KEGG   Escherichia sp. E4742: FEM44_02115
Entry
FEM44_02115       CDS       T06276                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
esz  Escherichia sp. E4742
Pathway
esz03030  DNA replication
esz03410  Base excision repair
esz03420  Nucleotide excision repair
esz03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:esz00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    FEM44_02115 (ligA)
   03410 Base excision repair
    FEM44_02115 (ligA)
   03420 Nucleotide excision repair
    FEM44_02115 (ligA)
   03430 Mismatch repair
    FEM44_02115 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:esz03032]
    FEM44_02115 (ligA)
   03400 DNA repair and recombination proteins [BR:esz03400]
    FEM44_02115 (ligA)
Enzymes [BR:esz01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     FEM44_02115 (ligA)
DNA replication proteins [BR:esz03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     FEM44_02115 (ligA)
DNA repair and recombination proteins [BR:esz03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     FEM44_02115 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     FEM44_02115 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     FEM44_02115 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      FEM44_02115 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT HHH_5 Nlig-Ia DNA_ligase_ZBD PTCB-BRCT HHH RNA_ligase Prok-E2_C DZR_2 Zn_ribbon_NUD
Other DBs
NCBI-ProteinID: QCT86107
LinkDB
Position
complement(432242..434257)
AA seq 671 aa
MESIEQQLTELRTTLRHHEYLYHVMDAPEIPDAEYDRLMRELRELEAKHPELITPDSPTQ
RVGAAPLAAFSQIRHEVPMLSLDNVFDEESFLAFNKRVQDRLKSNEKVTWCCELKLDGLA
VSILYENGVLVSAATRGDGTTGEDITSNVRTIRAIPLKLQGENIPARLEVRGEVFLPQAG
FEKINEEARRTGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGVLEGGELPDTHL
GRLMQFKAWGLPVSDRVTLCESAEDVLAFYHKVEEDRPTLGFDIDGVVIKVNSLAQQEQL
GFVSRAPRWAVAFKFPAQEQMTFVRDVEFQVGRTGAITPVARLEPVHVAGVLVSNATLHN
ADEIERLGLRIGDKVVIRRAGDVIPQVVNVVLSERPEDTREVVFPTHCPVCGSDVERVEG
EAVARCTGGLICGAQRKESLKHFVSRRAMDVDGMGDKIIDQLVEKEYVHTPADLFKLTAG
KLTGLERMGPKSAQNVVNALEKAKETTFARFLYALGIREVGEATAAGLAAYFGTLEALES
ASIEELQKVPDVGIVVASHVHNFFAEESNRNVISELLAEGVHWPAPVVINAEEIDSPFAG
KTVVLTGSLSQMSRDDAKARLVELGAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGIEVI
DEAEMLRLLGN
NT seq 2016 nt   +upstreamnt  +downstreamnt
atggaatcaatcgaacaacaactgacagaactgcgaacgacgcttcgccaccatgaatat
ctttatcatgtgatggatgcgccggaaattcccgacgctgaatacgacaggctgatgcgc
gagttgcgtgagctggaagccaaacatcctgagctgattacccctgattcacctacccaa
cgtgtaggtgctgcgccgctggcagcctttagccagatccgtcatgaagtacccatgctg
tctctggataacgtatttgatgaagagagttttctcgccttcaacaaacgcgtacaggac
aggcttaaaagcaacgaaaaagtgacctggtgctgcgagttaaagctcgatgggcttgcc
gtcagcattctgtatgagaatggtgtactggtaagcgcggcgacccgtggcgatggcact
actggggaagacatcacgtctaacgtgcgtaccattcgcgctattccgctgaaactgcaa
ggtgagaatattccagcacgtctggaagtgcgtggtgaagtgttcctgccgcaggcgggt
tttgagaagattaacgaagaggcgcgacgcacgggcggaaaagtgtttgctaacccacgt
aatgcggcggcaggttctctgcgtcagcttgatccgcgtattactgcgaagcgaccgctt
actttcttctgctatggcgttggtgtactggaaggtggcgagttgccggacactcatctg
ggccgcttaatgcagtttaaagcgtggggattaccagtcagcgatcgggtaacgctttgc
gaatcagcagaagacgtgctggcgttttaccacaaagtggaagaagaccgcccgacgctg
ggctttgatattgacggtgtagtcattaaggtcaactcgctggcgcagcaggagcaactt
ggctttgtttcccgcgccccgcgctgggctgttgcgtttaaatttccggcgcaggaacaa
atgacttttgtgcgtgatgtagagtttcaggttgggcgtacaggtgcgattacgcccgtt
gcgcgtctggaacctgtccatgttgcaggcgtgctggtgagcaacgctacactgcataat
gccgacgaaattgaacgtctcggtttacgcattggcgataaagtggtgattcgccgcgca
ggagacgtgatcccacaagtggttaacgtcgtgctttctgaacgcccggaagatacccgt
gaggttgtattcccgacgcattgtccggtatgtggttctgacgtggaacgtgtggaaggt
gaagcggttgctcgctgtactggtggcctgatttgcggtgctcaacgtaaagaatcgctg
aaacactttgtttcccgtcgtgcgatggatgttgacggaatgggtgacaaaattatcgac
cagctggttgaaaaagagtacgtccacactccggcggacctgttcaaactcaccgcaggc
aaacttaccgggctggagcgaatggggccgaaatcggcacaaaatgtggttaacgcgctg
gaaaaagcgaaagaaaccacctttgcccgcttcctctatgcacttggcatccgtgaagtc
ggtgaggctaccgcagccggtctggcggcatattttggcacgctggaagcgctggaatca
gcctcgattgaagagctgcaaaaagtgccagacgtcgggatcgtggtggcatctcatgtt
cacaacttctttgccgaagaaagcaaccgcaatgtcatcagcgagctgttggcggaaggc
gttcactggcctgcgccggtcgtcatcaacgcagaagagatcgacagtccgtttgccggt
aaaaccgtggtactcacgggtagcttaagtcagatgtcgcgtgatgacgccaaagctcgc
ctggtcgaactgggcgcgaaagtggcgggcagcgtgtcgaagaaaaccgatctggtgatc
gccggagaagccgcaggttctaaactggcgaaagcgcaggaactgggcattgaagtgatc
gacgaagctgaaatgctacgtttgctgggtaactga

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