Equus przewalskii (Przewalski's horse): 103540259 Help Entry 103540259         CDS       T04644                                  Symbol INSR Name (RefSeq) insulin receptor isoform X1   KO K04527   insulin receptor [EC:2.7.10.1] Organism epz  Equus przewalskii (Przewalski's horse) Pathway epz04010   MAPK signaling pathway epz04014   Ras signaling pathway epz04015   Rap1 signaling pathway epz04022   cGMP-PKG signaling pathway epz04066   HIF-1 signaling pathway epz04068   FoxO signaling pathway epz04072   Phospholipase D signaling pathway epz04081   Hormone signaling epz04150   mTOR signaling pathway epz04151   PI3K-Akt signaling pathway epz04152   AMPK signaling pathway epz04211   Longevity regulating pathway epz04213   Longevity regulating pathway - multiple species epz04520   Adherens junction epz04910   Insulin signaling pathway epz04913   Ovarian steroidogenesis epz04923   Regulation of lipolysis in adipocytes epz04930   Type II diabetes mellitus epz04931   Insulin resistance epz04932   Non-alcoholic fatty liver disease epz04960   Aldosterone-regulated sodium reabsorption epz05010   Alzheimer disease epz05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:epz00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103540259 (INSR)    04014 Ras signaling pathway     103540259 (INSR)    04015 Rap1 signaling pathway     103540259 (INSR)    04066 HIF-1 signaling pathway     103540259 (INSR)    04068 FoxO signaling pathway     103540259 (INSR)    04072 Phospholipase D signaling pathway     103540259 (INSR)    04022 cGMP-PKG signaling pathway     103540259 (INSR)    04151 PI3K-Akt signaling pathway     103540259 (INSR)    04152 AMPK signaling pathway     103540259 (INSR)    04150 mTOR signaling pathway     103540259 (INSR)   09133 Signaling molecules and interaction    04081 Hormone signaling     103540259 (INSR)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     103540259 (INSR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     103540259 (INSR)    04923 Regulation of lipolysis in adipocytes     103540259 (INSR)    04913 Ovarian steroidogenesis     103540259 (INSR)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     103540259 (INSR)   09149 Aging    04211 Longevity regulating pathway     103540259 (INSR)    04213 Longevity regulating pathway - multiple species     103540259 (INSR)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     103540259 (INSR)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     103540259 (INSR)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     103540259 (INSR)    04932 Non-alcoholic fatty liver disease     103540259 (INSR)    04931 Insulin resistance     103540259 (INSR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:epz01001]     103540259 (INSR)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:epz04090]     103540259 (INSR) Enzymes [BR:epz01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      103540259 (INSR) Protein kinases [BR:epz01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    103540259 (INSR) CD molecules [BR:epz04090]  Proteins   103540259 (INSR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Ig_DSCAM-DSCAML_C Kinase-like DUF4476 Motif Other DBs NCBI-GeneID:  103540259 NCBI-ProteinID:  XP_070478881 LinkDB All DBs Position 6:complement(5087119..5212553) Genome browser AA seq 1382 aa AA seqDB search MGAGGRRGAAAAPLLVAVAALLVGAAGHLYPGEVCPGMDIRNNLTRLHELANCSVIEGHL QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL VIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE ECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTADGLCCHSECL GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHNKCKNSRRQG CHQYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGC TVINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE RNDIALKTNGDQASCENELLTFSHIRTSSDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ NVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFS DERRTYGAKSDIIYVQTNATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWE RQEEDSELYELDYCLKGLKLPSRTWSPPFESEGSQKHNQSEYEESAGECCSCPKTDSQIL KELEESSFRKTFEDYLHNVVFVPRKSSSGPGAEDTRPSRKRRALADVGNVTVAVPTVPGF PNTSSTSTPTSSEERRPFEKVVNKESLVISGLRHFTGYRIELQACNQDSPEERCSVAAYV SARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCV SRRHFALERGCRLRGLPPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIG PLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPR EKITLLRELGQGSFGMVYEGNARDIVKGEAETRVAVKTVNESASLRERIEFLNEASVMKG FTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMVQMA AEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPV RWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDN CPERVTDLMRMCWQFNPKMRPTFLEIVDLLKDDLHPSFPEVSFFHSEENKAPESEELEME FEDMENVPLDRSSHSQREEAGGRDAGSSLGLKRNYEEHIPYTHMNGGKKNGRILTLPRSN PS NT seq 4149 nt NT seq  +upstreamnt  +downstreamnt atgggcgcagggggccggcggggggcggcggccgcgccgctcctggtggccgtggcggcg ctgctggtgggcgccgcgggccacctgtaccccggagaggtgtgccctggcatggatatc cggaacaacctcacgaggctgcacgaactggccaactgctccgtcattgaaggacacttg cagattctgttgatgtttaaaacgaggcctgaggatttccgagacctcagtttccccaaa ctcatcatgatcactgattacttgctgctcttccgggtgtacgggctggagagcctgaag gacctgttccccaacctcacggtcatccggggctctcgtctcttcttcaactacgcgctg gtcatcttcgagatggttcacctgaaggagcttggcctctacaacctgatgaacatcacc cgcggctccgtccgcatagagaagaacaacgagctgtgctacctggccaccattgactgg tcacgcattctggactcggtggaagataattacattgtgctgaacaaggacgacaatgag gagtgcggggacatttgtccaggcaccgccaagggcaagaccaactgccccgccactgtc atcaacggacagtttgttgagcggtgctggacgcacagccattgccagaaagtttgcccg accatctgtaagtcacacggctgcaccgcggacggcctctgctgccacagcgagtgttta ggcaactgctctgagcccgacgaccccaccaagtgcgtggcctgccgcaacttctacctg gacggcaggtgtgtggagacctgcccgcccccgtactatcacttccaagactggcgctgt gtcaacttcagcttctgccaggacctgcacaacaaatgcaagaactcccgaaggcagggc tgccatcagtacgtcattcacaataacaagtgcatccctgagtgtccctctgggtacacg atgaattccagcaacttgatgtgtaccccgtgcctgggtccctgtcccaaggtgtgccac ctcctggaaggcgagaagaccatcgactcggtgacgtccgcccaggagctccgaggctgc acggtcatcaacgggagcctgatcatcaacatccgagggggcaacaacctggcagctgag ctagaggccaaccttggactcattgaagaaatttcagggtatctgaaaatccgccggtcc tacgctctcgtgtcgctttccttcttccggaagttacgcctaattcggggagagaccttg gaaatcgggaactactcattctacgccttggacaaccagaacctgaggcagctatgggac tggagcaagcacaacctcaccatcactcaggggaaactcttcttccactataatcccaaa ctctgcttgtcggaaattcacaagatggaggaagtttcaggaaccaaagggcgccaggag aggaacgacatcgccctgaagaccaacggggaccaggcgtcctgtgaaaatgagttactt acattttctcacattcggacatcttctgacaagatcttgctgaaatgggagccatattgg ccccccgacttccgagacctcttgggcttcatgctcttctataaagaggccccttatcag aacgtgacggagttcgatgggcaggatgcctgtggctccaacagctggacggtagtggac attgacccacctctgaggtccaacgaccccaagtcacagaaccaccccgggtggctgatg cgaggtctcaaaccctggacccagtatgccatctttgtcaagaccttggtcaccttttct gatgaacgccggacatacggggccaagagcgacatcatctatgtccagacaaatgccacg aacccgtctgtccccctggatcccatctccgtttctaattcctcatcccagattattctg aagtggaagcccccctctgaccccaatgggaacatcacacactacctggttttctgggag aggcaggaggaagacagcgagctgtacgagttggattattgcctcaaaggcttgaagctg ccctccaggacctggtctccaccgtttgagtctgaggggtcccagaagcacaatcagagt gagtacgaggagtctgccggcgaatgctgctcctgcccgaagaccgactcccagatcctg aaggagctggaggagtcctcgttcaggaagacgttcgaggactatctgcacaatgtggtt tttgtccccagaaaatcctcttcaggccctggtgccgaggacactagaccgtctcggaaa cgcagggcgcttgctgatgtcgggaatgtgacggtggccgtgcccacggttccgggtttc cctaatacctcctccaccagcacgcccacgagctcagaggagcgcagacccttcgagaaa gtggtgaacaaggagtcgctggtcatctccggcctgcgccattttaccgggtatcgcatc gagcttcaggcttgcaaccaagattcccccgaagagaggtgcagtgtggccgcctatgtc agtgccaggaccatgcctgaagccaaggcggacgacatcgttggccccgtgactcacgaa atcttcgagaacaatgtcgttcacttgatgtggcaggagcccaaagaacccaacggtctg atcgtgctgtacgaagtgagttatcggcgatacggcgatgaggagctgcatctctgtgtg tctcgcagacattttgccctggagcggggctgccggctgcgtgggctgccgccagggaac tacagtgtgcgagtgcgggccacctccctggcaggcaatggctcctggaccgaagccact tatttctacgtgacagactatttagacgtcccatcaaatattgcaaaaatcatcatcggc cccctcatctttgtctttctcttcagtgtggtcattggaagcatttacctcttcttgaga aagaggcagccggatgggcccctgggaccgctgtacgcttcctcaaaccctgagtacctc agcgccagtgatgtgtttccctgctctgtgtacgtgccggacgagtgggaggtgcctcgg gagaagatcaccctcctgcgggagctggggcagggctccttcggcatggtgtatgaaggc aacgccagggacatcgtcaagggcgaggcggagacccgcgtggcggtgaagacagtcaac gagtctgccagtctgcgagagaggatcgagtttctcaacgaggcctcagtcatgaagggc ttcacctgccatcacgtggtccgcctcctgggggtggtatcgaaaggccagccaacgctg gtggtgatggagttgatggctcatggagacctgaagagctacctccgttccctgcggccg gaggctgagaataaccctggccgccctccccctaccctgcaagagatggttcagatggcg gcggagatcgccgacgggatggcgtacctgaacgccaagaagtttgtgcaccgggacctg gcagctcgaaactgcatggtcgcccacgattttaccgtcaaaatcggagactttggaatg accagagacatctacgaaacggattactaccggaaaggaggcaaggggctgctccccgtg aggtggatggctcctgaatccctgaaggacggggtctttactacttcttctgacatgtgg tcctttggcgtggtcctttgggaaatcaccagcttggcagaacagccttaccaaggcctg tctaatgagcaggtgttgaaatttgtcatggatggagggtatctggatcaacccgacaat tgtcccgagagagtcaccgacctgatgcgtatgtgctggcagttcaaccccaagatgcgg ccgaccttcctggagattgtcgacctgctcaaggatgacctgcaccccagctttccagaa gtttccttcttccacagcgaggagaacaaggcccccgagagcgaggagctggagatggag tttgaggacatggagaacgtccccctggatcggtcctcacattcccagagggaggaggcc gggggccgggatgcagggtcctcgctgggtctaaagcggaactatgaggaacacatcccg tacactcacatgaacgggggcaagaaaaatgggcggattctgactctgccgaggtcaaat ccttcctaa

DBGET integrated database retrieval system