KEGG   Eublepharis macularius (Leopard gecko): 129335890
Entry
129335890         CDS       T09084                                 
Symbol
TPH2
Name
(RefSeq) tryptophan 5-hydroxylase 2 isoform X1
  KO
K00502  tryptophan 5-monooxygenase [EC:1.14.16.4]
Organism
emc  Eublepharis macularius (Leopard gecko)
Pathway
emc00380  Tryptophan metabolism
emc00790  Folate biosynthesis
emc01100  Metabolic pathways
Module
emc_M00037  Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin
Brite
KEGG Orthology (KO) [BR:emc00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    129335890 (TPH2)
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    129335890 (TPH2)
Enzymes [BR:emc01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.16.4  tryptophan 5-monooxygenase
     129335890 (TPH2)
SSDB
Motif
Pfam: Biopterin_H ACT TH_ACT
Other DBs
NCBI-GeneID: 129335890
NCBI-ProteinID: XP_054844717
UniProt: A0AA97JVB8
LinkDB
Position
9:complement(62047634..62140477)
AA seq 506 aa
MQPAMMMFSSKYWARRGLSLDSAVPQEHPLLGNVTVSTQNSFYLVSIFLQLNRTGSGKID
DKKGNKSTGKNESTSESGKTAVVFSLKNEVGGLVKALRLFQEKHVSMVHIESRKSKRRSS
EVEIFVDCDCSKKQFNELIQLLKYETNIVTLNPPENIWTDEEELDCVPWFPRKIAELDKC
SQRVLMYGSELDADHPGFKDNVYRQRRKYFVDVAMNYKYGQPIPRVEYTPEEIKTWGVVF
KELTKLYPTHACREYLKNFPLLTKYCGYREDNVPQLEDVSMFLKERSGFIVRPVAGYLSP
RDFLAGLAYRVFHCTQYIRHGSDPLYTPEPDTCHELLGHVPLFADPKFAQFSQEIGLASL
GASDEDVQKLATCYFFTIEFGLCKQDGQLRAYGAGLLSSIGELKHALSDKANVKTFDPKT
TCLQECLITTFQEAYFVSESFEEAKEKMRDFAKSINRPFSVYFNPYTQSIEILKDTRSIE
NVVQDLRSDLNTVCDALSKMNRYLGI
NT seq 1521 nt   +upstreamnt  +downstreamnt
atgcagccagcaatgatgatgttctccagtaaatactgggcaagacggggactctccttg
gattcagctgtgccccaagaacacccacttcttggcaatgtaacagtaagtacccagaac
tccttctatcttgtatccatattcttgcagctgaacagaactggttctggtaaaattgat
gataaaaagggcaacaaaagtacaggcaagaatgaatcaacatcagaaagcggaaagact
gctgtggtgttttctttgaaaaatgaagttggtggcttggtaaaagcacttcgactcttc
caggagaagcatgtgagcatggttcatattgaatcaagaaaatccaagaggaggagttca
gaggtagaaatttttgtggattgtgactgcagcaaaaaacaattcaacgaactcattcag
ttattaaaatacgaaactaacattgtaactttgaatccaccagaaaatatctggactgat
gaggaagaacttgactgcgtgccttggttccccaggaagattgctgaattagacaaatgt
tcccaaagagttctcatgtatggctctgaactggatgcagatcaccctggatttaaagac
aatgtctatcgacagagaagaaaatattttgtagatgttgccatgaactataaatatggc
cagccaatccctagagtggaatatacccctgaagaaataaaaacttggggtgtcgtgttc
aaagaacttactaaactgtatcctactcatgcttgtcgagaatatttgaagaatttccct
ttgctgaccaagtactgtggctacagagaggataatgtccctcaactggaagatgtttca
atgtttcttaaagaaagatctggcttcatagtgagaccagttgctggatatttgtcacct
cgagacttcctagcaggccttgcttatagagttttccactgtacccaatatatacgtcat
ggatcagatcccctctacactccagaaccggatacgtgtcatgaactcctgggacatgtg
cctctctttgctgaccctaaatttgcccagttttcccaggagattggactggcctcactg
ggagcatctgatgaggatgtccagaaacttgccacttgctattttttcaccattgagttt
ggcctttgtaagcaagatgggcaacttcgggcttacggggcaggccttttgtcttccatt
ggagaacttaagcatgctttgtctgataaagccaatgtgaaaacatttgatcccaagaca
acctgtttgcaagaatgccttatcactactttccaggaagcttactttgtctcagaaagt
tttgaagaagctaaagagaagatgagggactttgcaaaatcaatcaaccgtcccttttct
gtatatttcaacccgtatacccaaagcattgaaattctgaaagacaccagaagtattgaa
aatgttgttcaagatcttcggagtgacctgaacacagtgtgcgatgctttaagcaaaatg
aaccgatatttggggatatga

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