Eublepharis macularius (Leopard gecko): 129330101
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Entry
129330101 CDS
T09084
Symbol
PLCG1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1
KO
K01116
phosphatidylinositol phospholipase C, gamma-1 [EC:
3.1.4.11
]
Organism
emc
Eublepharis macularius (Leopard gecko)
Pathway
emc00562
Inositol phosphate metabolism
emc01100
Metabolic pathways
emc04012
ErbB signaling pathway
emc04020
Calcium signaling pathway
emc04070
Phosphatidylinositol signaling system
emc04370
VEGF signaling pathway
Module
emc_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
emc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
129330101 (PLCG1)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
129330101 (PLCG1)
04370 VEGF signaling pathway
129330101 (PLCG1)
04020 Calcium signaling pathway
129330101 (PLCG1)
04070 Phosphatidylinositol signaling system
129330101 (PLCG1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
emc04131
]
129330101 (PLCG1)
Enzymes [BR:
emc01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
129330101 (PLCG1)
Membrane trafficking [BR:
emc04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
129330101 (PLCG1)
Endocytosis
Macropinocytosis
Phospholipase C
129330101 (PLCG1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
SH2
PI-PLC-Y
EF-hand_PLCG2
PH
SH3_1
C2
SH3_9
EF-hand_PLCG1
SH3_2
PH_12
GDPD
EF-hand_6
EF-hand_7
Motif
Other DBs
NCBI-GeneID:
129330101
NCBI-ProteinID:
XP_054835979
UniProt:
A0AA97JEK7
LinkDB
All DBs
Position
5:142142416..142261007
Genome browser
AA seq
1283 aa
AA seq
DB search
MASVFTNGPCLQSEAEGIHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQIIWSRG
SDKIEGAIDIREIQEIRLGRNSRDFDRYQEDPSFRPDQSHCFVILYGMEFRLKTLSLQAT
SEDEVNMWIKGLNWLVADTLKAATPLQIERWLRKQFNSVDRNREDRISAKDLKNMLSQVN
YRVPSMRFLRERLTDMEQRNGDITYGQFAQLYQSLMYNAQKGMSVPFLESSGDRSEHCRV
SLMEFQTFLLECQMELWATDLLLVQEFMFNFLKDPLREIEEPYFSLDEFLTFMFSKENSI
WNSELDIAHPEDMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCW
DGPDGMPVIYHGHTLTTKIKFSDVLATIKEHAFVTSDYPVILSIEDHCSIAQQRNMAQNF
KKVFGDMLLTKPVDISADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSAMYSENDISNS
IKNGILYLEDPINHDWNPHYFVLTSSKIYYSGETTNDLGNEDEEEQKETSNSTELHSTEK
WFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCR
IHSRQDAGSPKFFLTDNLVFNSLYDLITHYQQVPLRCNEFEMRLTEPVPQTNAHESKEWY
HANLTRALAERMLMRVPRDGAFLVRKRSEPNSYAISFRAEGKIKHCRVQQESQTVVLGNS
EFDSLVDLISYYEKHPLYRKMKLRYPINEETLEKIGTAEPDYGALYEGRNPGFYVEANPM
PTFKCAVKALFDYKAQREDELTFTKNAVIQNVEKQEGGWWRGDYGGKKQLWFPSNYVEEV
MSPTGLEPEIEQQLDENSPLGDLLGGVLDVPSCQIAIRPEGKNNRLFVFSISMASISRRS
LDVAADTHEDMLDWVKKIREAAQTADARLSEGKMMERRKKIALELSELVIYCRPVPFDED
KIGTDRACYRDMSSFPETKAEKYVNKIKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPM
WICGSQLVALNFQTPDKPMQMNQALFMCGGRCGFMLQPANMRDDVFDPFDKSTLRGMDPL
SISIEVLGARHLPKNGRGIVCPFVEVEVSGAEYDSAKQKTEMVVDNGLNPAWPSKSFQFH
IHNPEFAFLRFVVYEEDMFSDQNFLAQATFLVKGLKTGYRAVPLKNNYSEGLELASLLVK
IEIFPGKQENGEISPFGASAFRERSGDSPNQLGAGRGREGSFEARYQQPFEDFRMSQEQL
ADHFDNRDRRVLRRTRVNGDNRL
NT seq
3852 nt
NT seq
+upstream
nt +downstream
nt
atggcgtccgttttcaccaacggaccctgcctccagagcgaagccgaaggcatccatctc
tgcaggagcctcgaagtgggcacggtgatgactttgttttactccaagaaatcccagagg
ccagagaggaagacgttccaggtgaagctggagaccaggcagatcatctggagcagaggc
tcggacaagatcgagggagccattgatattcgtgaaatccaagagattcgtctgggaaga
aactcccgagattttgaccgatatcaggaggatccttcttttcgaccggaccagtctcac
tgctttgtcatcctttatggcatggaattcaggctgaaaacactcagcctgcaagccact
tccgaagatgaagtcaacatgtggatcaaagggttgaattggcttgtggcggatacctta
aaggctgctaccccactgcagattgaaagatggctccgaaagcagttcaactcggttgat
