Escherichia coli W: ECW_m2446
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Entry
ECW_m2446 CDS
T02002
Symbol
arnA
Name
(GenBank) fused UDP-L-Ara4N formyltransferase/UDP-GlcA C-4'-decarboxylase
KO
K10011
UDP-4-amino-4-deoxy-L-arabinose formyltransferase / UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating) [EC:
2.1.2.13
1.1.1.305
]
Organism
elw
Escherichia coli W
Pathway
elw00541
Biosynthesis of various nucleotide sugars
elw01100
Metabolic pathways
elw01250
Biosynthesis of nucleotide sugars
elw01503
Cationic antimicrobial peptide (CAMP) resistance
Module
elw_M00761
Undecaprenylphosphate alpha-L-Ara4N biosynthesis, UDP-GlcA => undecaprenyl phosphate alpha-L-Ara4N
Brite
KEGG Orthology (KO) [BR:
elw00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00541 Biosynthesis of various nucleotide sugars
ECW_m2446 (arnA)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01503 Cationic antimicrobial peptide (CAMP) resistance
ECW_m2446 (arnA)
Enzymes [BR:
elw01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.305 UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating)
ECW_m2446 (arnA)
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.13 UDP-4-amino-4-deoxy-L-arabinose formyltransferase
ECW_m2446 (arnA)
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GFIT
Motif
Pfam:
Epimerase
GDP_Man_Dehyd
Formyl_trans_N
Formyl_trans_C
3Beta_HSD
NAD_binding_4
NAD_binding_10
Sacchrp_dh_NADP
RmlD_sub_bind
Motif
Other DBs
NCBI-ProteinID:
ADT75877
UniProt:
E0IY58
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All DBs
Position
2524109..2526091
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AA seq
660 aa
AA seq
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MKTVVFAYHDMGCLGIEALLAAGYEISAIFTHTDNPGEKAFYGSVARLAAERGIPVYAPD
NVNHPLWVERIAHLAPEVIFSFYYRHLICDAILQLAPAGAFNLHGSLLPKYRGRAPLNWV
LVNGETETGVTLHRMVKRADAGAIVAQLRIAIAPDDIAITLHHKLCHAARQLLEQTLPTI
KHGNILEIAQRENEATCFGRRTPDDSFLEWHKPASVLHNMVRAVADPWPGAFSYVGNQKF
TVWSSRVHPHASKAQPGSVISIAPLLIACGDGALEIVTGQAGDGITMQGSQLAQTLGLVQ
GSRLNSQPACTARRRTRVLILGVNGFIGNHLTERLLREDHYEVYGLDIGSDAISRFLNHP
HFHFVEGDISIHSEWIEYHVKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLRIIRYC
VKYHKRIIFPSTSEVYGMCSDKYFDEDHSNLIVGPVNKPRWIYSVSKQLLDRVIWAYGEK
EGLQFTLFRPFNWMGPRLDNLNAARIGSSRAITQLILNLVEGSPIKLIDGGKQKRCFTDI
RDGIEALYRIIENAGNRCDGEIINIGNPENEASIEELGEMLLASFEKHPLRHHFPPFAGF
RVVESSSYYGKGYQDVEHRKPSIRNAHRCLDWEPKIDMQETIDETLDFFLRTVDLTDKPS
NT seq
1983 nt
NT seq
+upstream
nt +downstream
nt
atgaaaaccgtcgtttttgcctaccacgatatgggatgcctcggtattgaagccctgctg
gctgccggttacgaaattagcgctatttttactcatactgataatcccggtgaaaaagcc
ttttatggttcggtagctcgtctggcggcggaaagaggcattccggtttatgcgccggat
aacgttaatcatccgctgtgggtggaacgcattgcccacctagcaccagaggtgattttc
tctttttattatcgccatcttatttgcgacgcgattttgcagctcgctcccgcgggtgca
tttaatctgcacggttcgctgttaccaaaatatcgtggtcgcgcgccgctgaactgggtg
ctggtgaacggtgaaacggaaactggcgttacattgcaccgaatggtgaaacgtgccgat
gccggggccattgtggcgcaactgcgcattgccattgcgccagacgatatcgccattacg
ctgcatcataaattgtgccatgccgcgcgccagttgctggaacagacattacccaccatt
aaacacggtaatattctggaaattgcccagcgcgaaaacgaagccacctgttttggtcgc
agaacgccagatgacagtttcctcgaatggcataaaccggcatccgtgctgcacaacatg
gtgcgtgccgtagccgatccgtggccaggtgccttcagctatgttggtaatcagaaattt
accgtctggtcgtcgcgtgttcatcctcatgccagcaaagcacagccggggagcgtgatt
tctattgcaccgctgttgattgcctgtggcgatggcgcgctggaaatcgtcaccggacag
gcgggcgacggcattactatgcagggctcgcaattagcgcagacgctgggcctggtgcaa
ggttcacgcttgaatagccagcctgcctgcaccgcccgacgccgtacccgggtactcatc
ctcggggtaaatggctttattggcaaccatctgacagaacgcctgctgcgcgaagatcat
tatgaagtttacggtctggatattggcagcgatgcgataagccgttttctgaatcatccg
cattttcactttgttgaaggcgatatcagtattcattccgaatggattgagtatcatgtc
aaaaaatgtgatgtcgtcttgccgctggtggcgatagccacgccgattgaatatacccgc
aacccgctgcgcgtatttgaactcgattttgaagagaatctgcgcattatccgctactgc
gtgaagtaccataagcgaatcatcttcccgtcaacttcagaagtttatgggatgtgtagc
gataaatacttcgatgaggaccattctaatttaatcgtcggcccggtgaataaaccacgc
tggatttattcggtatcaaaacaattacttgatcgggtgatctgggcctatggcgaaaaa
gagggtttacagttcaccctcttccgcccgtttaactggatgggaccgcgactggataac
cttaatgcggcacgaatcggcagctcccgcgctattacgcaactcattctcaatctggta
gaaggttcaccgattaagctgattgatggcggaaaacaaaaacgctgctttactgatatt
cgcgatggtatcgaggcgttataccgcattatcgaaaatgcgggaaatcgctgcgacggt
gaaattatcaacattggcaatcctgagaacgaagcgagcattgaggaactgggcgagatg
ctgctggcgagcttcgaaaaacatccgctgcgccatcatttcccaccgtttgcgggcttt
cgcgttgtcgaaagtagcagctactacggcaaaggatatcaggacgtagagcatcgtaaa
ccgagcatccgcaatgcccaccgctgcctggactgggagccgaaaattgatatgcaggaa
accatcgacgaaacgctggatttcttcctgcgcaccgttgatcttacggataaaccatca
tga
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