Eublepharis macularius (Leopard gecko): 129339088
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Entry
129339088 CDS
T09084
Symbol
BRCA1
Name
(RefSeq) breast cancer type 1 susceptibility protein
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
emc
Eublepharis macularius (Leopard gecko)
Pathway
emc03440
Homologous recombination
emc03460
Fanconi anemia pathway
emc04120
Ubiquitin mediated proteolysis
Brite
KEGG Orthology (KO) [BR:
emc00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
129339088 (BRCA1)
09124 Replication and repair
03440 Homologous recombination
129339088 (BRCA1)
03460 Fanconi anemia pathway
129339088 (BRCA1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
emc01009
]
129339088 (BRCA1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
emc04121
]
129339088 (BRCA1)
03036 Chromosome and associated proteins [BR:
emc03036
]
129339088 (BRCA1)
03400 DNA repair and recombination proteins [BR:
emc03400
]
129339088 (BRCA1)
Enzymes [BR:
emc01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
129339088 (BRCA1)
Protein phosphatases and associated proteins [BR:
emc01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
129339088 (BRCA1)
Ubiquitin system [BR:
emc04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
129339088 (BRCA1)
Multi subunit type E3
BRCC complex
129339088 (BRCA1)
Chromosome and associated proteins [BR:
emc03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
129339088 (BRCA1)
DNA repair and recombination proteins [BR:
emc03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
129339088 (BRCA1)
BRCA1-A complex
129339088 (BRCA1)
BRCA1-B complex
129339088 (BRCA1)
BRCA1-C complex
129339088 (BRCA1)
BRCA complex
129339088 (BRCA1)
FA (Fanconi anemia) pathway
Downstream FA components
129339088 (BRCA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BRCT_assoc
BRCT
zf-RING_UBOX
zf-C3HC4
zf-C3HC4_2
zf-C3HC4_4
BRCT_2
zf-RING_2
zf-Nse
zf-C3HC4_3
RING_XB3-XBAT31
zf-RING_5
zf-rbx1
U-box
zf-RING_6
zf-ANAPC11
zf-RING_10
Prok-RING_4
Motif
Other DBs
NCBI-GeneID:
129339088
NCBI-ProteinID:
XP_054849665
UniProt:
A0AA97LB41
LinkDB
All DBs
Position
12:32496009..32568020
Genome browser
AA seq
1699 aa
AA seq
DB search
MEEAMDSSGPGVTEVHGILLAMQKNLECPICLEVMKEPVSTQCAHVFCRFCILKLLEQKK
GIRRTKCPLCNANITRRTLREDVRFKLVIKGIWEAIGALECDTGFNLLQEKQIIIESKGY
RDRQNGAKNGEKRNRALQGKSSNLSLPNRTVTRCSLRKKSNANKTVCFEIGSDSSEDPFQ
KTGTIRCMGLRSSSRSKDSERHAEKRSRSPCHMELQEPSAEDVVLLGTPGTCGLSEARAG
STEGLQTSTGNVDDVEENAALEKRQNLSFPVPCMRRRSRRLVSSSTQEGGCSSLLGMEQY
QLAGEATNSAANKQAGIKAETVSIVQPAGSTQICNLVCEDQQELTQPQASPNSPLSQVSG
KKLKQSIQKVNEWFSKTKILSPTTLQDSHTEEGDPDLSPCLSDADSHVSQKTELREDQWE
VTAECDVGRALPKPVASKMVVDKIFGRTYKRARKCNPIYNPRDIIHIPAEELCSAMNTKS
CDTTIRKISALPKATLEQSSEDIMKKQTVPEDSEGPVDDVNAVLEEDGHDLTVVGETPGA
ELRAAELPVRERASSCASDASPISCHSCSLQNLKTARDSLSNISRRPVRQVCALQLAMCG
SSGSPDKTQAQAHSNPSSERPREARTEEMHIRRSKRLMSRVGGEQRRSEPAEKRRKQLEE
GEKKQKESQAENASPSLAADGPSVLQGRQAGLAGDASKACAFSDEKGSPSVEHPTESYNP
RPIVPDSGSQASCSLLQYHLAEFEQTDLRGKECTVAPQAEQSALCAQAPEGNEFCLGDVK
ESCTTPRAIENCELNPGTEDSELDTGFMWKILHRCKRQSFLLYPAPVKKSVAGTQMDLSV
DQVEGSEAVRVKKSNPGIDRVSEETGEAVTGRVANGHPGLSLISHPSPSSEHKSGSGHLQ