cgcaacagagaggacaggatttctgcgaaggatttgaaaaacatgctttctcaagtcaat
taccgagtccctagcatgaggtttctacgggaaaggttaacagacatggagcaaaggaat
ggagatatcacatacggacaatttgcccagttgtaccagagcttgatgtacaatgcacaa
aaagggatgtctgtaccattcttagaaagcagcggtgacagatctgagcactgccgagta
tctctgatggaattccagacatttttactagaatgccagatggaactttgggctactgac
ctcctcttggttcaggagttcatgttcaatttcttgaaggatccattgcgggaaattgaa
gagccttatttttccctagatgagtttctcaccttcatgttctccaaagagaatagcatc
tggaactcggaactcgatattgctcatccagaagacatgaacaatcccctctcccactac
tggatttcctcctcgcataatacgtacttgacaggagatcagttctccagtgaatcctca
ttggaagcttatgctcgttgcctgcgcatgggatgccgctgcattgaactcgattgctgg
gatgggccagatgggatgccggtgatctatcacgggcacacactgaccacaaagatcaag
ttttccgatgtcttggccaccatcaaggagcatgcttttgtgacctctgactatcctgtc
atcctgtccattgaagatcactgtagcattgcccagcagaggaacatggcccagaacttt
aagaaggtgtttggggacatgctgttgaccaagccagtagatatctctgccgatgggctg
ccctctccgaaccagctgaagagaaagatcctcataaagcacaagaaactagctgaaggc
agcgcttacgaagaagtgccaacatctgccatgtattcagagaatgatatcagtaattcg
ataaagaatggaattctctacttggaagatccaatcaatcatgattggaacccccattac
tttgtcctgacaagcagcaaaatatattattccggggagacaaccaacgatctgggaaat
gaggatgaggaagagcaaaaggagacaagcaacagcaccgaacttcactccaccgaaaag
tggttccatggcaagctgggagccgggcgagatggacgccacattgcggagaggctgctg
acagagtactgcatagagacgggagcccccgatggctcttttcttgtgcgtgagagtgag
acctttgttggcgattataccctttcgttctggcgaaatggaaaagtacagcactgccga
atccattcccggcaggatgctggcagccccaagttcttcctcactgataacctggtgttc
aacagtctctatgacctcatcacccactaccagcaggtgccgctcaggtgcaatgaattt
gagatgaggctgacagaacccgtgccacagaccaatgcgcacgagagcaaggaatggtac
cacgctaatctcacccgggctttggcagagcgcatgctgatgagggtgccgcgagacgga
gctttcctggtacgcaagagaagcgagcccaactcctatgccatctccttccgggcggaa
gggaaaatcaagcactgccgagtgcagcaggagagccaaacggttgtcttgggtaattca
gaatttgacagcctggtggatttaatcagttactatgagaagcatccgctgtaccgcaag
atgaagctgaggtatccaataaatgaggagacattggagaagattgggacagcggagcca
gattatggtgctctgtatgaaggacggaatccaggattctatgtggaagccaaccccatg
ccaaccttcaagtgtgctgtcaaagccttgtttgactacaaggcacagcgggaggatgaa
ctgactttcacaaaaaatgccgtcatccagaatgtggaaaaacaagaaggaggctggtgg
agaggagattacgggggtaagaagcagctatggtttccatctaactatgtggaagaagta
atgagtccaactggtctggagccagagatagagcaacaactagatgagaacagtcccctg
ggagacctgcttggaggtgtcctggatgtaccatcctgtcagatcgctatccgccctgaa
gggaagaacaaccgcctgtttgtcttctctatcagcatggcttccatttcgcgaaggtcc
ctggacgtggccgctgatacacatgaagacatgttagactgggtgaagaagatccgggag
gcagcacagactgctgatgccagactctcagaagggaagatgatggagaggaggaagaag
atagcactggagctttctgagctcgtcatctactgtcgccccgtcccctttgatgaagac
aagatcggcacagacagggcctgctacagagacatgtcctccttccctgaaacgaaggca
gagaagtatgtcaacaaaatcaaaggcaaaaagttcctccagtacaaccggctacaactt
tcccgcatctaccccaagggacaacgtcttgactcctccaactatgaccccctgcctatg
tggatctgtggcagtcagttggtggcactcaacttccaaacaccagacaagccgatgcag
atgaatcaggccctgttcatgtgtggaggtcggtgtggtttcatgttgcagccagccaac
atgcgggatgacgtatttgatccctttgacaagagcacccttcgtgggatggaccccctt
tccatctccattgaggtgcttggggctcgacatcttcccaaaaatggaaggggaattgtt
tgcccctttgtagaggttgaggtgtctggagcagaatatgacagtgcaaaacagaagacg
gagatggtggttgacaatggcttaaatcctgcttggccctcgaaatcctttcagttccat
atccataaccctgagtttgccttcctccgttttgtggtgtatgaagaagacatgttcagt
gaccagaacttcttagctcaagccacattcctggttaaaggcctaaagacaggataccga
gctgtgcctttgaagaacaactacagcgagggcctggaactggcctccttgttggtgaaa
attgagatcttccctggcaagcaggagaatggagaaattagcccctttggggcttcagcc
ttccgagagaggtcaggagactctccaaatcagcttggggcaggccgaggcagagaaggc
tccttcgaagcccgctatcaacaaccgtttgaggacttccggatgtcacaggagcaatta
gcagaccattttgacaaccgagatagaagggtacttcgaaggaccagggtgaatggggat
aaccgcctctag
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