Enhydra lutris kenyoni (northern sea otter): 111160180
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Entry
111160180 CDS
T05871
Name
(RefSeq) receptor tyrosine-protein kinase erbB-3
KO
K05084
receptor tyrosine-protein kinase erbB-3 [EC:
2.7.10.1
]
Organism
elk
Enhydra lutris kenyoni (northern sea otter)
Pathway
elk01521
EGFR tyrosine kinase inhibitor resistance
elk04010
MAPK signaling pathway
elk04012
ErbB signaling pathway
elk04020
Calcium signaling pathway
elk04151
PI3K-Akt signaling pathway
elk05205
Proteoglycans in cancer
elk05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
elk00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
111160180
04012 ErbB signaling pathway
111160180
04020 Calcium signaling pathway
111160180
04151 PI3K-Akt signaling pathway
111160180
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
111160180
05205 Proteoglycans in cancer
111160180
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
111160180
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
elk01001
]
111160180
Enzymes [BR:
elk01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
111160180
Protein kinases [BR:
elk01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
111160180
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Furin-like
Pkinase
Kinase-like
TM_ErbB1
Motif
Other DBs
NCBI-GeneID:
111160180
NCBI-ProteinID:
XP_022378787
UniProt:
A0A2Y9KXJ4
LinkDB
All DBs
Position
Unknown
AA seq
1339 aa
AA seq
DB search
MRANAALQVLGFLLNLAQGSEVGNSQAVCPGTLNGLSVTGDAENQYQTLYKLYERCEVVM
GNLEIVLTGHNADLSFLQWIREVTGYVLVAMNEFSTLPLPNLRVVRGTQVYDGKFAIFVM
LNYNTNSSHALRQLRFTQLTEILSGGVYIEKNDKLCHMDTIDWRDIVRDRGAEIVVKDNG
RNCPPCHEACKGRCWGPRPEDCQTLTKTICAPQCNGHCFGPNPNQCCHDECAGGCSGPQD
TDCFACRLFNDSGACVRQCPQPLVYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVVDQTS
CVRACPPDKMEVDKNGLKICEPCGGLCPKACEGTGSGSRFQTVDSSNIDGFVNCTKILGN
LDFLITGLNGDPWHKIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGG
RSLYNRGFSLLIMKNLNITSLGLRSLKEISAGRVYISANRQLCYHHSLNWTRLLRGPPEE
RLDIKHNRPRRDCVAEGKVCDPLCSSGGCWGPGPGQCLSCRNYSRGGVCVTHCNFLNGEP
REFAHEAECFSCHLECRPMEGTATCNGSGSDACAQCAHFRDGPHCVSSCPSGVLGAKGPI
YKYPDAQNECRPCHENCTQGCKGPELQDCLGQTLALISKTHLAVGLTVVVGLAVIFLILG
GTFLYWRGRRIQNKRAMRRYLERGESIEPLDPSEKANKVLARIFKETELRKLKVLGSGVF
GTVHKGVWIPEGESIKIPVCIKVIEDKSGRQSFQDVTDHMLAIGSLDHAHIVRLLGLCPG
SSLQLVTQYLPLGSLLDHVRQHRGALGPQLLLNWGVQIAKGMYYLEEHGMVHRNLAARNV
LLKSPSQVQVADFGVADLLPPDDKQLLHSEAKTPIKWMALESIHFGKYTHQSDVWSYGVT
VWELMTFGAEPYAGLRLAEVPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKE
LANEFTRMARDPPRYLVIKRESGPGIPPGAEPPALTNKELEEVELEPELELDLDLEAEED
GLAATLGSALSLPVGTLNRPRGSQSLLSPSSGYMPMNQGNLGETGQESAFCGSGEQCPRP
ASLHPMPRGRLASESSEGHVTGSEAELQEKVSMCRSRSRSPRPRGDSAYHSQRHSLLTPV
TPLSPLGLEEEDVNGYVMPDAHLKGTPSSREGTLSSVGLSSVLGTEEEDEDDEYEYMNRR
RRRSPTRPPRPSSLEELGYEYMDVGSDLSASLGSTQSCPLNPVPLMPAAGTTPDEDYEYM
NRRHGGGAPGGDYAAMGACPAAEQGYEEMRAFQGPGHHAPHVHCARLKTLRSLEATDSAF
DNPDYWHSRLFPKANAQRT
NT seq
4020 nt
NT seq
+upstream
nt +downstream
nt
atgagggcgaacgcggctctgcaggtgctgggctttcttctcaacctggcccagggctcc
gaggtgggcaactcccaggcagtgtgtcctgggactctgaatgggctgagtgtgacgggc
gatgccgagaaccagtaccagacgttgtacaagctctacgagaggtgtgaggtggtgatg
gggaaccttgagattgtgctcacgggacacaatgctgacctctccttcctgcagtggatc
cgagaagtgaccggctatgtcctcgtggccatgaacgagttctctacgctgccactgccc
aacctccgggtggtgcgcgggactcaggtgtacgatgggaagtttgccatctttgtcatg
ttgaactataacaccaactccagccacgccctgcgccagctccgcttcactcagctcact
gagattctgtcagggggcgtttatattgagaagaacgataaactttgtcacatggacaca
atcgactggagggacatcgtgagggaccgaggtgcagagatagtggtgaaggacaatggc
aggaactgtcccccatgtcatgaggcctgcaaggggcgatgctggggtcctagaccagag
