KEGG   Eulemur rufifrons (Bennett's brown lemur): 138390622
Entry
138390622         CDS       T11398                                 
Name
(RefSeq) phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1
  KO
K02649  phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Organism
eruf  Eulemur rufifrons (Bennett's brown lemur)
Pathway
eruf01521  EGFR tyrosine kinase inhibitor resistance
eruf01522  Endocrine resistance
eruf01524  Platinum drug resistance
eruf04012  ErbB signaling pathway
eruf04014  Ras signaling pathway
eruf04015  Rap1 signaling pathway
eruf04024  cAMP signaling pathway
eruf04062  Chemokine signaling pathway
eruf04066  HIF-1 signaling pathway
eruf04068  FoxO signaling pathway
eruf04070  Phosphatidylinositol signaling system
eruf04071  Sphingolipid signaling pathway
eruf04072  Phospholipase D signaling pathway
eruf04081  Hormone signaling
eruf04140  Autophagy - animal
eruf04145  Phagocytosis
eruf04150  mTOR signaling pathway
eruf04151  PI3K-Akt signaling pathway
eruf04152  AMPK signaling pathway
eruf04210  Apoptosis
eruf04211  Longevity regulating pathway
eruf04213  Longevity regulating pathway - multiple species
eruf04218  Cellular senescence
eruf04360  Axon guidance
eruf04370  VEGF signaling pathway
eruf04380  Osteoclast differentiation
eruf04510  Focal adhesion
eruf04517  IgSF CAM signaling
eruf04518  Integrin signaling
eruf04550  Signaling pathways regulating pluripotency of stem cells
eruf04611  Platelet activation
eruf04613  Neutrophil extracellular trap formation
eruf04620  Toll-like receptor signaling pathway
eruf04625  C-type lectin receptor signaling pathway
eruf04630  JAK-STAT signaling pathway
eruf04650  Natural killer cell mediated cytotoxicity
eruf04660  T cell receptor signaling pathway
eruf04662  B cell receptor signaling pathway
eruf04664  Fc epsilon RI signaling pathway
eruf04666  Fc gamma R-mediated phagosome formation
eruf04668  TNF signaling pathway
eruf04670  Leukocyte transendothelial migration
eruf04722  Neurotrophin signaling pathway
eruf04725  Cholinergic synapse
eruf04750  Inflammatory mediator regulation of TRP channels
eruf04810  Regulation of actin cytoskeleton
eruf04910  Insulin signaling pathway
eruf04914  Progesterone-mediated oocyte maturation
eruf04915  Estrogen signaling pathway
eruf04917  Prolactin signaling pathway
eruf04919  Thyroid hormone signaling pathway
eruf04923  Regulation of lipolysis in adipocytes
eruf04926  Relaxin signaling pathway
eruf04929  GnRH secretion
eruf04930  Type II diabetes mellitus
eruf04931  Insulin resistance
eruf04932  Non-alcoholic fatty liver disease
eruf04933  AGE-RAGE signaling pathway in diabetic complications
eruf04935  Growth hormone synthesis, secretion and action
eruf04960  Aldosterone-regulated sodium reabsorption
eruf04973  Carbohydrate digestion and absorption
eruf05010  Alzheimer disease
eruf05017  Spinocerebellar ataxia
eruf05020  Prion disease
eruf05100  Bacterial invasion of epithelial cells
eruf05135  Yersinia infection
eruf05142  Chagas disease
eruf05146  Amoebiasis
eruf05160  Hepatitis C
eruf05161  Hepatitis B
eruf05162  Measles
eruf05163  Human cytomegalovirus infection
eruf05164  Influenza A
eruf05165  Human papillomavirus infection
eruf05166  Human T-cell leukemia virus 1 infection
eruf05167  Kaposi sarcoma-associated herpesvirus infection
eruf05168  Herpes simplex virus 1 infection
eruf05169  Epstein-Barr virus infection
eruf05170  Human immunodeficiency virus 1 infection
eruf05171  Coronavirus disease
eruf05200  Pathways in cancer
eruf05203  Viral carcinogenesis
eruf05205  Proteoglycans in cancer
eruf05206  MicroRNAs in cancer
eruf05207  Chemical carcinogenesis - receptor activation
eruf05208  Chemical carcinogenesis - reactive oxygen species
eruf05210  Colorectal cancer
eruf05211  Renal cell carcinoma
eruf05212  Pancreatic cancer
eruf05213  Endometrial cancer
eruf05214  Glioma
eruf05215  Prostate cancer
eruf05218  Melanoma
eruf05220  Chronic myeloid leukemia
eruf05221  Acute myeloid leukemia
eruf05222  Small cell lung cancer
eruf05223  Non-small cell lung cancer
eruf05224  Breast cancer
eruf05225  Hepatocellular carcinoma
eruf05226  Gastric cancer
eruf05230  Central carbon metabolism in cancer
eruf05231  Choline metabolism in cancer
eruf05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
