactcggcctccgtggaaaacgtctctctcaggaaa
agcagtgaagggggcggcagcggcgtcctgggtgggggtgaggagcaccccatgtcccct
cgtcagttgcagccgccgcccccccagcaggcacgcccatgggtaccgagtcagccgggt
ggcttggtgggctgccccgggggcagtagctctccgatgtgcagggagacctctgccggc
ttccagaatggcctcaactacatcgccatcgacgtgagggacgagcctgggctgtcacca
accccacagcagcatccgcatccccagcccggagacaagagcgcctggggccggacccgc
agcctcgggggtctcatcagcgctgtggggggcagcggtagcagtggggtttgcggggga
ccgggccctggcgccctcccctctgccaacacctatgccagcattgacttcttgtcccat
cacctgaaggaggccaccgttgtgaaagagtga
DBGET
integrated database retrieval system
