KEGG   Escherichia coli O55 H7 CB9615 (EPEC): G2583_0050
Entry
G2583_0050        CDS       T01190                                 
Symbol
folA
Name
(GenBank) Dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
eok  Escherichia coli O55:H7 CB9615 (EPEC)
Pathway
eok00670  One carbon pool by folate
eok00790  Folate biosynthesis
eok01100  Metabolic pathways
eok01240  Biosynthesis of cofactors
eok04981  Folate transport and metabolism
Module
eok_M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:eok00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    G2583_0050 (folA)
   00670 One carbon pool by folate
    G2583_0050 (folA)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    G2583_0050 (folA)
Enzymes [BR:eok01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     G2583_0050 (folA)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: ADD54706
LinkDB
Position
54103..54693
AA seq 196 aa
MDSPAEYKIFLNIILAPVDDGLRFTYSGDNFFYREISMISLIAALAVDRVIGMENAMPWN
LPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIA
ACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDA
DAQNSHSYCFEILERR
NT seq 591 nt   +upstreamnt  +downstreamnt
gtggactcgccagcagaatataaaattttcctcaacatcatcctcgcaccagtcgacgac
ggtttacgctttacgtatagtggcgacaattttttttatcgggaaatctcaatgatcagt
ctgattgcggcgttagcggtagatcgcgttatcggcatggaaaacgccatgccgtggaac
ctgcctgccgatctcgcctggtttaaacgcaacaccttaaataaacccgtaattatgggc
cgccatacctgggaatccatcggtcgtccgttgccaggacgcaaaaatattatcctcagc
agtcaaccgggtacggacgatcgcgtaacgtgggtgaagtcggtggatgaagccatcgcg
gcgtgtggtgacgtaccagaaatcatggtgattggcggcggtcgcgtttatgagcagttc
ctgccgaaagcgcaaaaactgtacctgacgcatatcgacgcagaagtggaaggcgacacc
cattttccggattacgagccggatgactgggaatcggtattcagcgaattccacgacgct
gatgcgcagaactctcacagctattgttttgagattctggagcggcggtaa

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