eruf05415  Diabetic cardiomyopathy
eruf05417  Lipid and atherosclerosis
eruf05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:eruf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    138390622
   04014 Ras signaling pathway
    138390622
   04015 Rap1 signaling pathway
    138390622
   04370 VEGF signaling pathway
    138390622
   04630 JAK-STAT signaling pathway
    138390622
   04668 TNF signaling pathway
    138390622
   04066 HIF-1 signaling pathway
    138390622
   04068 FoxO signaling pathway
    138390622
   04070 Phosphatidylinositol signaling system
    138390622
   04072 Phospholipase D signaling pathway
    138390622
   04071 Sphingolipid signaling pathway
    138390622
   04024 cAMP signaling pathway
    138390622
   04151 PI3K-Akt signaling pathway
    138390622
   04152 AMPK signaling pathway
    138390622
   04150 mTOR signaling pathway
    138390622
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    138390622
   04517 IgSF CAM signaling
    138390622
   04518 Integrin signaling
    138390622
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    138390622
   04140 Autophagy - animal
    138390622
  09143 Cell growth and death
   04210 Apoptosis
    138390622
   04218 Cellular senescence
    138390622
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    138390622
   04550 Signaling pathways regulating pluripotency of stem cells
    138390622
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    138390622
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    138390622
   04613 Neutrophil extracellular trap formation
    138390622
   04620 Toll-like receptor signaling pathway
    138390622
   04625 C-type lectin receptor signaling pathway
    138390622
   04650 Natural killer cell mediated cytotoxicity
    138390622
   04660 T cell receptor signaling pathway
    138390622
   04662 B cell receptor signaling pathway
    138390622
   04664 Fc epsilon RI signaling pathway
    138390622
   04666 Fc gamma R-mediated phagosome formation
    138390622
   04670 Leukocyte transendothelial migration
    138390622
   04062 Chemokine signaling pathway
    138390622
  09152 Endocrine system
   04910 Insulin signaling pathway
    138390622
   04923 Regulation of lipolysis in adipocytes
    138390622
   04929 GnRH secretion
    138390622
   04915 Estrogen signaling pathway
    138390622
   04914 Progesterone-mediated oocyte maturation
    138390622
   04917 Prolactin signaling pathway
    138390622
   04926 Relaxin signaling pathway
    138390622
   04935 Growth hormone synthesis, secretion and action
    138390622
   04919 Thyroid hormone signaling pathway
    138390622
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    138390622
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    138390622
  09156 Nervous system
   04725 Cholinergic synapse
    138390622
   04722 Neurotrophin signaling pathway
    138390622
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    138390622
  09158 Development and regeneration
   04360 Axon guidance
    138390622
   04380 Osteoclast differentiation
    138390622
  09149 Aging
   04211 Longevity regulating pathway
    138390622
   04213 Longevity regulating pathway - multiple species
    138390622
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    138390622
   05206 MicroRNAs in cancer
    138390622
   05205 Proteoglycans in cancer
    138390622
   05207 Chemical carcinogenesis - receptor activation
    138390622
   05208 Chemical carcinogenesis - reactive oxygen species
    138390622
   05203 Viral carcinogenesis
    138390622
   05230 Central carbon metabolism in cancer
    138390622
   05231 Choline metabolism in cancer
    138390622
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    138390622
  09162 Cancer: specific types
   05210 Colorectal cancer
    138390622
   05212 Pancreatic cancer
    138390622
   05225 Hepatocellular carcinoma
    138390622
   05226 Gastric cancer
    138390622
   05214 Glioma
    138390622
   05221 Acute myeloid leukemia
    138390622
   05220 Chronic myeloid leukemia
    138390622
   05218 Melanoma
    138390622
   05211 Renal cell carcinoma
    138390622
   05215 Prostate cancer
    138390622
   05213 Endometrial cancer
    138390622
