Escherichia coli W: WFL_13820
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Entry
WFL_13820 CDS
T02101
Symbol
tyrA
Name
(GenBank) bifunctional chorismate mutase/prephenate dehydrogenase
KO
K14187
chorismate mutase / prephenate dehydrogenase [EC:
5.4.99.5
1.3.1.12
]
Organism
ell
Escherichia coli W
Pathway
ell00400
Phenylalanine, tyrosine and tryptophan biosynthesis
ell00401
Novobiocin biosynthesis
ell01100
Metabolic pathways
ell01110
Biosynthesis of secondary metabolites
ell01230
Biosynthesis of amino acids
Module
ell_M00024
Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine
ell_M00025
Tyrosine biosynthesis, chorismate => HPP => tyrosine
Brite
KEGG Orthology (KO) [BR:
ell00001
]
09100 Metabolism
09105 Amino acid metabolism
00400 Phenylalanine, tyrosine and tryptophan biosynthesis
WFL_13820 (tyrA)
09110 Biosynthesis of other secondary metabolites
00401 Novobiocin biosynthesis
WFL_13820 (tyrA)
Enzymes [BR:
ell01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.12 prephenate dehydrogenase
WFL_13820 (tyrA)
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.5 chorismate mutase
WFL_13820 (tyrA)
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Motif
Pfam:
CM_2
PDH_C
PDH_N
F420_oxidored
Motif
Other DBs
NCBI-ProteinID:
AFH12421
UniProt:
E0J713
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Position
complement(2906457..2907578)
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AA seq
373 aa
AA seq
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MVAELTALRDQIDEVDKALLNLLAKRLELVAEVGEVKSRFGLPIYVPEREASMLASRRAE
AEALGVPPDLIEDVLRRVMRESYSSENDKGFKTLCPSLRPVVIVGGGGQMGRLFEKMLTL
SGYQVRILEQHDWDRAADIVADAGMVIVSVPIHVTEQVIGKLPPLPKDCILVDLASVKNG
PLQAMLAAHDGPVLGLHPMFGPDSGSLAKQVVVWCDGRKPEAYQWFLEQIQVWGARLHRI
SAVEHDQNMAFIQALRHFATFAYGLHLAEENVQLEQLLALSSPIYRLELAMVGRLFAQDP
QLYADIIMSSERNLALIKRYYKRFGEAIELLEQGDKQAFIDSFRKVEHWFGDYAQRFQSE
SRVLLRQANDNRQ
NT seq
1122 nt
NT seq
+upstream
nt +downstream
nt
atggttgctgaattgaccgcattacgcgatcaaattgatgaagtcgataaagcgctgctg
aatttattagctaagcgtctggaactggttgctgaagtgggcgaggtgaaaagccgcttt
ggactgcctatttatgttccggagcgcgaggcatctatgttggcctcgcgtcgtgcagag
gcggaagctctgggtgtaccgccagatctgattgaggatgttttgcgtcgggtgatgcgt
gaatcttactccagtgaaaacgacaaaggatttaaaacactttgtccgtcactgcgtccg
gtggttatcgtcggcggtggcggtcagatgggacgcctgttcgagaagatgctgaccctc
tcgggttatcaggtgcggattctggagcaacatgactgggatcgagcggctgatattgtt
gccgatgccggaatggtgattgttagtgtgccaatccacgttactgagcaagttatcggc
aaattaccgcctttaccgaaagattgtattctggttgatctggcatcagtgaaaaatgga
ccattacaggccatgctggcggcgcacgatggcccggtactggggttacacccgatgttc
ggcccggacagcggtagcctggcaaagcaagttgtggtctggtgtgatggacgtaagccg
gaagcataccaatggtttctggagcaaattcaggtctggggcgctcggctgcatcgtatt
agcgctgtcgagcacgatcagaatatggcgtttattcaggctctgcgccactttgctact
tttgcttatgggctgcatctggcagaagaaaatgttcagcttgagcaacttctggcgctc
tcttcgccgatttaccgccttgagctggcgatggtcgggcgactgtttgctcaggatccg
cagctttatgccgacattattatgtcgtcagagcgtaatctggcgttaatcaaacgttac
tataagcgtttcggcgaggcgattgagttgctggagcagggcgataagcaggcgtttatt
gacagtttccgcaaggtggagcactggttcggcgattacgcacagcgttttcagagtgaa
agccgcgtgttattgcgtcaggcgaatgacaaccgccagtaa
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