Echinops telfairi (small Madagascar hedgehog): 101646611
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Entry
101646611 CDS
T08707
Symbol
ROCK2
Name
(RefSeq) rho-associated protein kinase 2 isoform X1
KO
K17388
Rho-associated protein kinase 2 [EC:
2.7.11.1
]
Organism
etf
Echinops telfairi (small Madagascar hedgehog)
Pathway
etf04022
cGMP-PKG signaling pathway
etf04024
cAMP signaling pathway
etf04062
Chemokine signaling pathway
etf04071
Sphingolipid signaling pathway
etf04270
Vascular smooth muscle contraction
etf04310
Wnt signaling pathway
etf04360
Axon guidance
etf04510
Focal adhesion
etf04520
Adherens junction
etf04530
Tight junction
etf04611
Platelet activation
etf04670
Leukocyte transendothelial migration
etf04810
Regulation of actin cytoskeleton
etf04921
Oxytocin signaling pathway
etf05132
Salmonella infection
etf05135
Yersinia infection
etf05163
Human cytomegalovirus infection
etf05200
Pathways in cancer
etf05205
Proteoglycans in cancer
etf05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
etf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
101646611 (ROCK2)
04071 Sphingolipid signaling pathway
101646611 (ROCK2)
04024 cAMP signaling pathway
101646611 (ROCK2)
04022 cGMP-PKG signaling pathway
101646611 (ROCK2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
101646611 (ROCK2)
04520 Adherens junction
101646611 (ROCK2)
04530 Tight junction
101646611 (ROCK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
101646611 (ROCK2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
101646611 (ROCK2)
04670 Leukocyte transendothelial migration
101646611 (ROCK2)
04062 Chemokine signaling pathway
101646611 (ROCK2)
09152 Endocrine system
04921 Oxytocin signaling pathway
101646611 (ROCK2)
09153 Circulatory system
04270 Vascular smooth muscle contraction
101646611 (ROCK2)
09158 Development and regeneration
04360 Axon guidance
101646611 (ROCK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101646611 (ROCK2)
05205 Proteoglycans in cancer
101646611 (ROCK2)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
101646611 (ROCK2)
09171 Infectious disease: bacterial
05132 Salmonella infection
101646611 (ROCK2)
05135 Yersinia infection
101646611 (ROCK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101646611 (ROCK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
etf01001
]
101646611 (ROCK2)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
etf03036
]
101646611 (ROCK2)
Enzymes [BR:
etf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101646611 (ROCK2)
Protein kinases [BR:
etf01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
101646611 (ROCK2)
Chromosome and associated proteins [BR:
etf03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
101646611 (ROCK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH
C1_1
Pkinase_C
APH
Irp3-like_C
Motif
Other DBs
NCBI-GeneID:
101646611
NCBI-ProteinID:
XP_045142549
LinkDB
All DBs
Position
