Equus przewalskii (Przewalski's horse): 103550430 Help Entry 103550430         CDS       T04644                                  Symbol ADCY1 Name (RefSeq) adenylate cyclase type 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism epz  Equus przewalskii (Przewalski's horse) Pathway epz00230   Purine metabolism epz01100   Metabolic pathways epz01522   Endocrine resistance epz04015   Rap1 signaling pathway epz04020   Calcium signaling pathway epz04022   cGMP-PKG signaling pathway epz04024   cAMP signaling pathway epz04062   Chemokine signaling pathway epz04072   Phospholipase D signaling pathway epz04081   Hormone signaling epz04082   Neuroactive ligand signaling epz04114   Oocyte meiosis epz04211   Longevity regulating pathway epz04213   Longevity regulating pathway - multiple species epz04261   Adrenergic signaling in cardiomyocytes epz04270   Vascular smooth muscle contraction epz04371   Apelin signaling pathway epz04540   Gap junction epz04611   Platelet activation epz04713   Circadian entrainment epz04714   Thermogenesis epz04720   Long-term potentiation epz04723   Retrograde endocannabinoid signaling epz04724   Glutamatergic synapse epz04725   Cholinergic synapse epz04727   GABAergic synapse epz04750   Inflammatory mediator regulation of TRP channels epz04911   Insulin secretion epz04912   GnRH signaling pathway epz04913   Ovarian steroidogenesis epz04914   Progesterone-mediated oocyte maturation epz04915   Estrogen signaling pathway epz04916   Melanogenesis epz04918   Thyroid hormone synthesis epz04921   Oxytocin signaling pathway epz04923   Regulation of lipolysis in adipocytes epz04925   Aldosterone synthesis and secretion epz04926   Relaxin signaling pathway epz04927   Cortisol synthesis and secretion epz04928   Parathyroid hormone synthesis, secretion and action epz04934   Cushing syndrome epz04935   Growth hormone synthesis, secretion and action epz04970   Salivary secretion epz04971   Gastric acid secretion epz04972   Pancreatic secretion epz04976   Bile secretion epz05032   Morphine addiction epz05142   Chagas disease epz05146   Amoebiasis epz05163   Human cytomegalovirus infection epz05166   Human T-cell leukemia virus 1 infection epz05200   Pathways in cancer epz05207   Chemical carcinogenesis - receptor activation epz05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:epz00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     103550430 (ADCY1)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     103550430 (ADCY1)    04371 Apelin signaling pathway     103550430 (ADCY1)    04020 Calcium signaling pathway     103550430 (ADCY1)    04072 Phospholipase D signaling pathway     103550430 (ADCY1)    04024 cAMP signaling pathway     103550430 (ADCY1)    04022 cGMP-PKG signaling pathway     103550430 (ADCY1)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     103550430 (ADCY1)    04081 Hormone signaling     103550430 (ADCY1)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     103550430 (ADCY1)   09144 Cellular community - eukaryotes    04540 Gap junction     103550430 (ADCY1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     103550430 (ADCY1)    04062 Chemokine signaling pathway     103550430 (ADCY1)   09152 Endocrine system    04911 Insulin secretion     103550430 (ADCY1)    04923 Regulation of lipolysis in adipocytes     103550430 (ADCY1)    04912 GnRH signaling pathway     103550430 (ADCY1)    04913 Ovarian steroidogenesis     103550430 (ADCY1)    04915 Estrogen signaling pathway     103550430 (ADCY1)    04914 Progesterone-mediated oocyte maturation     103550430 (ADCY1)    04921 Oxytocin signaling pathway     103550430 (ADCY1)    04926 Relaxin