KEGG   Equus przewalskii (Przewalski's horse): 103562469
Entry
103562469         CDS       T04644                                 
Symbol
TNF
Name
(RefSeq) tumor necrosis factor isoform X1
  KO
K03156  tumor necrosis factor superfamily, member 2
Organism
epz  Equus przewalskii (Przewalski's horse)
Pathway
epz01523  Antifolate resistance
epz04010  MAPK signaling pathway
epz04060  Cytokine-cytokine receptor interaction
epz04061  Viral protein interaction with cytokine and cytokine receptor
epz04064  NF-kappa B signaling pathway
epz04071  Sphingolipid signaling pathway
epz04150  mTOR signaling pathway
epz04210  Apoptosis
epz04217  Necroptosis
epz04350  TGF-beta signaling pathway
epz04380  Osteoclast differentiation
epz04612  Antigen processing and presentation
epz04620  Toll-like receptor signaling pathway
epz04621  NOD-like receptor signaling pathway
epz04622  RIG-I-like receptor signaling pathway
epz04625  C-type lectin receptor signaling pathway
epz04640  Hematopoietic cell lineage
epz04650  Natural killer cell mediated cytotoxicity
epz04657  IL-17 signaling pathway
epz04660  T cell receptor signaling pathway
epz04664  Fc epsilon RI signaling pathway
epz04668  TNF signaling pathway
epz04920  Adipocytokine signaling pathway
epz04930  Type II diabetes mellitus
epz04931  Insulin resistance
epz04932  Non-alcoholic fatty liver disease
epz04933  AGE-RAGE signaling pathway in diabetic complications
epz04936  Alcoholic liver disease
epz04940  Type I diabetes mellitus
epz05010  Alzheimer disease
epz05014  Amyotrophic lateral sclerosis
epz05020  Prion disease
epz05022  Pathways of neurodegeneration - multiple diseases
epz05132  Salmonella infection
epz05133  Pertussis
epz05134  Legionellosis
epz05135  Yersinia infection
epz05140  Leishmaniasis
epz05142  Chagas disease
epz05143  African trypanosomiasis
epz05144  Malaria
epz05145  Toxoplasmosis
epz05146  Amoebiasis
epz05152  Tuberculosis
epz05160  Hepatitis C
epz05161  Hepatitis B
epz05163  Human cytomegalovirus infection
epz05164  Influenza A
epz05165  Human papillomavirus infection
epz05166  Human T-cell leukemia virus 1 infection
epz05168  Herpes simplex virus 1 infection
epz05169  Epstein-Barr virus infection
epz05170  Human immunodeficiency virus 1 infection
epz05171  Coronavirus disease - COVID-19
epz05205  Proteoglycans in cancer
epz05310  Asthma
epz05321  Inflammatory bowel disease
epz05322  Systemic lupus erythematosus
epz05323  Rheumatoid arthritis
epz05330  Allograft rejection
epz05332  Graft-versus-host disease
epz05410  Hypertrophic cardiomyopathy
epz05414  Dilated cardiomyopathy
epz05417  Lipid and atherosclerosis
epz05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:epz00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103562469 (TNF)
   04350 TGF-beta signaling pathway
    103562469 (TNF)
   04064 NF-kappa B signaling pathway
    103562469 (TNF)
   04668 TNF signaling pathway
    103562469 (TNF)
   04071 Sphingolipid signaling pathway
    103562469 (TNF)
   04150 mTOR signaling pathway
    103562469 (TNF)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    103562469 (TNF)
   04061 Viral protein interaction with cytokine and cytokine receptor
    103562469 (TNF)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    103562469 (TNF)
   04217 Necroptosis
    103562469 (TNF)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    103562469 (TNF)
   04620 Toll-like receptor signaling pathway
    103562469 (TNF)
   04621 NOD-like receptor signaling pathway
    103562469 (TNF)
   04622 RIG-I-like receptor signaling pathway
    103562469 (TNF)
   04625 C-type lectin receptor signaling pathway
    103562469 (TNF)
   04650 Natural killer cell mediated cytotoxicity
    103562469 (TNF)
   04612 Antigen processing and presentation
    103562469 (TNF)
   04660 T cell receptor signaling pathway
    103562469 (TNF)
   04657 IL-17 signaling pathway
    103562469 (TNF)
   04664 Fc epsilon RI signaling pathway
    103562469 (TNF)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    103562469 (TNF)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    103562469 (TNF)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    103562469 (TNF)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    103562469 (TNF)
