KEGG   Epinephelus lanceolatus (giant grouper): 117254181
Entry
117254181         CDS       T07331                                 
Symbol
map2k2a
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 2a
  KO
K04369  mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
Organism
ely  Epinephelus lanceolatus (giant grouper)
Pathway
ely04010  MAPK signaling pathway
ely04012  ErbB signaling pathway
ely04068  FoxO signaling pathway
ely04140  Autophagy - animal
ely04148  Efferocytosis
ely04150  mTOR signaling pathway
ely04210  Apoptosis
ely04218  Cellular senescence
ely04270  Vascular smooth muscle contraction
ely04370  VEGF signaling pathway
ely04371  Apelin signaling pathway
ely04540  Gap junction
ely04620  Toll-like receptor signaling pathway
ely04810  Regulation of actin cytoskeleton
ely04910  Insulin signaling pathway
ely04912  GnRH signaling pathway
ely04916  Melanogenesis
ely05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:ely00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    117254181 (map2k2a)
   04012 ErbB signaling pathway
    117254181 (map2k2a)
   04370 VEGF signaling pathway
    117254181 (map2k2a)
   04371 Apelin signaling pathway
    117254181 (map2k2a)
   04068 FoxO signaling pathway
    117254181 (map2k2a)
   04150 mTOR signaling pathway
    117254181 (map2k2a)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    117254181 (map2k2a)
   04148 Efferocytosis
    117254181 (map2k2a)
  09143 Cell growth and death
   04210 Apoptosis
    117254181 (map2k2a)
   04218 Cellular senescence
    117254181 (map2k2a)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    117254181 (map2k2a)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    117254181 (map2k2a)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    117254181 (map2k2a)
  09152 Endocrine system
   04910 Insulin signaling pathway
    117254181 (map2k2a)
   04912 GnRH signaling pathway
    117254181 (map2k2a)
   04916 Melanogenesis
    117254181 (map2k2a)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    117254181 (map2k2a)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    117254181 (map2k2a)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ely01001]
    117254181 (map2k2a)
Enzymes [BR:ely01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     117254181 (map2k2a)
Protein kinases [BR:ely01001]
 Serine/threonine kinases: STE group
  STE7 family
   117254181 (map2k2a)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Pkinase_fungal Kinase-like Haspin_kinase Seadorna_VP7 APH Kdo
Other DBs
NCBI-GeneID: 117254181
NCBI-ProteinID: XP_033478147
LinkDB
Position
5:32920747..32935206
AA seq 399 aa
MPAKRRPVPLNIMPIGEGQATSNTIDAASEANLEALQKKLGELDLDEQQRKRLEAFLTQK
AQVGELKDEDFDPICELGAGNGGVVNKVRHKPSGLVMARKLIHLEIKPAIRNQIIRELQV
LHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEARRIPEEILGKVSIAVLRGL
AYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQG
THYSVQSDVWSMGLSLVELAIGRYPIPPPDAKELEAIFGRAIIDGAEGEPHSNMQRPRPP
GRPGSGHGMDSRPAMAIFELLDYIVNEPPPKLPHGVFTNDFQDFVTKCLIKNPAERADLK
KLMSHTFIKRSEVEEVDFAGWLCKTMGLNQPSTPTRGTE
NT seq 1200 nt   +upstreamnt  +downstreamnt
atgcctgctaaaagaagacccgttcccctgaacattatgcccatcggggagggacaggcc
acctcaaacaccattgatgctgcatctgaagccaaccttgaggccttacaaaagaaactg
ggtgagctggacctggacgagcaacagaggaaacgactggaggcctttctcacccagaaa
gctcaagttggggagctgaaggatgaagattttgaccccatatgtgagctgggcgctggc
aacggaggagtggtcaacaaggtccgccacaaaccctcgggtctggtcatggctcgcaag
cttatccacctggaaatcaagcctgccatcagaaaccagattatcagagagctgcaggtg
ctgcatgaatgcaactccccctacattgtgggcttctatggggccttttacagcgatgga
gagatcagcatctgtatggagcacatggatggtggatccttggatcaggtcctgaaggaa
gccagaagaatcccagaagaaatcctggggaaagttagcatagctgtattgaggggatta
gcctacctgcgtgagaagcaccagatcatgcacagagatgtcaagccctccaacatcctg
gtcaactctcgcggggagatcaagctgtgcgactttggtgtgagcggccagctcatagat
tccatggccaactcctttgttggaacgcgttcctacatgtcgccggagagactgcagggc
actcactactcggttcagtctgacgtatggagcatgggtctgtcactggtggagctggcg
attggccgctaccccatccccccaccagacgccaaagagctggaggccatcttcggacgg
gccatcatcgacggggccgagggagagcctcacagcaacatgcagaggcccagaccaccg
ggcaggcctgggagcggacatgggatggacagtagacctgctatggccatattcgaactt
ttggattacatcgtgaatgagccgccccctaaactgccgcatggagtcttcaccaatgac
ttccaggactttgtgacaaaatgtttgatcaaaaacccagctgagagggcagatctgaag
aagctgatgagtcacacgttcatcaaacgatcagaggtggaggaggtggactttgccggc
tggttgtgcaaaaccatggggctcaaccagcccagtactccgacccgcggcactgagtga

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