KEGG   Euhalothece natronophila: FRE64_08160
Entry
FRE64_08160       CDS       T06117                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
enn  Euhalothece natronophila
Pathway
enn00270  Cysteine and methionine metabolism
enn00450  Selenocompound metabolism
enn00670  One carbon pool by folate
enn01100  Metabolic pathways
enn01110  Biosynthesis of secondary metabolites
enn01230  Biosynthesis of amino acids
enn04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:enn00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    FRE64_08160 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    FRE64_08160 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    FRE64_08160 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    FRE64_08160 (metH)
   04980 Cobalamin transport and metabolism
    FRE64_08160 (metH)
Enzymes [BR:enn01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     FRE64_08160 (metH)
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: QDZ39919
UniProt: A0A5B8NP05
LinkDB
Position
1713914..1717522
AA seq 1202 aa
MTTTKTKVKSAFLERLHSPERPVLVFDGGMGTSLQRQELTLEDFGSATLEGCNEYLVKSK
PEAIEQVHREFLEAGADVIETDTFGSSSVVLAEYDIPEQAYELSKMAAELAKRVAKEYST
PEKPRFVAGAMGPTTKLPTLAHIDFDTMKESYREQAAGLYDGGVDLFIIETCQDVLQIKC
ALNAVEELFEEKGDRIPIMVSITMEVMGTMLVGTEIDAALTILEPYNIDILGLNCATGPD
KMKEHIKYLSEHSPFPISCIPNAGLPENVGGQAHYKLTPMELRMALMHFVEDLGVQIIGG
CCGTRPDHIEQLADIAKDLKPAERHPKKEVAAASIYSTQNYIQDNSFLIVGERLNASGSK
KTRTLLNEEDWDGLVSIAKSQVKEGAHILDVNVDYVGRDGERDMYEVVSRLVNNVTLPLM
VDSTEWTKMEVGLKVAGGKCLINSTNYEDGEERFFKVLELGKKYGAGVVIGTIDEDGMAR
TAQKKFEIAQRAYRQAVEYGIPPYEIFFDPLALPISTGIEEDRVNGKETMESIKMIRENL
PECHIMLGVSNLSFGLNSAARVALNSVFLHDAVEAGMDAAIVSASKIVPLAKIEEEHKQV
CRDLIYDRRQFNEDGICTYDPLTKLTELFAGKKAEVAGSSMENLSIEEKLKQHIIDGERI
GLNDVLDEAMNTYPPLDIINKFLLDGMKVVGERFGAGEMQLPFVLQSAETMKAAVAHLEP
HMEKDDAGDNAKGTVVIATVKGDVHDIGKNLVDIILSNNGYRVINIGIKQTVDNIIAAYR
EHNADCIAMSGLLVKSTAFMKDNLETFNEEGITVPVILGGAALTPKFVYGDCQEAYNGKV
VYGKDAFSDLNFMDKLMPAKEAGQWDDLQGFLGEFAEEEEEGKAVKAKAKKEKAESNGAA
EEEDGKAEEPQVVDTRRSEAIEVDVERPTPPFWGYKLLNPDDIPYDEMLWYLDKQALFAG
QWQFRKKKSQSREEYDQFLQETVEPILAEWKQRAKEENLLHPQLIYGYFPCYAQGNTLHL
FDPKLMEEKGTIPEGSEPIASFEFPRQGSGQRMCIADFYAPKESGMIDVFPMQAVTVGEI
ATEYAKELFAQDKYTDYLYFHGFGVQAAEALAEWGHALIRKELGFGDEDPDNIRDILAQR
YRGSRYSFGYPACPNIQDQYALLDLLEAKQINLYMDESEQLYPEQSTTAIVSHHPKARYF
SA
NT seq 3609 nt   +upstreamnt  +downstreamnt
atgacaactactaaaacaaaagtaaaaagcgcatttttagagcgtcttcactcaccagag
cgtcccgttctcgtctttgacggcggaatgggaacttccttacagagacaagaattaacc
ttagaagactttggcagtgccaccctagaaggctgtaacgaatatctggttaaatcaaaa
ccagaagccattgaacaagtgcatcgggaatttttagaagccggggctgatgtgattgaa
accgacacctttggttctagttccgtggttttggcggaatatgatattcctgagcaagcc
tacgaactcagtaaaatggcagcggaacttgcgaagcgagtggcaaaagaatattccact
cccgaaaaacctcgctttgtcgctggtgcaatggggccaactaccaaactccccaccctt
gctcatatcgactttgacaccatgaaagagtcctaccgtgaacaagcagccgggctttat
gatgggggggttgacttatttatcattgaaacctgccaagatgttcttcaaatcaaatgt
gctctcaacgcagtagaagaactctttgaagaaaaaggcgatcgaattcccatcatggtt
tctatcacgatggaagtcatgggaaccatgctagtgggaacagaaattgacgcagcttta
