Enhydra lutris kenyoni (northern sea otter): 111161266
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Entry
111161266 CDS
T05871
Name
(RefSeq) insulin receptor substrate 4
KO
K17446
insulin receptor substrate 4
Organism
elk
Enhydra lutris kenyoni (northern sea otter)
Pathway
elk04022
cGMP-PKG signaling pathway
elk04068
FoxO signaling pathway
elk04081
Hormone signaling
elk04140
Autophagy - animal
elk04152
AMPK signaling pathway
elk04211
Longevity regulating pathway
elk04213
Longevity regulating pathway - multiple species
elk04910
Insulin signaling pathway
elk04920
Adipocytokine signaling pathway
elk04923
Regulation of lipolysis in adipocytes
elk04930
Type II diabetes mellitus
elk04935
Growth hormone synthesis, secretion and action
elk05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
elk00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
111161266
04022 cGMP-PKG signaling pathway
111161266
04152 AMPK signaling pathway
111161266
09133 Signaling molecules and interaction
04081 Hormone signaling
111161266
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
111161266
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
111161266
04923 Regulation of lipolysis in adipocytes
111161266
04920 Adipocytokine signaling pathway
111161266
04935 Growth hormone synthesis, secretion and action
111161266
09149 Aging
04211 Longevity regulating pathway
111161266
04213 Longevity regulating pathway - multiple species
111161266
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
111161266
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
111161266
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Motif
Pfam:
IRS
PH_11
PH
PH_8
Motif
Other DBs
NCBI-GeneID:
111161266
NCBI-ProteinID:
XP_022380552
UniProt:
A0A2Y9L2T3
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All DBs
Position
Unknown
AA seq
1310 aa
AA seq
DB search
MASGSFSRDQATRRLRAAAAATAAALSAVATTPFLSSGTPTALIGTGSSCPGAMWPSTAT
SSRSDSESDEEDLPVGDEVCKRGYLRKQKHGHRRYFVLKLETADAPARLEYYENARKFRH
SVRAAAAAAAAASGAAVPALIPPRRVITLYQCFSVSQRANAKYRHLIALFTQDEYFAMVA
ENESEQESWYLLLSRLILESKRRRCGTPGALPDGEPAGPAAAAAVAEPPFYKDVWQVIVK
PRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRCGHSEQYFFLEVGRST
VIGPGELWMQVDDCVVAQNMHELFLEKMRALCADEYRARCRSYSISIGAHLLTLLSARRH
LDTLPREPGGWLRRSRFEQFYHLRAIGDGEDEMPLTRRYLTPSEPVPTSRRARLHLPRAR
RSRRAISAPAGYFRRLPTSPVRVPHPAEVPNHRAGLSPEASGSGNSGEEDSPQGQETQEG
NGGDYMPMNRWGSGNGRGSGSGQGSSGQGSSSQGSRGSQCSGGGQGSSGGQGSSGGQGAG
GNQRSGDGQGTAGGQGSGSGQGASGGGHGSGGGRAPGDGHGSGGGKSHGGGKGSGSGKTS
EGNGERGKSLKKRSYFGKLTQSKQHVPPPPPPPPPAGATGGKGKSGGRFRLYFCADRGTP
KERKEAKEVKDLETLEGVAQGPHRARAFDEDEDDPYVPMRPGVAAPLPSSSDYMPMAPQN
FAPSKMHHSRSPFEDSRGYMMMFPRVSSPPAPSPPKEADPEKEDESKDNDSESDYMFMAP
GAGAIPKNPPNPQGGSSSKNWSSYVSLPNPFQGSALGQSDHSEYVPMLPGKFPGKGLDKE
ASSSGGPKDAVSKPSAEGSFSKRGDGASLTKPSDDGPPKNKAKRPNSLSFITRGNKIKPK
SQKPTREQRGADSSHDYVNIDFTKRESNVPAPFIHGLPGSWGIIAGPRPSAFSNYVNVEL
GLPFPNPAHRLSNLLRAIPGANPLYLEGARWPLVPLPPNTAGGSVNEEEGDYIEVIFNPA
MTPALPFGDRAIRYDAETGRIYVVDPFSECCMDISLSPGRCSEPPPVARLLQEEQQPERR
RPQSRSQSFSGSARAAVSAFSTDSLERDLSSPLAAAAAASAAAPALALSQAFAAASALVV
APGIGAAARGLEAAAGFNSASARWFQPVAGAAAAAEAVRGAPNVAGGSNLRAPNPSADLA
GGENGAAAAAPRPPPRRPVPRPPGREDPYDDDDDDDDDIYVRMDFARPDNKKFDSPRRGP
GTEAAVKNFPMVKESDFIATKTHFRRQVMLMKFHLCPLQICLKERKFRGF
NT seq
3933 nt
NT seq
+upstream
nt +downstream
nt
atggcgagtggctccttctctcgcgaccaagcgacaaggagactgagggctgcagcagcg
gcaacggcggcggctctctctgcggtggcgaccaccccgtttctttcctcgggcacccct
accgcactcattgggaccgggtcgtcttgtccgggagccatgtggccctccacggccacc
agctcccggtcagactcggagtccgatgaggaggacctccccgtcggggacgaggtctgc
aaacgcggctaccttcggaagcagaagcacggccacaggcgctacttcgtgctcaaactc
gagacagccgacgccccggctcggctggaatactatgaaaacgccaggaagttccggcac
agtgtccgcgccgcggccgcggcggcggcggctgcctctggcgccgcggtccccgcgctc