Unknown
AA seq
1390 aa
AA seq
DB search
MKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAF
ANSPWVVQLFCAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWAKFYTAEVVLALDAIH
SMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQG
GDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAK
NLICAFLMDREVRLGRNGVEEIKQHPFFKNDQWNWDNIRETAAPVVPELSSDIDSSNFDD
LEDDKGDVETFPIPKAFVGNQLPFVGFTYYRENLLLSDSPSCRENDLIQSRKNEESQEMQ
KKIDTLEEHLSNEIQAKEELEQKYKSANNRLEKITKELEEEVTLRKNGESSLRQLEREKA
LLQHRHAEHQRKADHAAEKKRNLENDVNSLKDQLEELKKRNQNSQMSTEKVNQLQRQLDE
TNALLRTESDTAVRLRKTQAESSKQIQQLESNNRDLQDKNCLLETAKLKLEKEFINLQSA
LESEKRDRTHGSEIINDLQGRISGLEEDLKNGKILLAKAEMEKRQLQERLTDLEKEKSNM
EIDMTYQLKVMQQTLEQEEAEHKTTKARLADKNKIYESIEEAKSEAMKEMEKKLLEERML
KQKVENLLLEAEKRCSIYDCDLKQSQQRVNELLKQKDVLNEDVRNLTLRIEQETQKRCLT
QNDLKMQTQQVNTLKMSEKQLKQENNHLLEMKMSLEKQNAELRKERQDADGQMKELQDQL
EAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKADSEQ
LARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLA
NEKEELNNKLKDAQEQLSRLKDEEISAAAIKAQFEKQLLSERTLKTQAVNKLAEIMNRKE
PVKRGSDTDVRRKEKENRKLHMELKSEREKLTHQMIKYQKELNEMQAQIAEESQIRIELQ
MTLDSKDSDIEQLRSQLQALHIGLDSSSIGSGPGDAEPDDGFPARITQSHTLESVSFTYQ
CASTSLSVASQPARARMRLDSESDSEEDSLPALPLSSEPNGTESRLEGWLSLPVRNNTKK
FGWVKKYVIVSSKKILFYDSEQDKEQSNPYMVLDIDKLFHVRPVTQTDVYRADAKEIPRI
FQILYANEGESKKEPEFPVEPAGEKSNYICHKGHEFIPTLYHFPTNCEACMKPLWHMFKP
PPALECRRCHMKCHKDHMDKKEEVIAPCKVYYDISTAKNLLLLASSTEEQQKWVSRLVKK
IPRKPPAPDPFARSSPRASMKAPPSQAARRPSRQLVPNKPRLLDLAFKDWDWSFDDVDDG
DDDDDDVFDF
NT seq
4173 nt
NT seq
+upstream
nt +downstream
nt
atgaaggcagaagactacgacgttgtgaaagtcattgggagaggtgcttttggtgaagtc
cagttggttcggcataaggcatcacagaaagtgtatgctatgaagcttcttagtaagttt
gaaatgatcaaaaggtcagattctgcttttttctgggaagaaagagatattatggccttt
gccaacagtccctgggtggttcagctcttttgtgccttccaagacgataggtatctgtac
atggtaatggagtacatgcctggcggagaccttgtcaaccttatgagtaactatgatgta
cccgaaaagtgggccaagttttacactgcagaagtagtcctcgctctggatgcaatacac
tccatgggcttaatacacagagatgtgaagccagacaacatgcttttggataaacatgga
cacctaaaattagcagattttggcacgtgtatgaagatggatgaaaccggcatggtgcac
tgtgacacagcagtcggaacaccggattacatatcacccgaggtgctcaagtctcaaggg
ggtgatggctactacgggcgagaatgtgattggtggtctgtaggggttttcctttttgag
atgctggtgggggatactccattttatgcagattcgcttgtaggaacatatagcaaaatc
atggatcataaaaactcactatgtttccctgaagatgcagaaatttctaaacatgcgaag
aatctcatctgtgccttcttaatggatagggaggtacggcttgggagaaacggtgtagag
gaaatcaaacagcaccctttctttaagaatgaccagtggaattgggataacatcagagaa
actgccgctcctgtagtccctgaactcagcagtgacatagacagcagcaattttgatgac
cttgaagatgataaaggagatgtggaaacatttccaattcctaaagcttttgtgggaaat
caactgccatttgtaggattcacctactatcgagaaaatttgttattaagcgactctcca
tcttgtagagaaaatgatttgatacaatcaaggaaaaatgaagaaagtcaagagatgcag
aaaaagatagacacgttagaagaacaccttagcaatgagattcaagccaaagaagagctg
gaacagaagtacaaatctgctaataaccgcctagagaaaatcacaaaggagctagaagaa
gaggtcaccttaaggaaaaatggggagtcgtcactaagacagctggagagagaaaaggct
cttctacagcacagacacgcagagcaccagcggaaagccgaccacgcagcggagaagaag
cgaaatctagaaaacgatgttaacagcttgaaagatcaacttgaagagttgaaaaaaaga
