KEGG   Escherichia coli W: ECW_m0534
Entry
ECW_m0534         CDS       T02002                                 
Symbol
acrB
Name
(GenBank) multidrug efflux system protein
  KO
K18138  multidrug efflux pump
Organism
elw  Escherichia coli W
Pathway
elw01501  beta-Lactam resistance
elw01503  Cationic antimicrobial peptide (CAMP) resistance
Brite
KEGG Orthology (KO) [BR:elw00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    ECW_m0534 (acrB)
   01503 Cationic antimicrobial peptide (CAMP) resistance
    ECW_m0534 (acrB)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:elw02000]
    ECW_m0534 (acrB)
   01504 Antimicrobial resistance genes [BR:elw01504]
    ECW_m0534 (acrB)
Transporters [BR:elw02000]
 Other transporters
  Electrochemical potential-driven transporters [TC:2]
   ECW_m0534 (acrB)
Antimicrobial resistance genes [BR:elw01504]
 Gene sets
  Multipdrug resistance modules
   Multidrug resistance, efflux pump MexAB-OprM [MD:M00718]
    ECW_m0534 (acrB)
SSDB
Motif
Pfam: ACR_tran SecD_SecF_C
Other DBs
NCBI-ProteinID: ADT74068
UniProt: E0J0X7
LinkDB
Position
complement(559500..562649)
AA seq 1049 aa
MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDT
VTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQ
EVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGS
QYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL
TSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANAL
DTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQ
NFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVM
AEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL
SVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGR
YLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLT
KEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKD
AMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNG
LEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYR
MLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEA
MELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFS
VMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGL
IEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIF
FVPVFFVVVRRRFSRKNEDIEHSHTVDHH
NT seq 3150 nt   +upstreamnt  +downstreamnt
atgcctaatttctttatcgatcgcccgatttttgcgtgggtgatcgccattatcatcatg
ttggcaggggggctggcgatcctcaaactgccggtggcgcaatatcctacgattgcaccg
ccggcagtaacgatctccgcctcctaccccggcgctgatgcgaaaacagtgcaggacacg
gtgacacaggttatcgaacagaatatgaacggtatcgataacctgatgtacatgtcctct
aacagtgactccacgggtaccgtgcagatcaccctgacctttgagtctggtactgatgcg
gatatcgcgcaggttcaggtgcagaacaaactgcagctggcgatgccgttgctgccgcaa
gaagttcagcagcaaggggtgagcgttgagaaatcatccagcagcttcctgatggttgtc
ggcgttatcaacaccgatggcaccatgacgcaggaggatatctctgactacgtagcggcg
aatatgaaagatgccatcagccgtacgtcgggcgtgggtgatgttcagttgttcggttca
cagtacgcgatgcgtatctggatgaacccgaatgagctgaacaaattccagctaacgccg
gttgatgtcattaccgccatcaaagcgcagaacgcccaggttgcggcgggtcagctcggt
ggtacgccgccggtgaaaggccaacagcttaacgcctctattattgctcagacgcgtctg
acctctactgaagagttcggcaaaatcctgctgaaagtgaatcaagatggttcccgcgta
ctgctgcgtgatgtggcgaagattgagctgggtggtgagaactacgacatcatcgcagag
tttaacggccaaccggcttccggtctggggatcaagctggcgaccggtgcaaacgcgctg
gataccgctgcggcaatccgtgctgaactggcgaagatggaaccgttcttcccgtcgggt
ctgaaaattgtttacccgtacgacaccacgccgttcgtgaaaatctctattcacgaagtg
gttaaaacgctggtcgaagcgatcatcctcgtgttcctggttatgtatctgttcctgcag
aacttccgcgcgacgttgattccgaccattgccgtaccggtggtattgctcgggaccttt
gccgtccttgccgcctttggcttctcgataaacacgctaacaatgttcgggatggtgctc
gctatcggcttgttggtggatgacgctatcgttgtggtagaaaacgtggagcgtgttatg
gcggaagaaggtttgccgccaaaagaagctacccgtaagtcgatggggcagattcagggc
gctctggtcggtatcgcgatggtactgtcggcggtattcgtaccgatggccttctttggc
ggttctactggtgctatctatcgtcagttctctattaccattgtttcagcaatggcgctg
tcggtactggtagcgttgatcctgactccggctctttgtgccaccatgctgaaaccgatt
gccaaaggcgatcacggggaaggtaaaaaaggcttcttcggctggtttaaccgcatgttc
gagaagagcacgcaccactacaccgacagcgtaggcggtattctgcgcagtacggggcgt
tacctggtgctgtatctgatcatcgtggtcggcatggcctatctgttcgtgcgtctgcca
agctccttcttgccagatgaggaccagggcgtatttatgaccatggttcagctgccagca
ggtgcaacgcaggaacgtacgcagaaagtgctcaatgaggtaacgcattactatctgacc
aaagaaaagaacaacgttgagtcggtgttcgccgttaacggcttcggctttgcgggacgt
ggtcagaataccggtattgcgttcgtttccttgaaggactgggccgatcgtccgggcgaa
gaaaacaaagttgaagcgattaccatgcgtgcaacacgcgctttctcgcaaatcaaagat
gcgatggttttcgcctttaacctgcccgcaatcgtggaactgggtactgcaaccggcttt
gactttgagctgattgaccaggctggccttggtcacgaaaaactgactcaggcgcgtaac
cagctgcttgcagaagcagcgaagcaccctgatatgctgaccagcgtacgtccaaacggt
ctggaagataccccgcagtttaagattgatatcgaccaggaaaaagcgcaggcgctgggt
gtttctatcaacgacattaacaccactctgggcgctgcatggggcggtagctatgtgaac
gactttatcgaccgcggtcgtgtgaagaaagtttacgtcatgtcagaagcgaaataccgt
atgctgccggatgatatcggcgactggtatgttcgtgctgctgatggtcagatggtgccg
ttctcggcattctcctcttctcgttgggagtacggttcgccgcgtctggaacgttacaat
ggcctgccatccatggaaatcttaggccaggcggcaccgggtaaaagtaccggtgaagca
atggagctaatggaacaactggcgagcaaactgcctaccggtgttggctatgactggacg
gggatgtcctatcaggaacgcctctccggcaaccaggcaccttcactgtacgcgatttcg
ttgattgtcgtattcctgtgtctggcggcgctgtacgagagctggtcgattccgttctcc
gttatgctggtcgttccgctgggggttatcggtgcgttgctggctgccaccttccgtggc
ctgaccaatgacgtttacttccaggtaggcctgctcacaaccattgggttgtcggcgaag
aacgcgatacttatcgtcgaattcgccaaagacttgatggataaagaaggtaaaggtctg
attgaagcgacgcttgatgcagtgcggatgcgtttacgtccgatcctgatgacctcgctg
gcgtttatcctcggcgttatgccgctggttatcagtactggtgctggttccggcgcgcag
aacgcagtaggtaccggtgtaatgggcgggatggtgaccgcaacggtactggcaatcttc
ttcgttccggtattctttgttgtggttcgccgccgctttagccgcaagaatgaagatatc
gagcacagccatactgtcgatcatcattga

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