Equus przewalskii (Przewalski's horse): 103553776
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Entry
103553776 CDS
T04644
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
epz
Equus przewalskii (Przewalski's horse)
Pathway
epz04120
Ubiquitin mediated proteolysis
epz04144
Endocytosis
epz04330
Notch signaling pathway
epz04668
TNF signaling pathway
epz04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
epz00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
103553776 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
103553776 (ITCH)
04668 TNF signaling pathway
103553776 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
103553776 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
103553776 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
epz04131
]
103553776 (ITCH)
04121 Ubiquitin system [BR:
epz04121
]
103553776 (ITCH)
Enzymes [BR:
epz01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
103553776 (ITCH)
Membrane trafficking [BR:
epz04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
103553776 (ITCH)
Ubiquitin system [BR:
epz04121
]
Ubiquitin ligases (E3)
HECT type E3
103553776 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
103553776
NCBI-ProteinID:
XP_070444212
LinkDB
All DBs
Position
21:25194845..25303935
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AA seq
891 aa
AA seq
DB search
MKHWAACSGARELNNSAAGPAPVCRPIGGMSDSGSQLGSMGSLTMKSQLQITVISAKLKE
NKKNWFGPSPYVEVTVDGQSKKTEKCNNTSSPKWKQPLTVIVTPVSKLHFRVWSHQTLKS
DVLLGTAALDIYETLKSNNMKLEEVVVTLQLVGDKEPTETIGDLSVCLDGLQLESEVVTN
GETTCSESASQNDDSSRPKDETRASTNGSDDPEDVGSVENRRVNGNNSPSLSNGGFKPSR
PPRPSRPPPPTPRRPASVNGSPSATSESDGSSTGSLPLTNTNSNTSEGATSGLIIPLTIS
GGSGPRPLNPVPQAPLPPGWEQRVDQHGRVYYVDHIEKRTTWDRPEPLPPGWERRVDNMG
RIYYVDHFTRTTTWQRPTLESVRNYEQWQLQRSQLQGAMQQFNQRFIYGNQDLFATSQNK
EFDPLGPLPPGWEKRTDSNGRVYFVNHNTRITQWEDPRSQGQLNEKPLPEGWEMRFTVDG
IPYFVDHNRRTTTYIDPRTGKSALDNGPQIAYVRDFKAKVQYFRFWCQQLTMPQHIKITV
TRKTLFEDSFQQIMSFSPQDLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLF
EYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPV
GLKDLESIDPEFYNSLIWVKENNIEECGLEMYFSVDKEILGEIKSHDLKPNGGNILVTEE
NKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLND
WQRHAIYRHYTRTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQ
KFCIEKVGKENWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE
NT seq
2676 nt
NT seq
+upstream
nt +downstream
nt
atgaaacactgggccgcctgcagtggagcccgcgaacttaacaactcggctgcagggcca
gccccggtttgccgtcctattggtggtatgtctgacagtggatcacagcttggttcaatg
ggtagcctgaccatgaaatcacaacttcagatcactgtcatttcagcaaaacttaaagaa
aataaaaagaattggtttggaccgagtccttatgtggaagtcacagtagatggacagtca
aagaagacagaaaaatgcaacaatacaagtagtcccaaatggaagcaaccccttacagtt
atcgtcacccctgtgagtaaattacattttcgtgtgtggagtcaccagacgctgaaatct
gacgttttgttgggaactgctgcattagatatctatgaaacattaaagtcaaacaatatg
aaacttgaggaagtagttgtgactttacagcttgtaggtgacaaagagccgacagagaca
ataggagacttgtcagtttgtcttgatgggctgcagttagagtctgaagttgttaccaat
ggtgaaactacgtgttcagaaagtgcttcacagaatgatgatagctccagacccaaggac
gaaacaagagcaagcacaaatggatcagatgaccctgaggacgtagggtctgttgaaaat
aggagggtcaatgggaataattctccatcactctcaaatggcggttttaaaccttctagg
cctccaagaccatcacgaccacctccacctaccccacgtagaccagcatctgtcaatggt
tcaccatctgccacttctgaaagtgatggatctagcacaggctctctgccactaacgaat
acaaattcaaatacatctgaaggagcaacgtctggattaataattcctcttactatatct
ggaggctcaggccctaggccattaaatcctgtacctcaagctcccctaccacctggttgg
gagcagagagtggaccagcatgggcgagtttactatgtagatcatattgaaaaaagaaca
acgtgggatagaccagaacctctacctcctggctgggaacggcgggttgacaacatggga
cgtatttattatgttgaccatttcacaagaacaacaacgtggcagaggccaacattggaa
tccgtccggaactatgaacagtggcagctccaacgtagtcaacttcaaggagcaatgcag
cagtttaatcagagattcatttatgggaatcaagatttgtttgctacatcacaaaataaa
gaatttgatccccttggtcccctgccacctggatgggagaagagaacggacagcaatggt
agagtatattttgtcaaccacaatactcgtattacacaatgggaagatcccagaagtcaa
ggtcaactaaatgaaaagcccttacctgaaggctgggaaatgagattcacagtggatgga
attccatattttgtggaccacaatagaagaacaaccacctatatagatccccgcactgga
aaatctgccctagacaatggaccccagatagcctatgtacgagacttcaaggcaaaggtt
cagtatttccggttctggtgtcagcaactgaccatgccacagcacataaagattacagtg
acaagaaaaacattgtttgaggattcctttcagcagataatgagcttcagtccccaagat
ctgcgaagacgtttgtgggtgatttttccaggagaagaaggtttagattatggaggtgta
gcaagagaatggttctttcttttgtcacatgaggtgttgaacccaatgtattgcctgttt
gaatatgcagggaaggataactactgcttgcagataaacccagcttcttacatcaatcca
gatcacctgaaatattttcgttttattggcaggtttattgccatggctctgttccatggg
aaattcattgacacaggtttttctttgccattctataagcgtatcttgaacaaaccagtt
ggactaaaggatttagaatctattgatccagaattttacaattctctcatctgggttaaa
gaaaacaatattgaggaatgtggtttggaaatgtacttctctgttgataaagaaatttta
ggtgaaatcaagagtcatgatttgaaacccaatggcggcaatattcttgtaacagaagaa
aataaagaggaatatatcagaatggtagctgaatggaggttgtctcgaggtgttgaagaa
cagacacaagctttttttgagggctttaatgaaattcttccccagcagtatttgcaatac
tttgatgcaaaggaattagaggtcctattatgtggaatgcaagagattgatctgaatgac
tggcaaagacatgcaatctaccgtcattacactaggacaagcaagcaaatcatgtggttt
tggcagtttgttaaagaaatcgataatgagaagagaatgagacttctgcagtttgttact
ggaacctgccgattgcccgttggaggatttgctgacctcatggggagcaatggaccacag
aaattctgcattgaaaaagttgggaaagaaaattggttacccagaagtcatacctgtttt
aaccgcctggacctgccaccctacaagagctatgagcaactgaaggaaaagctgttattt
gccattgaagaaactgaaggatttggacaagagtaa
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