atcccgccacggcgtgtgatcaccctgtatcaatgcttctccgtgagccagcgagccaac
gccaaataccgacacctcatcgccctcttcacccaggacgagtacttcgccatggtggcc
gagaacgagtcggagcaggagagctggtacttgctgctcagccgcctcatcctcgagagt
aagcgccgccgctgcggcacgccgggcgcgctgccggatggggagccagccgggccggcg
gctgcagcggcggtggccgagccacccttctacaaggatgtgtggcaggtaatagtcaaa
cccagggggctggggcacagaaaagagctgagcggcgtgttccggctctgtcttaccgat
gaagaggtggtgttcgtgaggctgaacaccgaagtggccagcgtggtcgtccagctcttg
agcatccgtcgctgcgggcactcggagcagtatttcttcttggaagtcggcaggtccacg
gtcatcggccccggggagctctggatgcaggtcgatgactgtgtggtggcccaaaacatg
cacgagctgtttctggagaagatgagagccctgtgcgcagatgagtaccgagcccgctgc
cgcagctacagcatcagcatcggcgcccacctgttaaccctgctgtccgctaggaggcac
ctggacacgctgccgcgcgagcccggcggctggctgagaaggtcccgctttgagcagttt
taccacctcagggccatcggcgacggggaagacgagatgcccctcaccaggcgctacctg
acacccagcgaacccgtgcccacctccaggcgagcaaggctgcacctgcctagagcgcgc
aggtccaggagagcgatttcagcgcctgccggctattttcgccgcctcccaaccagcccg
gtacgtgtcccacatcctgcagaagtcccgaaccacagagctggcctgtctcctgaagcc
tctggatctggcaactctggggaagaagacagcccccaaggccaagagactcaggaagga
aacggaggtgactacatgcccatgaacagatggggctcaggcaacggccggggttccgga
agtggccagggctcaagtggccaaggctccagtagccagggttcacgaggaagccagtgc
tccggcggggggcagggctccagtggtggccagggctccagtggtggccagggtgcagga
ggaaaccagcggtcaggagatggccagggcactgcaggtgggcaaggctcgggcagtggc
cagggagccagcggcggtggacatggctccggtggtggacgggcacccggagatggccat
ggctcaggcgggggtaaaagccatggagggggcaaaggctcaggaagtgggaaaacctcg
gagggcaatggtgaacgtggaaaatctctgaagaaaaggtcctactttggcaaattaact
caaagcaagcagcacgtgccaccccctccacctccacccccaccggctggagcaactggt
ggcaaagggaagtctgggggaaggttccgactttacttttgcgctgacaggggaacccca
aaagaacgcaaagaggccaaggaggtcaaagacttagagacactggaaggtgtagctcag
gggccccacagagccagagcttttgacgaagatgaggatgacccttacgtgccaatgagg
ccgggggtggctgcccctctcccaagctccagtgattatatgccaatggctcctcaaaac
ttcgctccttcaaaaatgcaccactctcgatcaccttttgaagattcaagagggtacatg
atgatgtttcccagagtgagctcaccacctgccccaagtcccccgaaagaggcagatcct
gaaaaggaggatgaatcaaaggacaatgacagtgagagtgactatatgtttatggctcct
ggagccggtgcaattccaaaaaaccccccaaatcctcagggtggctcttcctctaaaaac
tggagctcttacgtttccctgccaaacccttttcagggctccgcattgggacagagtgac
cacagtgagtatgtaccaatgttacccggaaagttcccagggaagggcctagacaaggaa
gcctcatccagcgggggccccaaagatgcagtttcaaagccttcagctgaggggtcattc
tcaaagcgtggagatggggcgtcactgacaaagccttcagatgatggcccccccaagaac
aaggctaagagacctaacagcctctctttcatcacaagaggaaataaaatcaagccaaaa
tcacaaaaacccactcgtgagcagagaggagctgacagctctcacgactacgtcaacatt
gacttcactaagagagagagcaatgtgcctgccccctttattcacggactgccgggttcg
tggggcatcattgctggccccagaccctcagccttttctaactatgtgaacgttgagttg
ggactgccatttccaaacccagcacacaggctctcgaatcttttaagagccattccaggt
gccaaccccctttatctggaaggtgctaggtggccacttgtgcctcttcctcccaacacg
gcaggtggcagtgtgaatgaggaagagggtgactacattgaagtgattttcaatccagca
atgacaccggccttgccttttggtgacagggccattcgctatgatgccgaaacaggtcgc
atctatgtggtcgacccattttcagagtgctgtatggacatttcgctctcccctggccgc
tgttccgagccaccacctgtagccaggctgctgcaggaagaacaacagccagagcgaaga
cgcccgcaaagccgttcgcaaagtttctctgggtcggccagggccgcggtctcggctttc
tcaaccgacagcctcgagagagacctctcgagtcccttggctgcggccgctgctgcttcg
gcagctgctcccgccttagccttgagccaggcgtttgccgccgcctctgccctcgtagtg
gccccgggcatcggggcagccgccaggggcttggaggccgccgcaggctttaactccgcc
tccgcccgctggttccaacctgttgctggcgccgcggccgctgccgaagcggtcagggga
gccccaaacgtggccggtggctcgaacctgagagcccccaacccatctgcagacctagct
ggcggtgagaacggggccgcagcggccgccccccgaccgccgccgcgccgcccggtgccg
agacccccggggcgagaggatccttacgacgacgacgacgacgacgacgacgacatctac
gtgagaatggactttgccagacctgacaacaagaagttcgactctccccgcagaggtcct
ggaactgaagctgctgttaagaactttcccatggtcaaagagagtgatttcattgccaca
aaaacacactttagaagacaagtgatgcttatgaagtttcatctttgtccactccagatc
tgcctaaaagaaagaaaattcagaggcttctga
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