Eulemur rufifrons (Bennett's brown lemur): 138387509
Help
Entry
138387509 CDS
T11398
Symbol
IRS1
Name
(RefSeq) insulin receptor substrate 1
KO
K16172
insulin receptor substrate 1
Organism
eruf Eulemur rufifrons (Bennett's brown lemur)
Pathway
eruf04022
cGMP-PKG signaling pathway
eruf04068
FoxO signaling pathway
eruf04081
Hormone signaling
eruf04140
Autophagy - animal
eruf04150
mTOR signaling pathway
eruf04151
PI3K-Akt signaling pathway
eruf04152
AMPK signaling pathway
eruf04211
Longevity regulating pathway
eruf04213
Longevity regulating pathway - multiple species
eruf04722
Neurotrophin signaling pathway
eruf04910
Insulin signaling pathway
eruf04920
Adipocytokine signaling pathway
eruf04923
Regulation of lipolysis in adipocytes
eruf04930
Type II diabetes mellitus
eruf04931
Insulin resistance
eruf04932
Non-alcoholic fatty liver disease
eruf04935
Growth hormone synthesis, secretion and action
eruf04960
Aldosterone-regulated sodium reabsorption
eruf05010
Alzheimer disease
eruf05206
MicroRNAs in cancer
eruf05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
eruf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
138387509 (IRS1)
04022 cGMP-PKG signaling pathway
138387509 (IRS1)
04151 PI3K-Akt signaling pathway
138387509 (IRS1)
04152 AMPK signaling pathway
138387509 (IRS1)
04150 mTOR signaling pathway
138387509 (IRS1)
09133 Signaling molecules and interaction
04081 Hormone signaling
138387509 (IRS1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
138387509 (IRS1)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
138387509 (IRS1)
04923 Regulation of lipolysis in adipocytes
138387509 (IRS1)
04920 Adipocytokine signaling pathway
138387509 (IRS1)
04935 Growth hormone synthesis, secretion and action
138387509 (IRS1)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
138387509 (IRS1)
09156 Nervous system
04722 Neurotrophin signaling pathway
138387509 (IRS1)
09149 Aging
04211 Longevity regulating pathway
138387509 (IRS1)
04213 Longevity regulating pathway - multiple species
138387509 (IRS1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
138387509 (IRS1)
09164 Neurodegenerative disease
05010 Alzheimer disease
138387509 (IRS1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
138387509 (IRS1)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
138387509 (IRS1)
04932 Non-alcoholic fatty liver disease
138387509 (IRS1)
04931 Insulin resistance
138387509 (IRS1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
IRS
PH
PH_11
Motif
Other DBs
NCBI-GeneID:
138387509
NCBI-ProteinID:
XP_069330717
LinkDB
All DBs
Position
1:11115538..11173283
Genome browser
AA seq
1236 aa
AA seq
DB search
MASPSETDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAP
KRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKGH
HDGASAPGVGGGGSCSGSSGLGEAGEDLSYGDAPPGPAFKEVWQVILKPKGLGQTKNLIG
IYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQVD
DSVVAQNMHETILEAMRAMSDEFRPRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLTR
RSRTESITATSPASMVGGKPGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHRG
SARLHPPLNHSRSIPMPSSRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSPS
DGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGASTLTAPNG
HYILSRGGNGHRYIPGAGLGTSPALAGDEAASASDLDNRFRKRTHSAGTSPTISHQKTPS
QSSVASIEEYTEMMPAYPPGGGSGGRLPGHRHSAFVPTHSYPEEGLEMHPLEPQGGHHRP
DTSTLHTDDGYMPMSPGVAPVPGSRKGSGDYMPMSPKSVSAPQQIINPIRRHPQRVDPNG
YMMMSPSGSCSPDLGGGPSSSSSAAPSGSSYGKLWTNGVGGHHSPALPHPKPPVESSGGK
LLPCTGDYMNMSPVGDSNTSSPSGCYYGPEYPQHKPVLSYYSLPRSFKHTQRPGEPEEGG
RHQHLRLSSSSGRLLYAATAEDSSSSTSSDSLGGGYCGARLEPGLPHAHHHILQAHLPRK
VDTAAQTNSRLARPTRLSLGDPKASTLPRAREQQQPLLHPPEPKSPGEYVNIEFGSDQPG
YLSGPVASHSSPSVRCPSQLQPTPREEETGTEEYMKMDLGPGRRAAWQESSRAEMGRVGP
APPGATSVCRPTRAVPSSRGDYMTMQMGCPRQSYVDTSPVAPVSYADMRTGIAAQEVSLP
RAATAAPSSSSAASASPAAPQGTAELAARSSLLGGPQGPGGMSAFTRVNLSPNRNQSAKV
IRADPQGCRRRHSSETFSSTPSATRVGNTVPFGGGAAVGASSGGGSSSEDVKRHSSASFE
NVWLKPGELGEAPKESAQVCGAAAGGLENGLNYIDLDLVKDFKQRPQERPPQPQPPPPTP