VASQALFPDSSCMPVAANEAKSGNPLWRQKPRNDKKESLEMEKTTNTNSCSCRSSGPWRS
GNFLGTSLHPTDETRSKAAHCLEMRPNSIDNKALTCISCPELSLPVACQRCPSESSSGSV
EKKSRVGEQRRLKGTGEQTVQMLSTGVSGGHLDQSPKDETPDFPLLSDTPEGLLGPATKS
KGCSLNGERDQQETLAMFAETDQVSPHERDLECSSSSSGSRPEGLVQARRRRVQKLSSSS
EENSSEDEELPCFQALVFGRSASTPSQAVKEEEEASADILAQKSSRQSGPRSRSEGGSPS
QESECSVNLFSSQSCDSVESTGKSCDARPLTPVPTSQGKVVTSRTVAEPLGEISRDAGQL
RDGHQDGINAAPNLGEALGYDSEASHLGDSSGFSSQSEILTTQQKDIMQNNLKKLQEEMA
VLEAALKEGGQDAAAEGSPLPSEERGLASSENQKTSPWDCASSDGLPVTPESPVHTKSPD
PAVQQGHEPGSASNLRRGSKQSLFSASSPAGNTHRTPDDNSTSSSTSQEHVARCLATKPE
RESPIAIQDKSSPPEHESQGRPVSSFDAATVCSGRKRKPKSLLLTSKRSMSLVASGLFPD
ELRLVQKFARKTRSTWSATISDDTTHVVMKTDEDLVCERTLKYFLGIAARKWVVSYQWIL
QSLKEGRVLNEGDFEVRGDIISGRNHQGPKKARESSAGKLFQGLEICCYGPFTDMQKEQL
EWMVELCGASLVKQPHLFSRSTNSVDAVVVIQPDAWLEDTGCPGIPPPCRATVVAREWVL
DSVSCYQCLAFNEYLVQQV
NT seq
5100 nt
NT seq
+upstream
nt +downstream
nt
atggaagaagccatggattcctctggtccaggtgttactgaggttcatgggatactgctg
gccatgcagaagaacttggaatgcccaatatgcctagaggtgatgaaagaaccggtctca
acacaatgcgctcatgtcttctgcaggttttgcatattgaagcttcttgagcaaaagaaa
ggtatccgcagaacaaagtgtccgctctgcaatgccaacataactcgaagaactttacgg
gaagatgtccgattcaagctagtaatcaaagggatatgggaagccattggtgctttagaa
tgtgatacaggattcaatttactgcaggaaaagcagatcatcattgaaagtaaaggctac
agggacagacagaatggagcaaagaacggagaaaagagaaaccgagccttgcagggcaaa
agctccaatttgtcacttcccaatagaactgtcacaaggtgctccctgagaaagaaaagc
aacgccaataaaactgtctgctttgaaattgggtcagactcatctgaagatccttttcag
aagactggcacaatcaggtgcatgggtctgagaagcagctctcggtctaaagatagtgaa
aggcatgctgagaagcgaagccgaagcccgtgtcacatggagctccaggagccaagtgcg
gaagatgtggtgctgttgggcaccccaggtacatgtggtttgtcagaggcaagagcggga
agcacagaaggccttcaaacgagcacaggaaatgtggatgatgttgaggagaatgcggct
ttggagaagaggcagaatttgtcttttccagttccctgcatgcggagacgtagcaggcgg
ctggtctccagttccactcaggagggtggctgttcctctctacttggcatggagcaatac
cagttggccggtgaagccacaaattctgccgcaaataagcaagcaggtattaaggcagaa
acagttagcatcgtgcagcctgctggaagtacgcaaatctgcaacctcgtgtgtgaagat
caacaagagctgacacagccccaggcttcccccaacagtcctttgagtcaggtctctggg
aagaaactgaagcagagcatccagaaagtcaatgagtggttttcaaaaaccaagatcctc
tctcccaccactttgcaggattctcacactgaggaaggggatccagatctgagcccatgc
ttgtcagatgcggactctcatgtctcccaaaagactgaactgagggaagaccagtgggag
gtcacagcagagtgtgatgttggcagggctctgcccaaacctgttgcttccaaaatggta
gtagataaaatatttgggagaacatacaagagggcacgcaagtgcaaccccatttacaat
ccgagggatataattcatatcccagcagaagaactctgcagtgctatgaacactaaatcc
tgtgacaccaccataaggaaaatctcagccctgccaaaggccacattggagcagtcatct
gaggacattatgaaaaagcaaactgtgccagaggacagcgaggggcccgttgatgatgta
aatgctgttttggaagaagatggccacgatcttactgtggtgggtgaaactcctggggct
gagctaagggcagcagaactccctgttagggaaagggcatccagttgtgcatcagatgcc
tctcctattagctgccactcgtgcagcttgcaaaatctgaagacggcaagggactctttg
agcaatataagccggcgaccagtcaggcaagtctgtgcactgcagttagcaatgtgtgga
agctctgggtcacctgacaagacccaggcacaggcacacagcaacccaagcagtgagcgg
ccgagggaagcccgcacagaagagatgcacatcaggcgcagcaaaaggcttatgtcgcgg
gtaggaggagagcagaggaggagtgagccagcagagaaacgaaggaagcagttggaggag
ggagaaaagaagcaaaaggagtcccaggcagaaaacgcatccccttcactagcagcggat
ggccccagtgtgttgcagggtaggcaggcaggcctggcaggtgatgcaagtaaggcgtgt
gccttttctgatgagaagggttctccgagtgttgaacaccctacagagagctacaatcct
