Escherichia coli O157 H7 TW14359 (EHEC): ECSP_3545
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Entry
ECSP_3545 CDS
T00949
Symbol
tyrA
Name
(GenBank) bifunctional chorismate mutase T/prephenate dehydrogenase
KO
K14187
chorismate mutase / prephenate dehydrogenase [EC:
5.4.99.5
1.3.1.12
]
Organism
etw
Escherichia coli O157:H7 TW14359 (EHEC)
Pathway
etw00400
Phenylalanine, tyrosine and tryptophan biosynthesis
etw00401
Novobiocin biosynthesis
etw01100
Metabolic pathways
etw01110
Biosynthesis of secondary metabolites
etw01230
Biosynthesis of amino acids
Module
etw_M00024
Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine
etw_M00025
Tyrosine biosynthesis, chorismate => HPP => tyrosine
Brite
KEGG Orthology (KO) [BR:
etw00001
]
09100 Metabolism
09105 Amino acid metabolism
00400 Phenylalanine, tyrosine and tryptophan biosynthesis
ECSP_3545 (tyrA)
09110 Biosynthesis of other secondary metabolites
00401 Novobiocin biosynthesis
ECSP_3545 (tyrA)
Enzymes [BR:
etw01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.12 prephenate dehydrogenase
ECSP_3545 (tyrA)
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.5 chorismate mutase
ECSP_3545 (tyrA)
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Motif
Pfam:
CM_2
PDH_C
PDH_N
F420_oxidored
Motif
Other DBs
NCBI-ProteinID:
ACT73307
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Position
complement(3518053..3519174)
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AA seq
373 aa
AA seq
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MVAELTALRDQIDEVDKALLNLLAKRLELVAEVGEVKSRFGLPIYVPEREASMLASRRAE
AEALGVPPDLIEDVLRRVMRESYSSENDKGFKTLCPALRPVVIVGGGGQMGRLFEKMLTL
SGYQVRILEQHDWDRAADIVADAGMVIVSVPIHVTEQVIGKLPPLPKDCILVDLASVKNG
PLQAMLAAHDGPVLGLHPMFGPDSGSLAKQVVVWCDGRKPEAYQWFLEQIQVWGARLHRI
SAVEHDQNMAFIQALRHFATFAYGLHLAEENVQLEQLLALSSPIYRLELAMVGRLFAQDP
QLYADIIMSSERNLALIKRYYKRFGEAIELLEQGDKQAFIDSFRKVEHWFGDYAQRFQSE
SRVLLRQANDNRQ
NT seq
1122 nt
NT seq
+upstream
nt +downstream
nt
atggttgctgaattgaccgcattacgcgatcaaattgatgaagtcgataaagcgctgctg
aatttattagcgaagcgtctggaactggttgctgaagtgggcgaggtgaaaagccgcttt
ggactgcctatttatgttccggagcgagaggcatctatgttggcctcgcgtcgtgcagag
gcggaagctctgggtgtaccgccagatctgattgaggatgttttgcgtcgggtgatgcgt
gaatcttactccagtgaaaacgacaaaggatttaaaacgctttgtcctgcgttacgcccg
gtagttatcgttggcggcggcggtcagatgggacgtctgttcgagaagatgctgacactc
tcgggttatcaggtgcggattctggagcaacatgactgggatcgagcggctgatattgtt
gccgatgccggaatggtgattgttagtgtgccaatccacgttactgagcaagttattggc
aaattaccgcctttaccgaaagattgtattctggttgatctggcatcagtgaaaaatgga
ccattacaggccatgctggcggcgcacgatggcccggtactggggttacacccaatgttc
ggtccggacagcggtagcctggcaaagcaagttgtggtctggtgtgatggacgtaaaccg
gaagcataccaatggtttctggagcaaattcaggtctggggcgctcggttgcatcgtatt
agcgccgtcgagcacgatcagaatatggcgtttattcaggcactgcgccactttgctact
tttgcttacgggctgcacctggcagaagaaaatgttcagcttgagcaacttctggcgctc
tcttcgccgatttaccgccttgagctggcgatggtcgggcgactgttcgctcaggatccg
cagctttatgccgacattattatgtcgtcagagcgtaatctggcgttaatcaaacgttac
tataagcgtttcggcgaggcgattgagttgctggagcagggcgataagcaggcgtttatt
gacagtttccgcaaggtggagcactggttcggcgattacgcacagcgttttcagagtgaa
agccgcgtgttattgcgtcaggcgaatgacaatcgccagtaa
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