Eublepharis macularius (Leopard gecko): 129333879
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Entry
129333879 CDS
T09084
Symbol
PTK2
Name
(RefSeq) focal adhesion kinase 1 isoform X1
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
emc
Eublepharis macularius (Leopard gecko)
Pathway
emc04012
ErbB signaling pathway
emc04148
Efferocytosis
emc04370
VEGF signaling pathway
emc04510
Focal adhesion
emc04810
Regulation of actin cytoskeleton
emc05100
Bacterial invasion of epithelial cells
Brite
KEGG Orthology (KO) [BR:
emc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
129333879 (PTK2)
04370 VEGF signaling pathway
129333879 (PTK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
129333879 (PTK2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
129333879 (PTK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
129333879 (PTK2)
09160 Human Diseases
09171 Infectious disease: bacterial
05100 Bacterial invasion of epithelial cells
129333879 (PTK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
emc01001
]
129333879 (PTK2)
01009 Protein phosphatases and associated proteins [BR:
emc01009
]
129333879 (PTK2)
Enzymes [BR:
emc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
129333879 (PTK2)
Protein kinases [BR:
emc01001
]
Non-receptor tyrosine kinases
FAK family
129333879 (PTK2)
Protein phosphatases and associated proteins [BR:
emc01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
129333879 (PTK2)
BRITE hierarchy
SSDB
Ortholog
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Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_C_FAK1
FERM_N_2
FERM_M
Kinase-like
FERM_F2
Haspin_kinase
ABC1
GIT1_C
Motif
Other DBs
NCBI-GeneID:
129333879
NCBI-ProteinID:
XP_054841787
UniProt:
A0AA97L6U0
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All DBs
Position
7:complement(136309386..136602354)
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AA seq
1070 aa
AA seq
DB search
MAAAYLDPNLNHTPSSSTKTHLSTGMERSPGAMERVLKVFHYFENNSEPATWASIIRHGD
ATDVWGIIQKIVDSHKVKNVACYGLRLSHLQSEEVHWLHPDMGVSNVREKFELSHAPEEW
KYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKNDYMVEIADQVDQEIALKLGCLEIRRSY
WEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESI
LKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGSNPTHLADFHQVQ
TIQYSSSEDKDRKGVLQMKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGATQSFII
RPQKEGERALPSIPKLANSEKQGIRSHAVSVSEEKRGERKKEGRRELDIYETDDYAEIID
EEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGVYVTPENPAMAVAIKTCKNCTSD
SVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLAS
LILYAYQLSTALAYLESKRFVHRDIAARNVLVSSTDCVKLGDFGLSRYMEDSTYYKASKG
KLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGIKPFQGVKNNDVIGRIENGERLP
MPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLNTILEEEKLQQEERMRMESRRQVTVS
WDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQPNHYQVSGYPSSHGIPAMAGSIYP
GQTSLLDQTETWNHRPQEISMWQPNMEDSSSLDLRGIGQVLPTHLMEERLIRQQQEMEED
QRWLEKEERFLKPDVRLSRGSIDREDGSLQGPASNQHIYQPVGKPDHSAPPKKPPRPGAP
SHLGSLASLSSPVDSYNEGVKIQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKI
QPAPPEEYVPMVKEVGLALRTLLATVDETIPVLPTSTHREIEMAQKLLNSDLAELINKMK
LAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKSIGQSRPH
NT seq
3213 nt
NT seq
+upstream
nt +downstream
nt
atggcagcagcttacctagatccaaacttgaatcacactccgagttcaagcacaaagaca
