KEGG   Escherichia coli O44 H18 042 (EAEC): EC042_0050
Entry
EC042_0050        CDS       T02067                                 
Symbol
folA
Name
(GenBank) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
elo  Escherichia coli O44:H18 042 (EAEC)
Pathway
elo00670  One carbon pool by folate
elo00790  Folate biosynthesis
elo01100  Metabolic pathways
elo01240  Biosynthesis of cofactors
Module
elo_M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:elo00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    EC042_0050 (folA)
   00670 One carbon pool by folate
    EC042_0050 (folA)
Enzymes [BR:elo01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     EC042_0050 (folA)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: CBG32884
UniProt: D3H430
LinkDB
Position
56370..56849
AA seq 159 aa
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNI
ILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLAKAQKLYLTHIDAEVE
GDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
NT seq 480 nt   +upstreamnt  +downstreamnt
atgatcagtctgattgcggcgttagcggtagatcgcgttatcggcatggaaaacgccatg
ccgtggaacctgcctgccgatctcgcctggtttaaacgcaacaccttaaataaacccgtg
attatgggccgccatacctgggaatccatcggtcgtccgttgccaggacgcaaaaatatt
atcctcagcagtcaaccgggtacggacgatcgcgtaacgtgggtgaagtcggtggatgaa
gccatcgcggcgtgtggtgacgtaccagaaatcatggtgattggcggcggtcgcgtttat
gagcagttcctggcaaaagcgcaaaaactgtatctgacgcatatcgacgcagaagtggaa
ggcgacacccatttcccggattacgagccggatgactgggaatcggtattcagcgaattc
cacgacgctgatgcgcagaactctcacagctattgctttgagattctggagcggcggtaa

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