Escherichia coli O104 H4 2011C-3493 (EAEC): O3K_06430
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Entry
O3K_06430 CDS
T02257
Symbol
tyrA
Name
(GenBank) bifunctional chorismate mutase/prephenate dehydrogenase
KO
K14187
chorismate mutase / prephenate dehydrogenase [EC:
5.4.99.5
1.3.1.12
]
Organism
esl
Escherichia coli O104:H4 2011C-3493 (EAEC)
Pathway
esl00400
Phenylalanine, tyrosine and tryptophan biosynthesis
esl00401
Novobiocin biosynthesis
esl01100
Metabolic pathways
esl01110
Biosynthesis of secondary metabolites
esl01230
Biosynthesis of amino acids
Module
esl_M00024
Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine
esl_M00025
Tyrosine biosynthesis, chorismate => HPP => tyrosine
Brite
KEGG Orthology (KO) [BR:
esl00001
]
09100 Metabolism
09105 Amino acid metabolism
00400 Phenylalanine, tyrosine and tryptophan biosynthesis
O3K_06430 (tyrA)
09110 Biosynthesis of other secondary metabolites
00401 Novobiocin biosynthesis
O3K_06430 (tyrA)
Enzymes [BR:
esl01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.12 prephenate dehydrogenase
O3K_06430 (tyrA)
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.5 chorismate mutase
O3K_06430 (tyrA)
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Motif
Pfam:
CM_2
PDH_N
PDH_C
F420_oxidored
Motif
Other DBs
NCBI-ProteinID:
AFS73193
UniProt:
A0A0E0XVG3
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Position
1319314..1320435
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AA seq
373 aa
AA seq
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MVAELTALRDQIDEVDKALLNLLAKRLELVAEVGEVKSRFGLPIYVPEREASMLASRRAE
AEALGVPPDLIEDVLRRMMRESYSSENDKGFKTLCPSLRPVVIVGGGGQMGRLFEKMLTL
SGYQVRILEQHDWDRAADIVADAGMVIVSVPIHVTEQVIGKLPPLPKDCILVDLASVKNG
PLQAMLAAHDGPVLGLHPMFGPDSGSLAKQVVVWCDGRKPEAYQWFLEQIQVWGARLHRI
SAVEHDQNMAFIQALRHFATFAYGLHLAEENVQLEQLLALSSPIYRLELAMVGRLFAQDP
QLYADIIMSSERNLALIKRYYKRFGEAIELLEQGDKQAFIDSFRKVEHWFGDYAQRFQSE
SRVLLRQANDNRQ
NT seq
1122 nt
NT seq
+upstream
nt +downstream
nt
atggttgctgaattgaccgcattacgcgatcaaattgatgaagtcgataaagcgctgctg
aatttattagcgaagcgtctggaactggttgctgaagtgggcgaggtgaaaagccgcttt
ggactgcctatttatgttccggagcgcgaggcatctatgttggcctcgcgtcgtgcagag
gcggaagctctgggtgtaccgccagatctgattgaggatgttttgcgtcggatgatgcgt
gaatcttactccagtgaaaacgacaaaggatttaaaacactttgtccgtcactgcgtccg
gtggttatcgtcggcggtggcggtcagatgggacgcctgttcgagaagatgctgacacta
tcgggttatcaggtgcggattctggagcaacatgactgggatcgagcggctgatattgtt
gccgatgccggaatggtgattgttagtgtgccaatccacgttactgagcaagttatcggc
aaattaccgcctttaccgaaagattgtattcttgttgatctggcatcagtgaaaaatgga
ccattacaggccatgctggcggcgcacgatggcccggtactggggttacacccgatgttc
ggcccggacagcggtagcctggcaaagcaagttgtggtctggtgtgatggacgtaagccg
gaagcataccaatggtttctggagcaaattcaggtctggggcgctcggctgcatcgtatt
agcgctgtcgagcacgatcagaatatggcgtttattcaggctctgcgccactttgctact
tttgcttatgggctgcatctggcagaagaaaatgttcagcttgagcaacttctggcgctc
tcttcgccgatttaccgccttgagctggcgatggtcgggcgactgtttgctcaggatccg
cagctttatgccgacattattatgtcgtcagagcgtaatctggcgttaatcaaacgttac
tataagcgtttcggcgaggcgattgagttgctggagcagggcgataagcaggcgtttatt
gacagtttccgcaaggtggagcactggttcggcgattacgcacagcgttttcagagtgaa
agccgcgtgttattgcgtcaggcgaatgacaaccgccagtaa
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