KEGG   Escherichia coli O55 H7 RM12579 (EPEC): ECO55CA74_00240
Entry
ECO55CA74_00240   CDS       T02066                                 
Symbol
folA
Name
(GenBank) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
elr  Escherichia coli O55:H7 RM12579 (EPEC)
Pathway
elr00670  One carbon pool by folate
elr00790  Folate biosynthesis
elr01100  Metabolic pathways
elr01240  Biosynthesis of cofactors
elr04981  Folate transport and metabolism
Module
elr_M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:elr00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    ECO55CA74_00240 (folA)
   00670 One carbon pool by folate
    ECO55CA74_00240 (folA)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    ECO55CA74_00240 (folA)
Enzymes [BR:elr01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     ECO55CA74_00240 (folA)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: AEZ38682
LinkDB
Position
54214..54693
AA seq 159 aa
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNI
ILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVE
GDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
NT seq 480 nt   +upstreamnt  +downstreamnt
atgatcagtctgattgcggcgttagcggtagatcgcgttatcggcatggaaaacgccatg
ccgtggaacctgcctgccgatctcgcctggtttaaacgcaacaccttaaataaacccgta
attatgggccgccatacctgggaatccatcggtcgtccgttgccaggacgcaaaaatatt
atcctcagcagtcaaccgggtacggacgatcgcgtaacgtgggtgaagtcggtggatgaa
gccatcgcggcgtgtggtgacgtaccagaaatcatggtgattggcggcggtcgcgtttat
gagcagttcctgccgaaagcgcaaaaactgtacctgacgcatatcgacgcagaagtggaa
ggcgacacccattttccggattacgagccggatgactgggaatcggtattcagcgaattc
cacgacgctgatgcgcagaactctcacagctattgttttgagattctggagcggcggtaa

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