Equus przewalskii (Przewalski's horse): 103542314
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Entry
103542314 CDS
T04644
Symbol
JAK3
Name
(RefSeq) tyrosine-protein kinase JAK3 isoform X1
KO
K11218
Janus kinase 3 [EC:
2.7.10.2
]
Organism
epz
Equus przewalskii (Przewalski's horse)
Pathway
epz04062
Chemokine signaling pathway
epz04151
PI3K-Akt signaling pathway
epz04217
Necroptosis
epz04550
Signaling pathways regulating pluripotency of stem cells
epz04630
JAK-STAT signaling pathway
epz04658
Th1 and Th2 cell differentiation
epz04659
Th17 cell differentiation
epz05161
Hepatitis B
epz05162
Measles
epz05166
Human T-cell leukemia virus 1 infection
epz05169
Epstein-Barr virus infection
epz05200
Pathways in cancer
epz05203
Viral carcinogenesis
epz05223
Non-small cell lung cancer
epz05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
epz00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
103542314 (JAK3)
04151 PI3K-Akt signaling pathway
103542314 (JAK3)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
103542314 (JAK3)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
103542314 (JAK3)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
103542314 (JAK3)
04659 Th17 cell differentiation
103542314 (JAK3)
04062 Chemokine signaling pathway
103542314 (JAK3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103542314 (JAK3)
05203 Viral carcinogenesis
103542314 (JAK3)
09162 Cancer: specific types
05223 Non-small cell lung cancer
103542314 (JAK3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
103542314 (JAK3)
05161 Hepatitis B
103542314 (JAK3)
05162 Measles
103542314 (JAK3)
05169 Epstein-Barr virus infection
103542314 (JAK3)
09163 Immune disease
05340 Primary immunodeficiency
103542314 (JAK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
epz01001
]
103542314 (JAK3)
Enzymes [BR:
epz01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
103542314 (JAK3)
Protein kinases [BR:
epz01001
]
Non-receptor tyrosine kinases
JAK family [OT]
103542314 (JAK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
SH2_1
FERM_F1
Jak1_Phl
Kinase-like
ABC1
LRR_RI_capping
SH2
FERM_M
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
103542314
NCBI-ProteinID:
XP_070442672
LinkDB
All DBs
Position
20:complement(2645353..2660398)
Genome browser
AA seq
1104 aa
AA seq
DB search
MEPPSEETPLIAQRSCSLSSSEAGALHVLLPPRGPGPPQRLSFSFGDHSAEELCVRAAKA
SAILPVYHSLFALATEDLSCWFPPSHIFSVEDAGTQVLVYRLRFYFPNWFGLEKCHRFGL
RKDLASAILDLPVLEHLFAQHRNDLLSGRLPVGLGLKEQGECLSLAVLDLARMAREQAQR
PEELLKTVSYKACLPPGLRDLIQGLSFVTRKRIRRTVRRALRRVVACQADRHSLMAKYIM
DLERLDPAGAAETFLVGLPGGAGGQDAPGLLRVAGGSGIAWSPGGDEALQPFCDFPEIVD
ISIKQAPRVGPAGEHRLVTVTRTDNQILEAEFPGLPAALSFVALVDGYFRLTADSRHFFC
KEVAPPRLLEEVAEQCHGPITLDFAVNKLKTGGSLPGSYVLRRSPQDFDSFLLTVCVQTP
LGPDYKGCLIRCDPTGTFSLAGLGRPHSSLRELLAACWDGGLHVDGVALNLTSCCTPKPK
EKSNLIVVRRGCTPPTPSLVQPPSRCQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGHR
HEAVDGEARETEVLLKVMDAKHKNCMESFLEAASLMSQVSYQHLVFLHGVCMAGDSIMVQ
EFVRLGALDTYLRKCGHLVPASWKLQVIKQLAYALNYLEDKGLPHGNVSARKVLLAREGA
DGSPPFIKLSDPGVSPAVLSLEMLTDRIPWVAPECLQEAHTLGLEADKWGFGATVWEVFS
GVTMPISMLDPAKKLQFYQERQQLPAPKWTELALLIQQCMAYERGLRPSFRGIIRDLNSL
ITSDYELLSDPTPGALAPRDGLWNGAQLYACQDPTIYEERHLKYISQLGKGNFGSVELCR
YDPLGDNTGALVAVKQLQHSGPEQQRDFQREVQILRALHSDFIVKYRGVSYGPGRQSLRL
VMEYLPSGCLRDFLQRHRARLHAGRLLLYASQICKGMEYLGSQRCVHRDLAARNILVESE
THVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYEL
FTYSDKSCSPSAEFLRMMGCERDAPALCRLLELLAEGQRLPAPPACPAEVHELMKLCWAP
SPQDRPPFSALGPQLEALWSGSRG
NT seq
