KEGG   Escherichia coli O104 H4 2009EL-2050 (EAEC): O3M_21205
Entry
O3M_21205         CDS       T02316                                 
Symbol
folA
Name
(GenBank) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
esm  Escherichia coli O104:H4 2009EL-2050 (EAEC)
Pathway
esm00670  One carbon pool by folate
esm00790  Folate biosynthesis
esm01100  Metabolic pathways
esm01240  Biosynthesis of cofactors
esm04981  Folate transport and metabolism
Module
esm_M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:esm00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    O3M_21205 (folA)
   00670 One carbon pool by folate
    O3M_21205 (folA)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    O3M_21205 (folA)
Enzymes [BR:esm01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     O3M_21205 (folA)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: AFS58902
LinkDB
Position
complement(4376027..4376506)
AA seq 159 aa
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNI
ILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVE
GDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
NT seq 480 nt   +upstreamnt  +downstreamnt
atgatcagtctgattgcggcgttagcggtagatcgcgttatcggcatggaaaacgccatg
ccgtggaacctgcctgccgatctcgcctggtttaaacgcaacaccttaaataaacccgtg
attatgggccgccatacctgggaatcaatcggtcgtccgttgccaggacgcaaaaatatt
atcctcagcagtcaaccgggtacggacgatcgcgtaacgtgggtgaagtcggtggatgaa
gccatcgcggcgtgtggtgacgtaccagaaatcatggtgattggcggcggtcgcgtttat
gaacagttcttgccaaaagcgcaaaaactgtatctgacgcatatcgacgcagaagtggaa
ggcgacacccatttcccggattacgagccggatgactgggaatcggtattcagcgaattc
cacgatgctgatgcgcagaactctcacagctattgctttgagattctggagcggcggtaa

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