accatcctcgaaccctataacattgatattttagggcttaactgcgccactggccccgac
aaaatgaaagaacacattaaatacttgtcggaacattctccttttcccatctcctgtatc
cccaacgcgggactaccagaaaacgttggtggacaggctcattataagctcactcctatg
gagctacggatggcgctaatgcacttcgttgaagacttgggtgtacaaattatcggaggt
tgctgtgggactcgtcctgaccatattgaacagcttgctgacattgccaaagatttaaaa
cctgccgaacgtcatccgaaaaaagaagtagctgccgcctccatttacagcactcagaac
tacattcaagacaactccttcctcattgttggagaacgtcttaatgccagtggctcgaaa
aaaacccgcaccctgcttaacgaagaagactgggacggcttagtatctatcgctaaatca
caggtcaaagagggagcgcacatccttgatgtcaacgtggactacgtggggcgtgacggt
gaacgggatatgtacgaagtggtttcacgtctcgtcaataatgtcacccttcctctgatg
gtggactccaccgaatggacaaaaatggaagtgggattaaaagtagctggtgggaaatgt
ctgattaactccactaactacgaagatggagaagaacgcttctttaaagttttagaacta
gggaaaaaatacggcgctggcgttgttatcggaacgattgatgaagacggaatggcgcga
actgcccagaagaaatttgaaattgcccaacgtgcttaccgtcaagcagtagaatatggc
attcctccttacgaaatcttctttgaccctctggctttacccatttccacagggattgaa
gaagaccgcgtgaatgggaaagagaccatggagtccattaagatgattcgggagaactta
cccgaatgtcatattatgcttggggtgtctaacctttcctttggtttaaactctgctgcc
cgagttgcccttaactctgtatttctccatgatgcagtagaagcaggaatggatgcggcc
attgtcagtgccagtaaaattgttcctctcgccaaaattgaagaagaacataaacaagtt
tgccgtgatttaatttatgaccgtcgtcaatttaatgaagatggcatttgtacttatgat
cccctcacgaaactaacagaactctttgctggtaaaaaagccgaagtggctggttccagc
atggaaaacctctccattgaggagaaattaaaacagcacatcattgatggggaacgtatt
ggcttaaacgatgttctcgatgaagccatgaatacttatccgcccttggatattattaat
aagtttctccttgatggcatgaaagttgtgggagaacgctttggtgctggagaaatgcag
cttccctttgtgttacagtccgcagaaacgatgaaagcggcggtggcgcatcttgaacct
cacatggaaaaagatgatgcaggggataatgcgaaaggaaccgttgtcattgccactgtt
aaaggagacgtacatgatattggtaaaaacttagtagatatcattctctctaataatggc
tatcgcgtcattaacattggcattaaacagacagtcgataatatcattgccgcttacaga
gaacataatgctgactgcattgccatgagtggactgttagtaaaatccactgcctttatg
aaggataatttagaaaccttcaatgaagagggcattactgttcctgtcattctcggtggc
gcggcgttaaccccgaaatttgtctatggtgactgccaagaagcctataacggcaaagtg
gtttacggaaaagatgccttctctgacctcaacttcatggataagttaatgccagcaaaa
gaggctggtcaatgggatgatttacaaggcttcttaggggagtttgctgaagaagaagaa
gaaggtaaagccgtcaaggcgaaggcgaaaaaagaaaaagccgaaagtaatggcgcagcc
gaagaggaagacggtaaagctgaagaaccgcaagtggttgatacccgtcgctcagaagct
atagaggtggatgttgagcgtccaacaccgccattctggggttataagttactcaatccc
gatgacattccttatgatgagatgctgtggtatctcgataagcaagccctgtttgctggt
caatggcagttccgcaagaagaaaagtcaatcgcgagaagaatatgatcaattcttacaa
gaaacggttgagccaattctcgcagagtggaagcaacgcgcaaaagaagaaaatctgttg
catccgcagttaatttatggctatttcccttgctatgcccaaggaaacaccttacatctg
tttgacccgaaattaatggaggagaagggaaccattcctgaaggcagtgaacccattgcc
agctttgaattccctcgtcagggttcaggacagcggatgtgtattgctgacttttatgca
ccaaaagagtcaggaatgattgatgtcttcccgatgcaggcggtaacggttggtgaaatt
gccactgagtacgctaaagaactgtttgctcaggataaatacactgattacctctatttc
cacgggtttggggtacaagccgcagaagctctcgccgaatggggacacgctctgatccga
aaagagttaggatttggtgacgaagaccccgataatattcgtgatattttagcgcaacgt
tatcgtggttctcgctatagctttggctatccagcttgcccaaatattcaggatcaatac
gccctgttggacttgttagaggcgaaacaaattaacctctacatggatgaaagcgaacag
ttgtatcctgagcagtcaacaacagcgattgtgtctcatcatccgaaagcccgttacttc
agtgcttaa

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