KEGG   Echinops telfairi (small Madagascar hedgehog): 101644287
Entry
101644287         CDS       T08707                                 
Symbol
HTRA2
Name
(RefSeq) serine protease HTRA2, mitochondrial isoform X1
  KO
K08669  HtrA serine peptidase 2 [EC:3.4.21.108]
Organism
etf  Echinops telfairi (small Madagascar hedgehog)
Pathway
etf04210  Apoptosis
etf04215  Apoptosis - multiple species
etf05012  Parkinson disease
etf05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:etf00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    101644287 (HTRA2)
   04215 Apoptosis - multiple species
    101644287 (HTRA2)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    101644287 (HTRA2)
   05022 Pathways of neurodegeneration - multiple diseases
    101644287 (HTRA2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:etf01002]
    101644287 (HTRA2)
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:etf03110]
    101644287 (HTRA2)
Enzymes [BR:etf01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.108  HtrA2 peptidase
     101644287 (HTRA2)
Peptidases and inhibitors [BR:etf01002]
 Serine peptidases
  Family S1: chymotrypsin family
   101644287 (HTRA2)
Chaperones and folding catalysts [BR:etf03110]
 Other chaperones and cochaperones
  DegP / HtrA
   101644287 (HTRA2)
SSDB
Motif
Pfam: Trypsin_2 Trypsin PDZ_6 PDZ_2 PDZ Peptidase_S46 GRASP55_65 PDZ_Tricorn
Other DBs
NCBI-GeneID: 101644287
NCBI-ProteinID: XP_004696170
UniProt: A0ABM0IB96
LinkDB
Position
Unknown
AA seq 452 aa
MAALRAGRGAGWSLPAWRALGGIRWGTGPLLTLDLRALLTSAASALQARKTCGTPSPRAR
LSAGVPDPRACLPPGTRAARAQWTAEIPGPGTREASGTRLRMWLAVALGAGGAVLLLWGG
GPPAVFAAVSGPPPYSPRSRYNFIADVVEKTAPAVVYIEILGRHPFSSREVPISNGSGFV
VAADGLIVTNAHVVANRRHVRVRLPSGDTYEAVVTAVDPVADIATLRIQTKEPLPTLPLG
RSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAAIDFGNS
GGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSWFGGSGSQRRYIGVMM
LTLTPSILAELQLREPSFPDVQHGVLIHKVILGSPAHRAGLRPGDVILAIGEQLVQNAED
VYEAVRTQSQLAVRIRRGPETLTLYVTPEVTE
NT seq 1359 nt   +upstreamnt  +downstreamnt
atggccgcgctgagggcggggcggggtgctggctggagcctcccagcatggcgggctttg
gggggcattcgctggggaacaggacccctgttgacccttgacctccgggctttgctgacg
tcagcagcttcggccctccaggcccggaagacgtgtgggacccccagtccccgggcccga
ctgtctgcaggggttcctgatccccgggcatgtctgccgccggggacccgggctgcccgg
gcacagtggaccgcggagatccccggtcccgggacccgggaggcctcggggacccgtctg
cgcatgtggctggcggtggcgctgggcgctgggggggctgtgctgctgctgtggggcggg
ggtcccccggcggtcttcgccgccgtctctggcccgccgccctactctccccggagccgg
tacaacttcattgcagacgtggtagagaagaccgcaccggccgtggtgtatatcgagatc
ctgggccgacaccctttctcgagccgcgaggtccccatctcaaatggctcaggattcgtg
gtggccgcggatggactgatcgtaaccaatgcccacgtggtggctaaccggcgccatgtc
cgtgtgaggctgcccagcggcgacacgtatgaagccgtggtcacagctgtggatcctgtg
gctgacatcgctaccctgaggattcagaccaaggaacctctccccacactgcctctggga
cgctcggccgacgttcggcaaggggagtttgttgttgccatgggaagtccctttgccttg
cagaacactatcacctccggcattgtcagctccgcccagcgcccagccagagacttggga
ttaccgcaaaccaacgtggaatacatccagactgatgccgctatcgattttgggaactct
ggaggccctctggttaacctggatggggaggtgatcggggtgaacaccatgaaggtcaca
gctggaatctccttcgccatcccatctgatcgccttcgggagtttctgcaccgtggggag
aagaagaattcctggtttggaggcagtgggtcccagcgccgatacattggggtgatgatg
ctgactctgactcccagcatccttgctgaactacagcttcgagaaccaagcttccctgat
gttcagcacggcgtgctcatccataaagtcatcctgggctcccctgcacaccgggctggt
ctgcggccgggtgacgtgatcttggctattggggagcagctggttcaaaatgccgaagac
gtctacgaagctgttcgaacccaatcccagctggctgtgcggatccggcgggggccagag
acactgaccttgtacgtgactcctgaagtcacagaatga

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