KEGG   Escherichia coli O83 H1 NRG 857C (AIEC): NRG857_00250
Entry
NRG857_00250      CDS       T02068                                 
Symbol
folA
Name
(GenBank) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
eln  Escherichia coli O83:H1 NRG 857C (AIEC)
Pathway
eln00670  One carbon pool by folate
eln00790  Folate biosynthesis
eln01100  Metabolic pathways
eln01240  Biosynthesis of cofactors
eln04981  Folate transport and metabolism
Module
eln_M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:eln00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    NRG857_00250 (folA)
   00670 One carbon pool by folate
    NRG857_00250 (folA)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    NRG857_00250 (folA)
Enzymes [BR:eln01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     NRG857_00250 (folA)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: ADR25481
UniProt: A0A0H3EEX3
LinkDB
Position
51657..52247
AA seq 196 aa
MDSPAEYKIFLNIILAPVDDGLRFTYSGDNFFYREISMISLIAALAVDRVIGMENAMPWN
LPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIA
ACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDA
DAQNSHSYCFEILERR
NT seq 591 nt   +upstreamnt  +downstreamnt
gtggactcgccagcagaatataaaattttcctcaacatcatcctcgcaccagtcgacgac
ggtttacgctttacgtatagtggcgacaattttttttatcgggaaatctcaatgatcagt
ctgattgcggcgttagcggtagatcgcgttatcggcatggaaaacgccatgccgtggaac
ctgcctgccgatctcgcctggtttaaacgcaacactttaaataaacccgtgattatgggc
cgccatacctgggaatccatcggtcgtccgttgccaggacgcaaaaatattatcctcagc
agtcaaccgggtacggacgatcgcgtaacgtgggtgaagtcggtggatgaagccattgcg
gcgtgtggtgacgtaccagaaatcatggtgattggcggcggtcgcgtttatgagcagttc
ctgccgaaagcgcaaaaactgtatctgacgcatatcgacgcggaagtggaaggcgacacc
catttcccggattacgagccggatgactgggaatcggtattcagcgaattccacgacgct
gatgcgcagaactctcatagctattgctttgagattctggagcggcggtaa

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