aatcaaaactcccaaatgtccacagagaaagtgaatcaactgcagagacaactggatgaa
acaaacgctttgctgaggacagaatctgacaccgctgtccgcttgaggaaaacccaggca
gaaagctccaaacagattcagcagttggaatctaataatcgagatctgcaggataaaaac
tgcctgttggagaccgccaaattaaaacttgagaaggagtttatcaatcttcagtcagcc
ctagaatctgaaaagagagatcgaacccatggatcagagataattaatgatttacaaggt
agaatatctggcttagaagaagacttaaagaatggcaaaattttattagcaaaagcagag
atggagaagaggcagctgcaggagagactcacagacttggaaaaggaaaaaagcaacatg
gaaatagacatgacgtaccaactgaaagtcatgcagcagaccctagaacaagaagaagcg
gagcataagactacaaaagcccggctagcagataaaaataagatctacgagtccattgaa
gaagcgaagtcggaagccatgaaagaaatggagaagaaactcctagaggaaaggatgtta
aagcagaaagtggagaacctgttgctggaggctgagaaaagatgttctatatacgattgt
gacctcaaacagtcacagcagagagtgaacgagctccttaaacagaaagatgtgctaaat
gaggatgttaggaacttgacgttgagaatagaacaggaaacgcagaagcgctgccttaca
cagaatgacctgaagatgcaaacacagcaggtgaacaccctgaaaatgtctgaaaagcag
ttgaagcaagagaacaaccaccttctggagatgaaaatgagcttggagaaacaaaatgct
gaacttcggaaagaacgccaggatgcagatgggcagatgaaggagctccaagaccagctt
gaagccgagcagtatttctcaacactctacaaaacacaggttagggaacttaaagaggaa
tgtgaagagaagaccaaacttggtaaagaattacagcagaagaaacaagaattacaggat
gagcgggactctttggctgcccagctggagatcaccttgaccaaagcagactctgaacag
ctggctcgttcgattgctgaagagcagtattctgacttggaaaaggagaaaatcatgaaa
gagctggagatcaaggagatgatggcccgacacaaacaggagctcacagaaaaagatgct
accattgcgtcgcttgaagaaactaataggacgctaaccagtgatgttgccaatcttgca
aatgagaaagaagaattgaacaacaaactgaaagatgctcaagagcagctatcaaggctg
aaagatgaagaaataagtgcagcggctattaaagcacagtttgagaagcagctgctgagt
gagagaacactgaagactcaagctgtgaataagttggctgagatcatgaaccggaaagag
cccgtcaagcgtggcagtgacaccgacgtgcggaggaaagagaaggagaaccggaagctg
cacatggagctgaagtccgaacgcgagaagctgacccaccagatgatcaagtaccagaag
gagctgaatgagatgcaggcccaaatcgccgaagagagccagattcgtatagaactgcag
atgaccctggacagtaaagacagtgacatcgagcagctgcggtcacagcttcaggccctg
cacattgggctcgatagttccagcatcggcagcgggccgggggatgccgagccagacgat
ggatttccagcccgtatcacccagtcacacactctggagtccgtgtccttcacctaccag
tgcgcctccacttccctcagtgtggcctcgcagcctgccagggcacgcatgcgccttgac
tcggagtctgactccgaagaagactccttgcccgccttaccgctgtcatcggagcctaat
ggtacagaatcgaggttagaagggtggctgtccttgcccgtgcgaaacaacaccaagaag
tttggatgggttaaaaagtatgtgattgtaagcagtaagaagatccttttttatgacagt
gaacaggataaagagcagtctaatccatacatggttttagatatagacaagttgtttcat
gtccgaccagtaacacagacagacgtatatcgagcagatgctaaagaaataccgaggata
ttccagattttgtatgccaacgaaggcgagagtaagaaggaaccggagtttccagtggaa
ccagcgggtgaaaaatcaaattatatttgccacaagggacatgagtttattcctactctc
tatcacttccccaccaactgtgaggcttgcatgaagcctctgtggcacatgtttaagccg
ccccctgctctggagtgccgtcgctgccacatgaagtgccacaaggaccacatggacaag
aaggaggaggtgatcgctccctgcaaagtatattacgatatttcaacggcgaagaacctg
ttgttgttagccagttccacagaagagcagcagaagtgggtgagtcggttggtgaaaaag
atccccagaaagcctccggccccagaccccttcgcccggtcgtcccccagggcttccatg
aaggccccgccgagccaggctgcccgacggccgagccgacagctggtcccaaacaagccc
agactgcttgatctggcgtttaaagactgggattggtcatttgatgatgttgatgatggt
gatgatgatgatgacgatgtttttgatttctga
DBGET
integrated database retrieval system
