Enterobacter sp. R4-368: H650_16685
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Entry
H650_16685 CDS
T02700
Symbol
metH
Name
(GenBank) B12-dependent methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
enr
Enterobacter sp. R4-368
Pathway
enr00270
Cysteine and methionine metabolism
enr00450
Selenocompound metabolism
enr00670
One carbon pool by folate
enr01100
Metabolic pathways
enr01110
Biosynthesis of secondary metabolites
enr01230
Biosynthesis of amino acids
enr04980
Cobalamin transport and metabolism
enr04981
Folate transport and metabolism
Module
enr_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
enr00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
H650_16685 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
H650_16685 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
H650_16685 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
H650_16685 (metH)
04980 Cobalamin transport and metabolism
H650_16685 (metH)
Enzymes [BR:
enr01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
H650_16685 (metH)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
AGN86682
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Position
3311117..3314803
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AA seq
1228 aa
AA seq
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MSSKVEQLKQQLSKRILVLDGGMGTMIQSYRLSEQDFRGERFADWPCDLKGNNDLLVLSK
PEVISAIHDAYFAAGADIIETNTFNSTTIAMADYQMESLSAEINFAAAKLARASADKWTA
QTPDKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDQLVTAYRESTKALVEGGSDLILI
ETVFDTLNAKAAIFAVKAEFDALGVELPIMISGTITDASGRTLSGQTTEAFYNSLRHADA
LTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAVQIGEWAQ
AGFLNIVGGCCGTTPVHIAVMSRAVEGVPPRQLPEVPVACRLAGLEPLNIGDDSLFVNVG
ERTNVTGSAKFKRLIKEEKYAEALDVARQQVESGAQIIDINMDEGMLDAEAAMVRFLNLI
AGEPDIARVPIMIDSSKWEVIEKGLKCIQGKGIVNSISMKEGVEPFIHHAKLVRRYGAAV
VVMAFDEIGQADTRARKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQ
DFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAG
QLAIYDDLPTELRDGVEDVILNRRDDATERMLDLAEKYRGSKAADEGANAQQAEWRNWDV
KKRLEYSLVKGITEFIEFDTEEARQQAARPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVV
KSARVMKQAVAYLEPYIEASKEKGSSNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIID
LGVMVPADKILKTAREEKADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSK
AHTAVKIEQNYSGPTVYVQNASRTVGVVSALLSDTQHDEFVARTRKEYETVRIQHARKKP
RTPPVTLQAARENDLAFDWESYTPPVAHRLGVQEVTASIETLRNYIDWTPFFMTWSLAGK
YPRILEDEVVGEEAKRLFADANEMLDKLSAEKLLNPRGVVGLFPANRVGDDVEIYRDETR
TQVLTVGCHLRQQTEKVGFANYCLADFVAPKQSGKADYIGAFAVTGGLEEDALAQAYDAA
HDDYNKIMVKAVADRLAEAFAEYLHERVRKVYWGYAPNENLSNDELIRENYQGIRPAPGY
PACPEHTEKGTIWQLLDVEKHTGMKLTESYAMWPGASVSGWYFSHPDSKYFAVAQIQRDQ
VEDYARRKGMSVAEIERWLASNLGYDAD
NT seq
3687 nt
NT seq
+upstream
nt +downstream
nt
gtgagcagcaaagttgagcaactgaagcagcagttaagcaaaagaattctggttctggat
gggggcatgggcaccatgatccagagctatcgtctgagtgagcaggattttcgcggcgag
cgtttcgccgactggccctgcgatcttaaaggtaacaacgacttgctggtgctcagcaag
ccggaggtgataagcgcgatccatgacgcctactttgcggcgggcgcggatatcatcgaa
accaacacttttaactcaacgacaatcgccatggcggattaccagatggaatccctgtcg
gcggaaatcaacttcgctgctgccaaactggcgcgtgccagcgccgacaaatggacggcg
caaacgccggataaaccgcgttatgtcgcgggtgtgctcggcccgactaaccgcactgcc
tcaatctcaccggacgttaacgacccggcgtttcgcaatatcactttcgatcaactggtc
accgcttatcgcgaatccaccaaagcgctggtggaagggggatcggatctgatcctgatc