PHQPLGSGESSSPRRSSEDLSAYASISFQKQPEDRQ
NT seq
3711 nt
NT seq
+upstream
nt +downstream
nt
atggcgagcccttcggagaccgacggcttctcggatgtgcgcaaggttggctacctgcgc
aaacccaagagcatgcacaagcgcttcttcgtgctacgggcggccagcgaggctgggggc
ccggcgcgcctggagtactacgagaacgagaagaagtggcggcacaagtcgagcgccccc
aaacgctctatcccccttgagagctgcttcaacatcaacaagcgggctgactccaagaac
aagcacctggtagctctctatacccgggacgagcactttgccatcgcggcggacagcgag
gccgagcaagacagctggtaccaggctcttctgcagctgcacaaccgtgccaagggccac
cacgatggggcttcagcccccggagtgggaggcgggggcagctgcagcggcagctctggc
ctgggcgaggctggggaggacttgagctatggggatgcgcccccaggacccgccttcaaa
gaggtctggcaggtgatcctgaagcccaagggcctgggtcagacaaagaacttgattggc
atctaccgcctctgcctgaccagcaagaccatcagcttcgtgaagctgaactctgaggca
gcggcagtggtgctgcagctaatgaacatcaggcgctgcggccactcggagaacttcttc
ttcatcgaggtgggccgttccgccgtgacggggcccggggagttctggatgcaggtggat
gactcagtggtggcccagaacatgcacgagaccatcctggaggccatgcgggccatgagt
gatgagttccgccctcgcagcaagagccagtcctcatccaactgctccaaccccatcagc
gtccccctgcgcaggcaccatctcaacaaccccccgcctagccaggtggggctaacccgc
cgttcgcgcaccgagagcatcaccgccacctccccagccagcatggtgggcgggaagcca
ggttcctttcgcgtccgcgcctccagcgatggcgaaggcaccatgtcccgcccagcctcg
gtggatggcagccctgtgagtcccagcaccaataggacccacgcccaccggcatcggggc
agcgcccggctgcaccccccactcaatcacagccgctctatccccatgccttcttctcgc
tgctcgccttcggccaccagcccggtcagtctgtcgtccagcagcaccagtggccatggc
tccacctcggattgtctgttcccacggcggtctagtgcttctgtgtccgggtcccccagc
gacggcggtttcatctcctcggatgagtatggctccagtccctgcgatttccgaagttct
ttccgcagtgtcactccagattccctgggccacaccccaccagcccgtggtgaagaggag
ctgagcaactatatctgcatgggcggcaagggggcctccaccctgaccgcccccaacggt
cactacattttgtctcggggtggcaatggccaccgctacatcccgggagctggcttgggc
accagtccagccttggctggggatgaagcagccagtgcttcagatctggataatcggttc
cgaaagagaactcactcggcaggcacatcccctaccatttcccaccagaagaccccgtcc
cagtcctcagtggcttccattgaggagtatacggagatgatgcctgcttacccaccagga
ggtggcagtggaggccgactgccgggccaccggcactccgccttcgtgcccacccactcc
tacccggaggagggtctggaaatgcaccccttggagcctcaggggggccaccaccgccca
gatacctccaccctccacaccgacgatggctatatgcccatgtccccgggggtagccccc
gtgccgggcagcagaaagggcagtggcgactatatgcccatgagccccaagagcgtgtct
gccccccagcagatcatcaaccccatcagacgccatccccagagagtggaccccaatggc
tacatgatgatgtcccccagcggcagctgctcccctgaccttggaggtgggcccagcagc
agcagcagcgctgccccctctgggagcagctatgggaagctttggacaaatggcgtaggg
ggccaccactctcccgccctgccccaccccaagcctcccgtggagagcagtggtggcaag
cttttgccttgcacaggtgactacatgaacatgtcgccagtgggggactccaataccagc
agcccctccggctgctactatggccctgagtacccccagcacaagccagtgctctcctac
tactcattgccaaggtcctttaagcacacccagcgtcctggggagccggaagagggtggc
cggcaccagcacctccgcctttcctctagctctggtcgccttctctatgccgcaacagca
gaagattcttcttcctccaccagcagcgacagccttggtgggggatactgtggggccagg
ctggagcctggtctcccgcatgcccaccatcacatcctgcaggcccatctgcctcgaaaa
gtggacacagctgcccagaccaacagccgcctggctcggcccacgaggctatccctgggg
gatcccaaggccagcactttacctcgggcccgagagcagcagcagcccctgctgcaccct
ccggagcccaaaagcccaggggaatatgtgaatattgaatttgggagtgatcagcctggc
tatttatctggccccgtggcttcccacagctcgccttcagtcaggtgtccatcccagctc
cagccaactcccagagaggaagagactggcactgaggagtacatgaaaatggacctgggg
ccgggccggagggcagcctggcaggagagctccagggctgagatgggcagagtgggcccc
gcacctcccggggctactagcgtttgcaggcccacccgggcagtacccagcagccggggc
gactacatgaccatgcagatgggttgtccccgtcagagctacgtggacacctccccagtt
gcccctgtcagctatgctgacatgcggacaggcattgctgcacaggaagtgagcctgccc
agggctgccacggctgctccctcctcatcctcagcagcctctgcttctcctgctgcacct
caagggacagctgagctggctgcccgatcatccctgctagggggcccacagggacccggg
ggcatgagcgccttcaccagggtgaacctcagtcccaaccgcaaccagagtgccaaagtg
atccgtgcagacccacaagggtgccggaggaggcatagctccgagaccttctcctccaca
cctagtgccacccgggtgggcaacacggtgcccttcggagggggcgctgcagtaggggct
agcagcggaggcggcagcagcagtgaggatgtgaaacgccacagctctgcttcctttgag
aatgtgtggctgaagcctggggagcttggggaagcccccaaggagtcagcccaagtgtgt
ggggctgctgctgggggtttggagaatggtcttaactacatagacctggatttggtcaag
gacttcaagcagcgccctcaggagcgcccccctcaaccgcagcctcccccaccaacgccc
cctcatcagcccctgggcagtggtgagagcagctccccccgccgctccagtgaggattta
agcgcctatgccagcatcagtttccagaagcagccagaggaccgccagtag
DBGET
integrated database retrieval system