   05170 Human immunodeficiency virus 1 infection
    103562469 (TNF)
   05161 Hepatitis B
    103562469 (TNF)
   05160 Hepatitis C
    103562469 (TNF)
   05171 Coronavirus disease - COVID-19
    103562469 (TNF)
   05164 Influenza A
    103562469 (TNF)
   05168 Herpes simplex virus 1 infection
    103562469 (TNF)
   05163 Human cytomegalovirus infection
    103562469 (TNF)
   05169 Epstein-Barr virus infection
    103562469 (TNF)
   05165 Human papillomavirus infection
    103562469 (TNF)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103562469 (TNF)
   05135 Yersinia infection
    103562469 (TNF)
   05133 Pertussis
    103562469 (TNF)
   05134 Legionellosis
    103562469 (TNF)
   05152 Tuberculosis
    103562469 (TNF)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    103562469 (TNF)
   05144 Malaria
    103562469 (TNF)
   05145 Toxoplasmosis
    103562469 (TNF)
   05140 Leishmaniasis
    103562469 (TNF)
   05142 Chagas disease
    103562469 (TNF)
   05143 African trypanosomiasis
    103562469 (TNF)
  09163 Immune disease
   05310 Asthma
    103562469 (TNF)
   05322 Systemic lupus erythematosus
    103562469 (TNF)
   05323 Rheumatoid arthritis
    103562469 (TNF)
   05321 Inflammatory bowel disease
    103562469 (TNF)
   05330 Allograft rejection
    103562469 (TNF)
   05332 Graft-versus-host disease
    103562469 (TNF)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    103562469 (TNF)
   05014 Amyotrophic lateral sclerosis
    103562469 (TNF)
   05020 Prion disease
    103562469 (TNF)
   05022 Pathways of neurodegeneration - multiple diseases
    103562469 (TNF)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103562469 (TNF)
   05418 Fluid shear stress and atherosclerosis
    103562469 (TNF)
   05410 Hypertrophic cardiomyopathy
    103562469 (TNF)
   05414 Dilated cardiomyopathy
    103562469 (TNF)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    103562469 (TNF)
   04940 Type I diabetes mellitus
    103562469 (TNF)
   04936 Alcoholic liver disease
    103562469 (TNF)
   04932 Non-alcoholic fatty liver disease
    103562469 (TNF)
   04931 Insulin resistance
    103562469 (TNF)
   04933 AGE-RAGE signaling pathway in diabetic complications
    103562469 (TNF)
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    103562469 (TNF)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:epz04052]
    103562469 (TNF)
   00536 Glycosaminoglycan binding proteins [BR:epz00536]
    103562469 (TNF)
Cytokines and neuropeptides [BR:epz04052]
 Cytokines
  Tumor necrosis fators
   103562469 (TNF)
Glycosaminoglycan binding proteins [BR:epz00536]
 Heparan sulfate / Heparin
  Cytokines
   103562469 (TNF)
SSDB
Motif
Pfam: TNF
Other DBs
NCBI-GeneID: 103562469
NCBI-ProteinID: XP_008535731
UniProt: A0ABM2FFH7
LinkDB
Position
19:31797318..31800122
AA seq 253 aa
MPQGSTISQLDLSPSGKDIMSTESMIRDVELAEEELAKKAGGPQGSRRCLCLSLFSFLLV
AGATTLFCLLHFGVIGPQREEQLPNAFQSINPLAQTLRSSSRTPSDKPVAHVVANPQAEG
QLQWLSGRANALLANGVKLTDNQLVVPLDGLYLIYSQVLFKGQGCPSTHVLLTHTISRLA
VSYPSKVNLLSAIKSPCHTESPEQAEAKPWYEPIYLGGVFQLEKGDQLSAEINQPNYLDF
AESGQVYFGIIAL
NT seq 762 nt   +upstreamnt  +downstreamnt
atgccccagggctcgaccatctcccagctggacttgagcccctctggaaaggacatcatg
agcactgaaagcatgatccgagatgtggagctggcagaggaggagctcgccaagaaggca
gggggcccccagggctccagacggtgcttgtgcctcagcctcttctccttcctccttgtc
gcaggagccaccacgctcttctgcctgctgcactttggggtgatcggcccccagagggaa
gagcagttaccgaatgccttccagtcaatcaaccctctggcccagacactcagatcatct
tctcgaaccccaagtgacaagcctgtagcccatgttgtagcaaacccccaagccgagggg
cagctccagtggctgagtgggcgtgcaaatgccctcctggccaatggcgtgaagctgaca
gacaaccagctggtggtaccattggatgggctgtacctcatctactcccaggtcctcttc
aaaggccaaggctgcccttccacccatgtgctcctcacccacaccatcagccgcttagct
gtctcctacccgtccaaggtcaacctcctctctgccatcaagagcccttgccacacggag
tccccagagcaggctgaagccaagccctggtatgagcccatctacctgggaggagtcttc
cagctggagaagggtgatcaactcagcgctgagatcaatcagcccaactatctcgacttt
gcggagtccgggcaggtctactttgggatcattgccctgtga

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