signaling pathway     103550430 (ADCY1)    04935 Growth hormone synthesis, secretion and action     103550430 (ADCY1)    04918 Thyroid hormone synthesis     103550430 (ADCY1)    04928 Parathyroid hormone synthesis, secretion and action     103550430 (ADCY1)    04916 Melanogenesis     103550430 (ADCY1)    04925 Aldosterone synthesis and secretion     103550430 (ADCY1)    04927 Cortisol synthesis and secretion     103550430 (ADCY1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     103550430 (ADCY1)    04270 Vascular smooth muscle contraction     103550430 (ADCY1)   09154 Digestive system    04970 Salivary secretion     103550430 (ADCY1)    04971 Gastric acid secretion     103550430 (ADCY1)    04972 Pancreatic secretion     103550430 (ADCY1)    04976 Bile secretion     103550430 (ADCY1)   09156 Nervous system    04724 Glutamatergic synapse     103550430 (ADCY1)    04727 GABAergic synapse     103550430 (ADCY1)    04725 Cholinergic synapse     103550430 (ADCY1)    04720 Long-term potentiation     103550430 (ADCY1)    04723 Retrograde endocannabinoid signaling     103550430 (ADCY1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     103550430 (ADCY1)   09149 Aging    04211 Longevity regulating pathway     103550430 (ADCY1)    04213 Longevity regulating pathway - multiple species     103550430 (ADCY1)   09159 Environmental adaptation    04713 Circadian entrainment     103550430 (ADCY1)    04714 Thermogenesis     103550430 (ADCY1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103550430 (ADCY1)    05207 Chemical carcinogenesis - receptor activation     103550430 (ADCY1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     103550430 (ADCY1)    05163 Human cytomegalovirus infection     103550430 (ADCY1)   09174 Infectious disease: parasitic    05146 Amoebiasis     103550430 (ADCY1)    05142 Chagas disease     103550430 (ADCY1)   09165 Substance dependence    05032 Morphine addiction     103550430 (ADCY1)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     103550430 (ADCY1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     103550430 (ADCY1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     103550430 (ADCY1) Enzymes [BR:epz01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      103550430 (ADCY1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom DUF7246 Motif Other DBs NCBI-GeneID:  103550430 NCBI-ProteinID:  XP_008517530 LinkDB All DBs Position 4:16025630..16176329 Genome browser AA seq 1141 aa AA seqDB search MAGAPRGRGGGGGGGGAGEGGGGAGEPGGAERAARPGGRRGLRACNEEFACPELEALFRG YTLRLEQAATLKALAVLSLLAGALALAELLGAPGPAPGLAKGSHPVHCVLFLALLVVTNV RSLQVPQLQQVGQLALLFSLTFALLCCPFALGGPAGAHAGAAAVPATADQGVWQLLLVTF VSYALLPVRSLLAIGFGLLVAASHLLVTATLVPAKRPRLWRTLGANALLFLSVNMFGVFV RILAERSQRKSFLQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIF HKIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILG DCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGL RKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNSFLKAHNI ETFFIVPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCE DDDKRRALRTASEKLRNRSSFSANVVYTTPGTRVNRYISRLLEARQPELEMADLNFFTLK YKQAERERKYHQLQDEYFTSAVVLALALAALFSLVYLLIIPQNLAVLLLLVFSICFLVAC VLYLHITRVQCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWAWSSSPNGSLVFLS SGGRSPVLPAPPCESAPHALLCGLVGTLPLAIFLRVSSLPKMILLSVLTASYILVLELSG YTKAVGGGTVSGRSFEPIVAILLFSCTLALHARQVDVKLRLDYLWAVQAEEERDDMERVK LDNKRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMG VECLRLLNEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTAGAKAKKCISSHLGT LADFAIEMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMD STGVQGRIQVTEEVHRLLRRGAYRFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQSRSLNS ERKMYPYGRAGLQTRLATGHPPVPAVAGLPVTAGLGALQGSGIAPGPPGPPLPPGAAGKE A NT seq 3426 nt NT seq  +upstreamnt  +downstreamnt atggcgggggcgccgcgcggccgaggcggcggcggaggcggagggggcgcgggcgaaggc ggagggggcgcgggcgagcccgggggcgccgagcgggcggcccggccgggcggccggcgc gggctgcgagcgtgcaacgaggagttcgcgtgccccgagctggaggcgctgttccgcggc tacacgctgcggctggagcaggcggccacgctgaaggcgctggcggtgctcagcctgctg gcaggcgcgctggcgctggccgagctgctgggcgcgccggggcccgcgcccggcctggcc aagggctcgcaccccgtgcactgcgtgctcttcctggcgctgctcgtggtcaccaacgtc cgctcgctgcaggtgccccagctgcagcaggtcggccagctcgcgctgctcttcagcctc accttcgcgctgctctgctgcccctttgcgctcggcggccccgccggggcccacgctggg gcggctgcggtgccggcgactgccgaccagggtgtttggcagctcctcttggtcaccttc gtgtcctatgccctgcttcctgtgcgcagcctgctggccatcggctttgggctcctggtg gccgcctcgcacttgctggtcacggccaccttggtccccgccaagcgcccacgtctctgg aggacgctcggggcgaatgccctcctcttcctcagcgtgaacatgttcggcgtctttgtg aggatcctggccgagcgctcccagaggaagtccttcctgcaggcccgaaactgcatcgag gaccggctgcgactggaggacgagaatgagaagcaggagcggctgctcatgagtctcttg ccccggaacgtcgccatggagatgaaggaggacttcctgaagccccccgagaggattttc cacaagatttacatccagcggcatgacaacgtgagcatcctcttcgcagacatcgtgggc ttcacgggcttggcgtctcagtgcacggcccaggagctggtgaaactcctcaacgagctc ttcggcaagtttgatgaattggccacggagaaccactgccgccgcatcaagatcctcgga gactgttactactgcgtgtctggcctcacccagcccaagactgaccacgcccattgctgt gtggagatgggcctggacatgatcgacaccatcacgtccgtggccgaggccaccgaggtg gacctgaacatgcgtgtggggctgcacaccggcagggtcctctgcggggtcctgggcctg cgcaagtggcagtatgatgtgtggtccaacgacgtgaccttggccaatgtcatggaggcc gccggcctgccggggaaggttcatatcacgaagaccaccctggcgtgcttgaatggcgac tatgaggtggaaccaggtcacggacacgagaggaacagttttctgaaagctcacaatatc gagaccttttttattgtgccatcgcatcggcgaaagatatttccggggctgattctctca gacataaagccggccaagaggatgaagttcaagaccgtgtgctacctgctggtgcagctc atgcactgccggaagatgttcaaggcggagatccccttctccaacgtcatgacctgcgag gatgatgacaagcggagggctttgagaacagcctcggaaaaactcagaaaccgctcgtct ttctctgcgaacgttgtgtacaccaccccgggcacgcgcgtcaataggtacatcagccgc ctcctagaagcccgccagccagaactggagatggcagacctgaacttcttcaccctgaag tacaagcaagctgagcgagagcgaaagtaccaccagctccaggacgagtacttcaccagc gccgtcgtgctcgccctcgccctggccgccttattcagcctcgtctaccttctgatcatc ccgcagaacttggctgtcctgctcctgctggtgttctccatctgcttcctggtggcctgt gtcctgtacctgcacatcacccgggtccagtgttttccagggtgcctgacgatccagatt cgtaccgtcctgtgtattttcatagtggtcttaatctattctgtggcccaaggatgtgtg gtgggctgtctgccctgggcctggagctccagtcccaacgggtctctggtgttcctgtcg tccggcggccggagcccagtgctgcctgccccgccctgcgagtctgcaccccatgccctg ctctgtggcctggtgggcaccctcccgctggccatattcctgcgggtctcttccttgccc aaaatgatcctgctctccgtgctcacggcgtcctacatcctggtcctggagctcagcggg tacaccaaggccgtggggggcggcactgtctctgggcgcagcttcgagccgattgtggcc atcctgctgttctcgtgcacgctggccctgcacgcccggcaggtggacgtcaagctgcgg ctggactacctctgggctgtgcaggcagaggaggagcgagacgacatggagcgggtgaag ctggacaataagaggattctcttcaatctcctgccggcccacgtcgcccagcatttcctc atgtccaacccccggaacatggacctctactaccagtcgtactcgcaggtgggcgtcatg ttcgcctccatccccaacttcaacgacttctacatcgagctggatggcaacaacatgggg gtggagtgcctgcgcctcctgaacgagatcattgccgacttcgacgagctcatggacaaa gacttttacaaggacctggagaagatcaagaccattgggagcacttatatggccgcggtg ggattggcgcccacggctggggccaaggctaagaagtgtatctcctcccacctcggcacg ctggcggatttcgccatcgagatgttcgacgtcctggatgagatcaactaccagtcttac aatgacttcgtgctccgtgtcggcatcaacgttggccccgtggtggctggggtgattggg gctcgcaggccgcagtatgacatctggggaaacactgtcaacgtggccagtcggatggac agcaccggggtccagggcagaatccaggtgacggaggaggtgcaccggctgctgcggcgg ggtgcgtaccgtttcgtgtgccgaggcaaagtcagtgtcaagggcaagggcgagatgcta acatacttcctggaaggcaggaccgacggaaatggctcccaatccaggtccctgaactcg gagcggaaaatgtatccttacggcagagctggcctccagaccagactggccacgggccac ccccctgtgcccgccgtggctggcctcccggtcacagctgggctgggggctctgcagggc tcggggatcgcccctgggcctcccggcccacccctgccccctggagcagctggaaaggag gcttag

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