3315 nt
NT seq
+upstream
nt +downstream
nt
atggagccaccaagcgaggagacgcccctgatcgctcagcgctcctgcagcctctcgtct
tcagaggccggtgctctgcatgtgctgctgccccctcggggccctgggcccccgcagcgc
ctatccttctcctttggggaccattcagctgaagagctgtgtgttcgggctgctaaggcc
agtgccatcctgcccgtgtaccactccctctttgctctggccaccgaggacctgtcctgc
tggttccccccaagccacatcttctctgtggaggatgcgggcacccaggtccttgtctac
agactccgcttttactttcccaactggtttgggctagagaagtgccaccgcttcgggcta
cgaaaggacttggccagcgccatccttgacctgccagtcctggagcacctcttcgcgcag
caccgcaacgatctgctgagcggccgcctccccgtgggccttggcctcaaggaacagggc
gagtgtctcagcctggccgtgctggacctggcccggatggcccgtgagcaggcgcagcgg
cctgaagagctgctgaagaccgtcagctacaaggcctgcctgccccccggcctgcgcgat
ctgatccagggcctgagcttcgtgactcggaagcgtatccggaggaccgtgcgccgggcc
ctgcgccgcgtggtcgcctgccaggctgacaggcactcgctcatggccaagtacatcatg
gacctggagcggctggacccggccggggccgccgagaccttcctcgtgggcctccccggg
ggtgctggtggtcaggacgcgcccgggctgctccgcgtggctggtggcagcggcattgcc
tggagcccgggcggagacgaggccctccagcccttctgcgactttccagaaatcgtggac
atcagcatcaagcaggccccgcgcgttggcccggccggggagcaccgtctggtcaccgtc
accaggacagacaaccagatcctggaggccgagttcccggggctgcccgcggccttgtcc
ttcgtggcgctcgtggacggctacttccggctgacagccgactcccggcacttcttctgc
aaggaggtggcgcccccgcggctgctcgaggaggtggccgagcagtgccacggccccatc
accctggattttgcagttaacaagctcaagactgggggctcgcttccgggctcctacgtt
ctccgccgcagtccccaggattttgacagcttcctcctcactgtctgtgtccagaccccc
ctgggccctgattacaagggctgcctcatccggtgcgaccccacgggaaccttctccctg
gctggcctcgggcgtccccatagcagtcttcgagaactcctggcagcctgctgggatggt
ggcctgcatgtggacggagtcgcgctgaacctcacctcctgctgcacccctaaacccaaa
gaaaagtccaatctgattgtggtccggagagggtgcaccccacccacgccatccctggtt
caacccccatcccgctgccagctgagtcagatgacgtttcacaagatcccggctgacagc
ctggagtggcacgagaacctgggtcatgggtccttcaccaagatttaccggggtcatcgc
cacgaggccgtggacggggaggcccgggagacagaggtgctgctgaaagtgatggatgcc
aagcacaagaactgcatggagtcgttcctggaagcagcgagcttgatgagccaagtgtca
taccagcacctcgtgttcctgcatggcgtgtgcatggctggagacagcatcatggtgcag
gaatttgtccgcctgggggcgctggacacatatctgcgcaagtgtggccatctggtgccg
gccagctggaagctgcaggtgatcaaacagctggcctatgccctcaactatctggaagac
aaaggccttccccatggcaatgtctcagcccggaaggtgctcctggctcgggagggggct
gacgggagcccgcctttcatcaagctgagtgaccctggggtcagccctgctgtgctaagc
ctggagatgctcaccgacaggatcccctgggtggcccctgagtgtctccaggaggcacac
acacttggcttggaggctgacaagtggggcttcggtgccacagtctgggaggtgttcagc
ggtgtcacgatgcccatcagcatgctggaccccgccaagaagctccagttttaccaggaa
cggcagcagctgccagcccccaagtggacggagctggcgctgctgatccagcagtgcatg
gcctacgagcggggcctcagaccctccttccgcggcatcatccgtgacctgaacagcctc
atcacctcagattatgagctcctctcggaccccactcctggtgccctggcgccccgtgac
gggctgtggaatggcgcccagctctatgcctgccaggaccccaccatctatgaggagagg
cacctcaagtacatctcgcagctgggcaagggcaacttcggcagcgtggagctgtgccgc
tatgacccgctgggtgacaacacaggcgccctggtggccgtgaagcagctgcagcacagc
gggccagagcagcagagggacttccagcgggaggtccagatcctgcgagccctgcacagc
gacttcatcgtcaagtaccgcggcgtcagctacggcccaggccgccagagcctgcggctg
gtcatggagtacctgcccagcggctgcctgcgcgacttcctgcagcggcaccgcgcgcgc
ctccacgccggccgtctgctcctctacgcctcgcagatctgcaagggcatggagtacctg
ggctcccaacgctgcgtgcaccgcgacctggcagctcggaacatcctggtggagagcgag
acgcacgtcaagatcgccgacttcggcctcgccaagttgctgccgctcgacaaagactac
tacgtggtccgcgagcccggccagagccccattttctggtacgccccagagtcgctctcc
gacaacatcttctcgcgccagtcggacgtctggagcttcggggtggtcctgtacgagctc
ttcacgtacagcgacaagagctgcagcccctcggccgagttcctgcgcatgatgggctgt
gagcgagacgccccggccctgtgccgcctcctggagctgctggccgagggccagaggctg
cccgcgcctcctgcctgccccgccgaggttcatgagctcatgaagctgtgctgggccccc
agcccacaagaccggccgccgttcagtgccctgggcccccagctggaggcgctgtggagt
gggagccgggggtag
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