gaaaccgtgttcgatacgcttaacgccaaagcggcgatctttgcagtaaaagcggagttt
gacgcgctgggcgttgagctgccgatcatgatttccggcaccattaccgacgcctccggg
cgtacgctctccggccagaccaccgaagcgttttacaactctctgcgccacgccgatgcg
ctcaccttcggcctgaactgcgcgctggggccggatgaactgcgccagtatgtgcaggag
ctttcccgtatcgccgaatgctatgtcaccgcgcacccgaacgccggcctgcccaacgcc
tttggtgaatatgatctcgatgccgacaccatggcggtgcaaatcggcgagtgggcgcaa
gccggttttctgaacattgtcggcggctgctgcggtaccacaccagtgcatatcgccgtc
atgagccgcgcggtcgaaggcgtgccgccgcgtcagctaccggaggtgccggttgcttgc
cgtcttgcgggtctggagccgctcaacattggcgacgacagcctgtttgtaaacgttggc
gaacgtaccaacgtcaccggttccgccaaatttaagcgcctgatcaaagaagagaaatac
gccgaagcgctggacgtggcccgccagcaggtggaaagcggcgcgcagatcatcgacatc
aatatggatgaagggatgctcgacgccgaagcggcgatggtgcgtttcctcaacctgatt
gccggtgagccggacattgcccgcgtgccgatcatgatcgactcctcaaaatgggaggtg
atcgaaaaagggctgaaatgtatccagggtaagggcatcgttaactcaatttcgatgaaa
gagggcgttgagccatttattcaccacgcgaagctggtgcgtcgttatggcgccgccgtg
gtggtaatggcctttgacgaaatcggtcaggcggatacacgtgcgcggaaaatcgaaatt
tgccgtcgcgcctataaaattctgaccgaagaggtgggtttcccgccggaagacattatc
ttcgatccgaacatcttcgccgtagcaacgggtattgaagagcacaataactacgcgcag
gactttatcggcgcgtgtgaagatatcaaacgcgaactgccgcatgcgctgatttctggc
ggtgtttccaacgtttcgttctcgtttcgcggcaacgacccggtgcgtgaagcgatccac
gccgtgttcctttattacgccattcgtaacggcatggacatgggcatcgtcaacgccgga
caactggcgatttacgatgatttgcctaccgagctgcgcgacggcgttgaggatgtgatc
cttaaccgccgcgatgatgcgaccgagcgcatgctggatctggcggaaaaataccgcggc
agcaaagccgccgatgaaggggcgaacgcgcagcaggcggagtggcgcaactgggatgtg
aaaaaacgtctcgaatattcactggtaaaaggcatcaccgaatttatcgagttcgatacc
gaagaggcgcgtcagcaggccgctcgcccgatcgaggtgatcgaagggccgttaatggac
ggcatgaacgtggtgggcgatctgttcggcgagggcaaaatgttcctgccgcaggtggtg
aaatccgcccgcgtgatgaaacaggccgtggcgtatctggaaccgtatatcgaagccagc
aaagagaagggcagcagcaacggcaaaatggtgatcgccactgtgaaaggcgatgtccac
gacatcggcaaaaatatcgtgggcgtcgtgctgcaatgcaacaactacgaaattatcgac
ctcggcgtgatggtgcccgccgataaaatcctgaaaactgcccgcgaagagaaggctgac
ctgattggtctttccggattgattacgccgtcgctcgacgaaatggtcaacgtggcgaaa
gagatggaacgccaggggttcaccattccgctgctgattggcggtgcgaccacatcgaaa
gcgcacacggcggtgaaaatcgaacagaactacagtgggccgacggtgtatgtgcaaaac
gcctcgcgtaccgtaggtgtggtgtctgctctgctttcggatacgcagcacgatgagttt
gttgcccgtacccgcaaagagtatgaaaccgtacgtatccagcatgcgcggaaaaaaccg
cgtacgccgccagtgacgttgcaggccgcacgggagaacgatcttgcgtttgactgggaa
agttatactccgccggtcgcgcatcgcctgggcgtgcaggaagttactgccagcatcgag
acactgcgcaattacatcgactggacaccattctttatgacctggtcgctggccgggaaa
tatccgcgcatccttgaagatgaggtggtgggggaagaggcgaaacgtctatttgccgat
gccaacgagatgctcgataaactgagcgcggaaaagctgctcaacccgcgcggcgtggtc
gggcttttcccggctaatcgcgttggcgacgatgtcgaaatctaccgcgacgaaacccgc
acgcaggtactgacagtaggttgccatctgcgccagcaaacggaaaaagtcggttttgcg
aactactgcctggcggattttgtcgcccccaaacagagcggcaaagcggactacattggc
gcattcgcagtgacgggcggtcttgaagaggacgcgttagcacaagcgtatgacgccgcg
cacgatgattacaataaaatcatggtgaaagcggtggccgatcgcctggcggaagccttt
gcggaatacctgcatgagcgggtgcgcaaagtgtactggggctacgcgccgaacgaaaac
ctcagcaacgatgagttgatccgcgaaaattatcagggcattcgcccggcaccgggctat
ccggcttgtccggagcacacggaaaaaggcaccatctggcagttgctggacgttgaaaaa
cataccgggatgaaactgaccgaatcctacgcgatgtggccaggggcatcggtttccggc
tggtatttcagccacccggacagtaaatatttcgcggtagcgcaaattcagcgtgaccag
gtagaagattacgcgcggcgtaaaggcatgtcggtggcggaaattgagcgctggctggcg
tctaatttaggttacgacgcggattaa
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