   05224 Breast cancer
    138390622
   05222 Small cell lung cancer
    138390622
   05223 Non-small cell lung cancer
    138390622
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    138390622
   05170 Human immunodeficiency virus 1 infection
    138390622
   05161 Hepatitis B
    138390622
   05160 Hepatitis C
    138390622
   05171 Coronavirus disease
    138390622
   05164 Influenza A
    138390622
   05162 Measles
    138390622
   05168 Herpes simplex virus 1 infection
    138390622
   05163 Human cytomegalovirus infection
    138390622
   05167 Kaposi sarcoma-associated herpesvirus infection
    138390622
   05169 Epstein-Barr virus infection
    138390622
   05165 Human papillomavirus infection
    138390622
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    138390622
   05100 Bacterial invasion of epithelial cells
    138390622
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    138390622
   05142 Chagas disease
    138390622
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    138390622
   05017 Spinocerebellar ataxia
    138390622
   05020 Prion disease
    138390622
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    138390622
   05418 Fluid shear stress and atherosclerosis
    138390622
   05415 Diabetic cardiomyopathy
    138390622
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    138390622
   04932 Non-alcoholic fatty liver disease
    138390622
   04931 Insulin resistance
    138390622
   04933 AGE-RAGE signaling pathway in diabetic complications
    138390622
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    138390622
   01524 Platinum drug resistance
    138390622
   01522 Endocrine resistance
    138390622
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:eruf04131]
    138390622
Membrane trafficking [BR:eruf04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    138390622
SSDB
Motif
Pfam: PI3K_P85_iSH2 SH2 SH2_1 DicA_C ODF2_C Exonuc_VII_L
Other DBs
NCBI-GeneID: 138390622
NCBI-ProteinID: XP_069336011
LinkDB
Position
8:complement(33472233..33610228)
AA seq 507 aa
MGPSSLVHAPRPRGMSSSHRRPGMGWPRPRFPRMFKRSRRRYRKKPQAPTATSAATNLAT
MVTEINNTHTATTRVWILPSQALPPKPPKPMTSAVTNGMKDSSVSLQDAEWYWGDISREE
VNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDGKYGFSDPLTFNSVV
ELINHYHHESLAQYNPKLDVKLTYPVSRYQQDQLVKEDNIDAVGKKLQEYHSQYQEKSKE
YDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQHSKEYIERFRREGNEKEIE
RIMMNYDKLKSRLGEIHDSKMRLEQDLKKQALDNREIDKKMNSIKPDLIQLRKIRDQHLV
WLNHKGVRQKRLNAWLGIKNEDADENYFINEEDENLPHYDEKTWFVEDINRVQAEDLLYG
KPDGAFLIRESSKKGCYACSVVADGEVKHCVIYSTARGYGFAEPYNLYSSLKELVLHYQQ
TSLVQHNDSLNVRLAYPVYAQMPSLCR
NT seq 1524 nt   +upstreamnt  +downstreamnt
atggggccctcttcgcttgtccatgccccccggccccggggcatgagttcctcccaccgc
aggccaggtatgggctggcccaggccccggtttcccaggatgtttaagcgcagccgcaga
aggtaccggaagaaaccccaagccccaactgccaccagtgcagccaccaatcttgccacc
atggtcacagagatcaacaacacccacactgccaccaccagggtgtggatcttaccatct
caagctcttccaccaaagccacctaagccaatgacgtcagcagttacaaatggaatgaag
gacagttctgtttctcttcaggatgcagaatggtactggggagatatttcaagggaggag
gtgaatgacaagttacgggacatgcccgatggtaccttcttggttcgagatgcatcaaca
aaaatgcagggagattatactttgactttgcggaagggaggcaataataagttaataaag
atctatcatcgggatggtaaatatggtttttctgatcctctgacatttaattctgtggtg
gagctcattaaccactatcatcatgaatctcttgctcagtacaatcccaaacttgatgtg
aagctgacgtacccagtgtccagataccaacaggatcagttggtaaaagaagataacatt
gatgcagtaggtaaaaaactgcaagagtaccactctcagtatcaggaaaagagtaaagag
tatgataggctatatgaagaatataccagaacatcccaggaaatacagatgaagaggact
gcaattgaagcttttaatgaaacaattaaaatatttgaggaacagtgtcacacacaagaa
caacacagcaaagaatatattgagcgatttcgcagagaggggaatgaaaaggagattgaa
cgaattatgatgaattatgataaattgaaatcccgtctgggtgagattcatgatagcaaa
atgcgtctagagcaggatttgaagaaacaagctttggacaaccgagaaatagataaaaaa
atgaatagtatcaaacctgacctgatacagctgcgcaagatccgagatcagcaccttgta
tggctcaatcacaaaggagtgagacagaagcgcctgaatgcgtggctgggaatcaagaat
gaggatgctgatgagaactattttatcaatgaggaagacgaaaacctgccccattatgat
gagaagacctggtttgtggaggatatcaatcgagttcaagcagaggatttgctttacggg
aaacctgatggcgcattcttaattcgtgagagcagcaagaaaggatgctatgcttgctct
gtggttgccgatggggaagtgaagcactgtgtgatctacagcactgctcggggctatggc
tttgcagagccctacaacctgtacagctctctgaaagagctggtgctccattaccagcag
acatccctggttcagcacaacgactccctcaacgtcaggcttgcctaccctgtctatgca
cagatgccctcgctctgcagataa

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