cacctcagtactgggatggaacgatccccaggggccatggaacgagtcctgaaggttttc
cattactttgagaacaatagtgagccagcaacatgggcgagtattatacgtcatggggat
gcgacagatgtttggggcataatccagaagatagtggatagtcacaaagttaagaatgtc
gcctgttatggtttacggctcagtcacctgcagtcggaggaagttcattggctgcatcca
gatatgggagtgtccaatgtgagagagaagtttgaactgtctcatgctccagaggagtgg
aaatatgaactgcgaatccgatatttaccgaagggatttctgaaccagtttactgaagac
aagccaacattaaattttttctatcagcaggtgaaaaatgattacatggtagaaatagca
gaccaggtggaccaagaaattgccttgaagctaggttgccttgaaatccggagatcgtac
tgggaaatgcgaggcaatgcactagaaaagaagtccaactatgaagtattagagaaagac
gttggtttaaaaagattttttccgaagagtttgctggattcagtgaaggccaaaacactc
cgaaaattgatccagcaaacatttcgacagtttgccaacctcaatagagaagaaagtatt
ttgaaattcttcgagattctctcgccagtgtacagatttgacaaggaatgcttcaagtgt
gcccttggttcaagctggattatttcggtggagttggccattggtccagaagaaggaatc
agctaccttactgataagggttccaatccaacccacctggccgacttccatcaagtgcag
accattcagtattcaagcagtgaagataaggataggaaaggagtgctacagatgaaaatt
gctggagcaccagagcctctgacagtgacagcaccatccttaaccattgcagagaacatg
gccgatttgatagatggctactgccgactggtcaatggtgctacacagtcctttatcatc
aggcctcagaaagaaggagaaagagctttaccatccataccaaagctggccaacagtgag
aagcaggggatccgatcgcatgcagtctctgtatcagaggagaaaagaggagagaggaag
aaagaaggaaggagagaattagacatatacgaaacagatgattatgcagagattatagat
gaagaagacacttacaccatgccctcgaccagggattacgagattcagagagaacggatt
gaactgggacgctgcatcggtgaagggcagtttggagatgttcatcaaggagtttatgtg
accccagaaaaccctgctatggcagttgcaatcaaaacgtgtaaaaattgcacctcagac
agcgtgagagagaagttcttgcaagaagccttaacgatgcggcagtttgatcatccccac
attgtcaagttgatcggcgtcatcacagaaaaccccgtctggatcattatggagctgtgt
actctgggagagctgaggtcatttttgcaagtaagaaaatacagcttggatctggcatct
ctgatactgtatgcttatcaacttagcacagcgcttgcctacttggagagcaaaagattt
gtacatagagatattgctgctagaaatgtgctggtgtcctccaccgactgtgtgaaattg
ggtgactttggcttgtcccgatatatggaagatagtacgtattataaagcttccaaagga
aaactgcccatcaaatggatggcacccgaatccatcaacttccgacgttttacctcagcc
agtgacgtatggatgtttggtgtgtgtatgtgggagattctaatgcacggcatcaagccg
ttccaaggcgtgaagaacaacgacgtgattgggcgcattgagaatggcgagcggttaccg
atgccccccaactgccctcccacactgtacagccttatgaccaaatgttgggcttacgac
cccagcaggcggccaagatttacagaacttaaagctcagctcaatacgatactggaggaa
gagaagctgcagcaggaagaacgaatgagaatggaatcaaggcgacaagttaccgtgtcc
tgggattcggggggatcagacgaggctcctcccaagcccagtagacccggttatcccagc
ccaaggtccagtgagggtttttatcccagtccacagcacatggtacagccaaatcattac
caggtctcaggctaccccagttctcatgggattccagcaatggcaggtagcatttatcca
gggcagacttctctcttggatcagacagaaacctggaaccatcggcctcaggaaatctcc
atgtggcaacccaacatggaggattccagcagtttggacctgcgagggatagggcaggtt
ttaccaacacacctaatggaggagaggctgatacggcagcaacaagaaatggaggaagac
cagcgttggttggaaaaggaggaaagattcctgaagcctgatgtgcggctctctagaggc
agcattgatcgagaagatgggagtctccagggtccggcatctaaccagcatatttatcag
cctgtgggtaaaccagatcactctgccccgccaaagaagccacctcgcccaggagctccc
agccacttgggcagccttgccagtctcagcagccccgtggacagctacaacgaaggggtc
aagattcagccgcaagagatcagccctcccccgacagccaacttggatcggtccaatgac
aaggtgtatgagaacgtgactggcctggtgaaagctgtcatagagatgtccagcaaaatc
cagccagctccgccagaggagtatgtccccatggtgaaggaagttggtttagcactaagg
acccttctggccaccgtagatgagaccatcccagtgctccctacaagtactcacagggag
atcgagatggcccagaagctcctgaattctgacctggctgaactaattaacaagatgaag
ctggctcagcagtacgtcatgactagcctgcagcaggagtacaaaaagcagatgctcaca
gccgctcacgctctggctgtggatgccaagaacttgctggatgttattgaccaagccagg
ctaaaatccattggccagtccaggccccactaa
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