cgtcccattgtccctgactctggctcccaagccagttgctcgctgctgcagtatcatctt
gcagagttcgaacaaactgatcttaggggcaaagagtgcacagtagcacctcaagccgaa
cagagtgccttgtgtgcccaggccccagaggggaatgaattttgcttgggggatgtgaag
gaaagctgcacgactcccagagcaatagagaattgcgagttaaatccaggaactgaggac
agtgaactggatacaggtttcatgtggaagatactccaccgctgcaagcgccagtcattc
ttgttgtatccagctccagtaaagaaatctgttgcaggaacccagatggatctcagcgtt
gaccaggtggaaggcagcgaggccgtccgtgtgaagaaatcaaatccaggcatagacaga
gtgagtgaggagacaggagaagcagtcactggcagggtggccaacggccaccctggcctg
agtctgatatctcatccgtccccttcttctgagcataagagtgggtctggccatctccaa
gttgcttcacaagctctcttcccagatagctcatgcatgccagtagctgctaatgaggcc
aagagtggaaatccactgtggagacaaaagcccagaaatgacaagaaagagtccttagaa
atggagaaaacaacaaatacaaacagctgtagctgcagaagctcaggtccctggagaagt
ggcaacttcctaggcacaagtttacatcccactgatgagaccagatccaaggcagcccat
tgtttagaaatgagaccaaatagtatcgataacaaagctttgacctgcatctcctgtcca
gaactgtcacttcctgttgcttgtcagcgctgcccttctgaatccagcagtggcagcgta
gaaaagaaaagcagagttggggaacaaagacgactaaagggcactggggaacaaactgtc
cagatgctcagcacaggtgtttccggagggcatttggaccaatctcccaaggacgagact
cctgacttcccgttgttatcagatacacccgagggcttgctgggccctgccaccaaaagc
aaagggtgctcgcttaatggggaaagggaccaacaggaaaccttggccatgtttgctgaa
actgaccaggtctctccccatgagagggatctagaatgcagcagcagcagttcaggatca
aggcctgaaggcctggttcaggcacgccgaagacgggtgcagaagctgtcttcctcctca
gaagaaaattccagtgaagatgaggagttgccgtgctttcaagcgctggtatttggtcgg
tcggcaagcacaccatcgcaggcagtgaaagaggaggaggaggcatcagcagacattcta
gcccagaagagcagcaggcaaagcggccccagatcccggagtgagggtggctctccaagc
caggagtcggagtgttctgtgaacttgttttcctctcagtcatgtgactctgtggaatcc
accggaaagtcttgtgatgcaagacccttaacaccagttcccacttcccaaggaaaggtg
gtgacttccagaacagtcgctgaacccctgggcgaaatctccagagatgctgggcaactg
agagacggacatcaagacggcataaatgcagcacccaatttaggtgaagctttgggttat
gacagtgaagctagccacctgggggattcatcaggcttctcctcacagagtgagatcctc
accacacagcaaaaagacattatgcagaacaacttaaagaagctccaggaagagatggct
gtgcttgaggcagccctgaaggagggaggccaggatgctgctgcagaagggtcgccattg
ccaagtgaggaaaggggattagcaagttctgaaaatcagaaaacaagcccctgggattgt
gcctcatctgatggattgccagtgacaccagaaagtcctgtccacaccaaaagtccagat
ccagcggttcaacaaggtcatgaaccaggaagtgcaagtaatttgagacgtggaagcaag
caaagcctcttcagtgcctcctcccctgctggaaacacgcacaggactccggatgataac
tccacatcttcctcaacatctcaagaacatgttgcacgttgtctggcaaccaagccagaa
agggaatctcctattgctattcaggacaaatcaagccctccagaacacgagtcccagggg
aggccagtctcttccttcgatgcagccacagtttgtagtggtagaaagaggaagcctaag
agtctgcttttgacaagtaagaggagtatgtctctggtggcatcgggtctattcccggat
gagctgcgactggttcagaagtttgccaggaaaaccaggagcacttggtctgctaccatt
tctgatgacacaacccatgttgtaatgaaaactgatgaagatctggtttgtgagcggacc
ctgaagtatttccttggcattgcggcacggaaatgggtggtgagctaccagtggattcta
cagtcactgaaagaaggaagggtccttaatgaaggggactttgaagtaagaggagacata
atcagtgggagaaatcatcaagggcccaaaaaagcaagggaatcttctgctggaaagctt
ttccaaggcttggaaatttgctgctatgggcccttcacagacatgcaaaaagaacaacta
gaatggatggtcgaattgtgtggcgcctcccttgtgaagcaacctcacttattctcacgc
tcaacaaactctgtggatgctgttgtggtcattcagcctgatgcttggttggaagacact
ggctgcccaggaatcccacccccctgccgtgctactgtagtggcccgtgagtgggtgctg
gacagcgtttcatgctaccagtgcctggcatttaacgaataccttgtgcagcaggtgtga
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integrated database retrieval system
