Etheostoma spectabile (orangethroat darter): 116697664
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Entry
116697664 CDS
T08457
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1-like
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
esp
Etheostoma spectabile (orangethroat darter)
Pathway
esp00140
Steroid hormone biosynthesis
esp01100
Metabolic pathways
Module
esp_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
esp_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
esp_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
esp00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
116697664
Enzymes [BR:
esp01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
116697664
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
116697664
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GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
GDP_Man_Dehyd
NAD_binding_4
Polysacc_synt_2
NAD_binding_10
RmlD_sub_bind
NmrA
adh_short
KR
Motif
Other DBs
NCBI-GeneID:
116697664
NCBI-ProteinID:
XP_032384914
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Position
11:72398..77535
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AA seq
374 aa
AA seq
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MSLRGEVCVVTGAGGFLGKRLVRLLLEEEEMAEIRLLDKQIQPQLLDSLEDCRGNTKLSV
LEGDIRDGDFLRKSCRGASIVFHIASIIDVHGSVEDSELYSVNVKGTQLLLEACIQENVV
SFIYTSTIEVMGPNSNGEPIINGSEDTVYNCSLKFAYSKTKKEAEQRTLQAHSEVLNNGG
RLATCALRPMYIYGEGCRFLLGHMGDGIRNKGILFRMCQPEARVNPVYVGNVAIAHLQAA
RSLKDPQKRNAIGGKFYLISDDTPLLSYSDFSHVLMSPLGFSIQEKLMYPLRLLYMVCFL
MEMLCMMVRPFVRIVPPLNRQLVTMLNTPFSFSYEKAKRDLGYVPRYTWEEARKRTIEWL
ASELPKERERLIAK
NT seq
1125 nt
NT seq
+upstream
nt +downstream
nt
atgtctctgagaggggaagtgtgtgtggtgacgggagccggtggattcctgggaaagagg
ctggtgaggctgctgctggaggaagaggaaatggctgagattcgactgctggacaaacaa
atccagccacaacttctagactctctggaggactgtagaggcaacacaaagttgagtgtg
ttggagggggacatcagagacggggatttcctgagaaaaagctgccgaggtgcatcaatc
gtcttccacattgcatccatcattgacgttcatggctcagtggaggacagtgagctatac
agtgtcaatgtcaaaggaacgcagctgctcctggaggcttgtattcaagagaacgtggtg
tccttcatctacaccagtaccatcgaggtgatgggaccaaactctaacggtgaacccata
atcaacggcagcgaggacacagtttataactgctctctgaagtttgcctacagcaagacc
aagaaggaggctgagcagagaaccctgcaggcccacagcgaggtgctcaataacggaggc
cggctggcaacctgcgccctcagacctatgtacatctacggggagggctgccgcttcctg
ctgggccacatgggcgacgggatacgaaacaagggcattttgtttcgtatgtgtcaaccg
gaggcccgagtgaatcctgtgtatgtcggcaacgtggctatagcccacctccaagcagcc
cgcagcctcaaggatccacaaaaaagaaacgctatcggaggaaagttttacctaatttct
gatgacacgccacttctaagttattcggacttcagccacgtcctgatgtcccctctgggc
ttcagcattcaagagaagctcatgtacccgctccgcctcctctacatggtctgcttctta
atggagatgctgtgcatgatggtgcgacctttcgtacgcatcgtcccgcccctgaaccgg
cagctcgtcaccatgttgaacacgccgttcagcttctcgtatgagaaggctaagagggat
ctgggatacgtccccagatacacctgggaggaagcacgcaaacgcaccattgaatggctc
gcgtccgagctgccaaaggagagggaaagactaattgctaaataa
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