gattgccagacattgaccaagaccatctgtgcccctcaatgtaatggtcactgctttggg
cccaaccccaaccagtgctgccatgatgagtgcgcaggcggctgctcaggccctcaggac
acagactgctttgcctgtcgactcttcaatgacagtggggcctgtgtgcgccagtgtcca
cagcctctagtctacaacaagctaactttccagctggaacccaacccccacaccaagtat
cagtacggaggagtttgtgtggccagctgtccccataactttgtagtggatcaaacatct
tgtgttcgggcctgtcctcctgacaaaatggaagtagataaaaatggactcaaaatatgt
gaaccttgtggggggctctgccccaaagcctgcgaagggacaggctctgggagccgcttc
cagactgtggactctagcaacattgatggatttgtgaactgcaccaagatcctgggcaac
ctggactttcttatcactggcctcaatggagacccctggcacaagatccctgccctggac
cctgagaagctcaatgtcttccggacagtacgggagatcacaggttacctgaacatccag
tcctggcctccccacatgcacaacttcagtgtcttttccaacctgacaaccatcgggggc
agaagcctatacaaccggggtttctctttgttaatcatgaagaacttgaatataacatct
ttgggcctccgatctttgaaagaaattagtgccgggcgtgtctacataagtgcgaacagg
cagctctgctaccaccattctctgaactggaccaggcttcttcgggggcctcctgaagag
agactagacatcaagcataatcggcctcgcagagactgtgtggccgagggcaaagtgtgt
gatcccctgtgctcctctggaggatgctggggcccaggtcctggtcagtgcctctcctgt
cgaaactacagccgaggaggtgtctgtgtgacccactgcaactttctgaatggggagcct
cgtgagtttgcccatgaggctgaatgcttctcctgccacctggagtgccgacccatggag
ggtactgccacatgcaatggctcgggctctgatgcttgtgctcagtgtgcccattttcga
gatgggccccactgtgtgagcagctgccccagtggcgtccttggggccaagggtccgatc
tacaagtatccagatgctcagaatgaatgtcggccctgccacgagaattgcacccagggg
tgcaagggaccagagctacaagactgtttaggtcaaacactggcactgatcagcaaaacc
catctggcagtgggtttaacagtggtagtaggattggcagtgattttcctgatccttgga
ggcactttcctctactggcgtgggcgtcggattcagaataagagggctatgaggcgctac
ttggaacggggtgagagcatagagcctctggatcccagtgagaaggctaacaaagtcttg
gccagaatcttcaaagaaacagagctgaggaagcttaaagtgcttggctcaggcgtcttt
ggaaccgtgcacaaaggagtatggatacctgagggggaatcaatcaagattccagtctgc
attaaagtcattgaggacaagagtggacgacaaagttttcaagatgtgacggatcatatg
ctggccattggcagcctagaccatgcccacattgtacggctgctgggactgtgcccaggg
tcatctctgcagctcgtcactcagtacttgcctctgggttccctgctggatcacgtgaga
caacaccgtggagcgctggggccccagctgctgctcaattggggagtacagattgccaag
gggatgtactaccttgaggagcatggtatggtgcacaggaacctggcggcccgaaatgtg
ctactgaagtcacccagtcaggttcaggtggcagattttggggtggctgacttgctgccc
cctgatgataagcaactactacacagtgaggccaagactccaattaagtggatggccctg
gagagtatccactttgggaaatacacacaccagagtgacgtctggagttatggagtgaca
gtttgggagctgatgacctttggggcagaaccctatgctgggctacgactggctgaagta
ccagacctgctagagaagggggagcgactggcgcagccccagatctgtaccatcgatgtc
tacatggtcatggtcaagtgttggatgattgatgagaacattcgtccaacctttaaagaa
ctagccaatgagttcaccaggatggcccgagacccaccacggtatctggtcataaagaga
gagagtgggcctggaattccccctggggcagagccccctgctctgacaaacaaggaactg
gaggaggtggagctggagccagaactggagctagacctggatttggaggcagaggaggat
ggtctggcggccacactaggctctgccctcagcctgccggtgggaacacttaatcggccc
cgtgggagccagagtcttttaagcccatcatctggatacatgcctatgaaccagggtaat
cttggggagactggccaggagtctgcattttgtgggagtggtgagcagtgcccccgtcca
gcctctttgcacccaatgccacggggacgcctggcatcagagtcctcagagggccatgtg
acaggctctgaggctgagctccaggagaaggtgtcaatgtgtaggagccggagccggagc
ccccggccacgtggagacagtgcctaccattcccagcgccatagcctgctcactcctgtc
accccactctccccactagggttagaggaagaggatgtcaatggatatgtcatgccagat
gcacacctcaaaggtactccctcctcccgggaaggtaccctttcttcagtgggcctcagt
tctgtcctgggtaccgaagaagaagatgaagatgatgagtatgagtacatgaaccggagg
agaaggcgcagtccaactcgtccccctaggcccagttctctcgaggagctgggttatgag
tacatggatgtgggatcagacctcagtgcttccctgggcagcacacagagttgcccactc
aaccctgtgcccctcatgcctgctgctggcacaaccccagatgaggactatgaatatatg
aatcggcgacatggtggaggagctcccgggggagattacgcagccatgggggcctgccca
gcggctgagcaagggtatgaagagatgagagctttccaggggcctggacaccatgccccc
catgtccactgtgctcgcctcaaaactctccgtagtttagaagccactgactccgctttt
gataaccctgattactggcatagcaggcttttccccaaggctaatgctcagagaacataa
DBGET
integrated database retrieval system
