Eulemur rufifrons (Bennett's brown lemur): 138375648
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Entry
138375648 CDS
T11398
Symbol
HSD11B1
Name
(RefSeq) 11-beta-hydroxysteroid dehydrogenase 1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
eruf Eulemur rufifrons (Bennett's brown lemur)
Pathway
eruf00140
Steroid hormone biosynthesis
eruf00980
Metabolism of xenobiotics by cytochrome P450
eruf01100
Metabolic pathways
eruf05204
Chemical carcinogenesis - DNA adducts
Module
eruf_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
eruf00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
138375648 (HSD11B1)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
138375648 (HSD11B1)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
138375648 (HSD11B1)
Enzymes [BR:
eruf01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
138375648 (HSD11B1)
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Motif
Pfam:
adh_short
adh_short_C2
KR
DUF1776
THF_DHG_CYH_C
FMO-like
2-Hacid_dh_C
Shikimate_DH
Pyr_redox_2
Pyr_redox_3
Motif
Other DBs
NCBI-GeneID:
138375648
NCBI-ProteinID:
XP_069315509
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All DBs
Position
27:complement(25075716..25115281)
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AA seq
292 aa
AA seq
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MAFMKKYLLPALGLLLAYNYYSANEKFRPEMLQGKRVIVTGASKGIGEEMAYHLARMGAH
VVLTARSKENLQKVVSRCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLLGGLDMLILNH
ITNTSLNFFHDDIPHVRKSMEVNFLSYVVLSVAALPMLKQSNGSIAVISSIAGKMAHPLI
ASYSASKFALDGFFSSLRKEHSVAKVNVSITLCVLGLINTDTAMKAVSGVLAKQAAPKEE
CALEIIKGTALRQEEIYYDSSLWTSFLLGNPGRKIMEFTVLSYYNMDRFTNN
NT seq
879 nt
NT seq
+upstream
nt +downstream
nt
atggcttttatgaaaaaatatctccttcccgctctggggctcctcttggcctacaactac
tattctgcaaatgagaaattcagaccagagatgctccaaggaaagagagtgattgtcaca
ggggccagcaaagggatcggagaagagatggcttatcacctggccaggatgggagcgcat
gttgttttgacagcgaggtcaaaagaaaatctacaaaaggtggtatcccgctgcctggag
cttggagcggcctcagcacactacattgctggtaccatggaagacatgaccttcgcagag
caatttgttgcccaagcaggaaagctcctggggggactggacatgctcattctcaaccac
atcaccaacacttctttgaatttttttcatgatgatattccccacgtgcgcaaaagcatg
gaggtcaacttcctcagctatgtggtcctgagtgtagctgccttgcccatgctgaagcag
agcaatggaagcattgcagtcatctcctcgatcgctgggaaaatggctcatccactgatt
gcttcctattctgcaagcaagtttgctctggatgggttcttctcctccctcaggaaggaa
cactcagtggccaaggtcaatgtgtcaatcactctctgtgttctcggcctcataaacaca
gatacagccatgaaggcagtttctggggtactggctaaacaagcagctccaaaggaggaa
tgtgccctggagatcatcaaagggacagctctgcgccaagaggaaatatattatgacagc
tcactctggacctctttcctgctaggaaatccagggaggaaaataatggaatttaccgtc
ttaagttactataatatggacagattcacaaacaactag
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