KEGG   Enterobacter cloacae subsp. dissolvens SDM: A3UG_01355
Entry
A3UG_01355        CDS       T02159                                 
Symbol
metH
Name
(GenBank) B12-dependent methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
enl  Enterobacter cloacae subsp. dissolvens SDM
Pathway
enl00270  Cysteine and methionine metabolism
enl00450  Selenocompound metabolism
enl00670  One carbon pool by folate
enl01100  Metabolic pathways
enl01110  Biosynthesis of secondary metabolites
enl01230  Biosynthesis of amino acids
enl04981  Folate transport and metabolism
Module
enl_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:enl00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    A3UG_01355 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    A3UG_01355 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    A3UG_01355 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    A3UG_01355 (metH)
   04980 Cobalamin transport and metabolism
    A3UG_01355 (metH)
Enzymes [BR:enl01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     A3UG_01355 (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: AFM58024
LinkDB
Position
289120..292803
AA seq 1227 aa
MSSKVEQLRAQLNERILVLDGGMGTMIQSYRLSEDDFRGERFADWPCDLKGNNDLLVLSK
PQVIADIHNAYFEAGADIVETNTFNSTTIAMADYQMESLSAEINFEAAKLARACADAWTA
RTPEKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDQLVAAYRESTKALVEGGSDLILI
ETVFDTLNAKAAIYAVKEEFEALDVDLPIMISGTITDASGRTLSGQTTEAFYNSLRHAEA
LSFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAAQIREWAE
SGFLNIVGGCCGTTPEHIAAMSNAVAGLPPRKLPELPVACRLSGLEPLTIGDDSLFVNVG
ERTNVTGSAKFKRLIKEEKYSEALDVARQQVENGAQIIDINMDEGMLDAEAAMVRFLNLI
AGEPDIARVPIMIDSSKWEVIEKGLKCIQGKGIVNSISMKEGVDIFIHHAKLVRRYGAAV
VVMAFDEVGQADTRERKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQ
DFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAG
QLAIYDDLPAELRDAVEDVILNRRNDATERLLDLAEKYRGSKADDAANVQQAEWRAWDVR
KRLEYSLVKGITEFIEQDTEEARQQAARPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVK
SARVMKQAVAYLEPFIEASKEQGSSNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIIDL
GVMVPADKILRTAREVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKA
HTAVKIEQNYSGPTVYVQNASRTVGVVSALLSDTQRDDFVARTRKEYETVRIQHARKKPR
TPPVTLQAARDNDLAFDWASYTPPVAHRLGVQEVSASIETLRNYIDWTPFFMTWSLAGKY
PRILEDEVVGEEAKRLFNDANDMLDKLSAEKTLNPRGVVGLFPANRVGDDIEIYRDETRT
HVLTVSHHLRQQTEKVGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAFEAQH
DDYNKIMVKAIADRLAEAFAEYLHERVRKVYWGYAANENLSNEELIRENYQGIRPAPGYP
ACPEHTEKGTIWQLLDVEAHTGMKLTESFAMWPGASVSGWYFSHPDSKYFAVAQLQRDQI
EDYALRKGMSVSEVERWLAPNLGYDAD
NT seq 3684 nt   +upstreamnt  +downstreamnt
gtgagcagcaaagtagagcaactgcgtgcgcagttaaatgaacgaattctggtgctggac
ggcggcatgggcaccatgatccagagctatcgtctcagtgaagacgatttccgcggcgaa
cgtttcgcggactggccatgcgacctcaaaggtaacaacgacctgctggtgttaagcaaa
ccgcaggtgattgcggatatccacaacgcctacttcgaggcgggtgccgatatcgttgaa
accaacacctttaactcgacaaccatcgccatggcggattaccagatggagtccctgtcg
gcggagataaactttgaggcggcgaaactcgcccgcgcctgtgccgacgcatggacggcc
cgcacgccggagaaaccgcgctatgttgccggggtgctgggtccaaccaaccgcaccgcc
tctatttcaccggacgtgaacgacccggcgtttcgtaatattacctttgaccagctggtt
gcggcctaccgtgaatcaaccaaagcgctggtggaagggggttccgatctgatcctgatt
gaaacggttttcgataccctcaatgccaaagccgcgatatacgcggtgaaagaggagttc
