KEGG Orthology (KO) [BR:etf00001]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
101650511
00670 One carbon pool by folate
101650511
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
101650511
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
101650511
Enzymes [BR:etf01000]
1. Oxidoreductases
1.5 Acting on the CH-NH group of donors
1.5.1 With NAD+ or NADP+ as acceptor
1.5.1.3 dihydrofolate reductase
101650511
152 aa
MASPLNCIIAVFQKLGISKNGNLPWPMLRNELQYFQSMTTTSPPSVEGKPKLVIVGRKPE
VSIPKNKSLKDRLNVVLSREPQEIPQGTHFLAKSLDGALKLIEQPELGSKADMVWIIGGS
SVYREAMDQPGHVSLFMTRIKQEFERHTFFFS