gaggcgctggacgttgacctgccgatcatgatttccggcaccatcaccgatgcctctggc
cgtaccctgtcaggccagaccaccgaagcgttttataactccctgcgccacgctgaagcg
ctctccttcggcctgaactgcgcgctggggccggatgaactgcgccagtacgtgcaggag
ctgtcgcgcatcgcggaatgctacgttaccgcccacccgaacgccggactgccaaacgcc
tttggcgaatacgacctggatgcggacaccatggcggcgcaaatccgcgaatgggctgaa
tccggtttcctgaatatcgttggcggctgctgcggcaccacgccggagcacatcgccgcc
atgagcaatgccgtggccggtctgccgccgcgtaaactgcccgagctgccggttgcctgc
cgtctctccggccttgaaccgttgaccatcggcgatgacagcctgtttgtgaacgttggg
gagcgtacaaacgttacgggctcggcaaagttcaaacgactgatcaaagaagagaagtac
agcgaagcgctggacgttgcccgccagcaggttgaaaacggcgcgcagatcatcgacatc
aacatggatgaggggatgctcgacgccgaagcggcgatggtgcgtttcctcaacctgatc
gctggtgagccggatatcgcccgcgtgccgatcatgattgactcctccaaatgggaagtc
atcgaaaaagggctgaagtgcattcagggcaaaggtatcgtcaactccatttcaatgaaa
gaaggcgtcgatatcttcattcaccatgcaaagctggtccgtcgatatggcgcggccgtg
gtggtgatggcctttgatgaagtgggccaggccgatacccgcgagcgcaaaatagaaatt
tgccgccgcgcgtacaagatactgactgaagaggtgggcttcccgccggaagacattatc
ttcgacccgaacatcttcgccgttgcgaccgggattgaagagcacaataactacgcccag
gactttatcggcgcgtgtgaagacatcaaacgtgagctgccgcatgcgctgatctccggc
ggcgtgtcgaacgtgtcgttctcgttccgcggcaacgatccggtgcgtgaagcgatccac
gccgtattcctctattacgccattcgcaatggaatggacatggggatcgtcaacgccgga
cagctggcgatttacgacgaccttcctgccgaactgcgcgatgccgtagaggacgtgatc
ctgaaccgccgcaacgacgccaccgagcgactgctcgatctggcagaaaaataccgcggc
agcaaagcggacgacgctgccaatgttcagcaggccgagtggcgtgcctgggatgtaagg
aaacggctggaatattcgctggtaaaaggcatcaccgagtttatcgagcaggataccgaa
gaggcacgtcagcaggccgcacggcccatcgaggttatcgaagggccgctgatggacggc
atgaacgtggtcggcgatctgttcggcgagggcaaaatgttcctgccgcaggtggtgaaa
tctgcgcgcgtgatgaagcaggccgtggcgtatctggagccgtttatcgaagccagcaaa
gagcaaggttccagcaacggtaaaatggttatcgccaccgtgaagggcgacgtgcatgac
atcggaaagaacatcgtcggtgtggtgctgcagtgcaataactacgagattatcgatctt
ggcgtgatggtgccggcggataaaatcctcaggaccgcgcgcgaagtcaatgctgacctg
attggcctttccgggctgattaccccgtcgcttgacgagatggtcaatgtggcgaaagag
atggagcgtcagggcttcaccattccgctgctgatcggcggggcgaccacctcgaaagcg
cacacggcggtgaaaatcgagcagaactacagcggcccgacggtctatgtacagaacgcc
tcgcgcaccgtgggggtggtctctgcgctgctctccgacacccagcgcgatgactttgtg
gcacggacccgcaaagagtacgagaccgtccgcattcagcatgcacgcaaaaaaccgcgc
accccgccggtgacgctgcaggcggcgcgcgataacgatctggcgtttgactgggcgagc
tatacgccgccggttgcccatcgtctgggcgtgcaggaggtgagcgccagcattgaaacg
ctgcgcaactacatcgactggacgccgttctttatgacctggtcgctggcgggcaaatat
ccgcgcatccttgaagatgaggtagtaggtgaagaggcgaagcgcctgtttaacgatgcc
aacgacatgctcgacaagctgagcgcagagaaaaccctcaacccgcgcggcgtggtgggg
ctgttcccggcgaaccgtgtgggcgatgacatcgaaatttatcgcgatgagacgcgcact
cacgtgctgaccgtaagccatcacctgcgccagcaaactgaaaaggtcgggtttgccaac
tactgtctggccgattttgttgcgccgaagctgagtggtaaagccgactacatcggtgcc
ttcgctgtgaccggcggtctggaagaggatgcgctggcggacgcctttgaagcgcagcac
gatgattacaacaaaatcatggtcaaagcgattgccgatcgcctggcggaagccttcgca
gagtatctgcacgagcgcgtgcgtaaggtgtactggggatacgcggcgaatgaaaatctc
agcaatgaggagctgatccgcgaaaactaccaggggatccgcccggcgccgggttacccg
gcctgtccggagcataccgaaaagggcaccatctggcagctgctggacgttgaagcccat
accgggatgaaactgaccgaatctttcgcgatgtggccaggggcatcggtttccggctgg
tacttcagtcatccggacagcaagtacttcgccgtggcgcagctgcagcgcgatcagatc
gaagattatgcactgcgtaaaggcatgagcgtctctgaagtggaacgttggttagcgccg
aatctcggctacgacgccgactga

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