Frankia alni: FRAAL0172
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Entry
FRAAL0172 CDS
T00384
Symbol
metH
Name
(GenBank) B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
fal
Frankia alni
Pathway
fal00270
Cysteine and methionine metabolism
fal00450
Selenocompound metabolism
fal00670
One carbon pool by folate
fal01100
Metabolic pathways
fal01110
Biosynthesis of secondary metabolites
fal01230
Biosynthesis of amino acids
fal04980
Cobalamin transport and metabolism
fal04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
fal00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
FRAAL0172 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
FRAAL0172 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
FRAAL0172 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
FRAAL0172 (metH)
04980 Cobalamin transport and metabolism
FRAAL0172 (metH)
Enzymes [BR:
fal01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
FRAAL0172 (metH)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
CAJ58851
UniProt:
Q0RU92
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Position
complement(167874..171476)
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AA seq
1200 aa
AA seq
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MVVLDGAWGTMLQNAGLTPADYQLDSLRDHPKDVTGDPDLLNLTRPDIILDVHRQYLAAG
ADITTTNTFTATSIGQADYGLESLVREMNLRGAQLARQAADEAGGRFVAGSIGPLNVTLS
LSPRVEDPAYRAVTFDQVRAAYAEQIQALADGGVDLLLIETIFDTLNAKAAIAAAREVAP
QLPLWISVTIVDLSGRTLSGQTVEAFWDSIAHANPLVVGVNCSLGAEEMRPHVEALARIA
GTYTACHPNAGLPNAFGGYDQTPEEAGRLIGEFAAAGMVNIVGGCCGTTPAHIARIAAAV
DGTAPRQVPTPTPRTRFSGLEPFEIGEDTGFVMIGERTNVTGSARFRRLVEADDYQAAVD
VALEQVRGGANLLDVNMDADLLDSEQAMTTFLNLLATEPEAARLPIMIDSSRWSVLEAGL
RCVQGKGVVNSISLKEGEEVFLDHARRIRDFGAGVVVMAFDEQGQADTTERKVAICGRAY
DLLTGKLGFPATDIIFDPNVLAVATGIPEHNGYAKAFIDALPLIKQRCPGVRISGGISNL
SFSFRGNDVVREAMHSAFLLHAVRAGLDMGIVNAGQLAVYADIPAELLELVEDVLFDRRE
DATDRLVAFAETVSGKGTQRVVDLSWREAPVAARLSHALVHGIVDFIEADTEEARAAAAR
PLDVIEGPLMDGMKIVGDLFGSGKMFLPQVVKSARVMKRSVAYLEPFMEAEKAQAALDDS
AAGRPAARRGNGKVVLATVKGDVHDIGKNIVGVVLGCNNYEVIDLGVMVPAKVILDTAVA
EGADAVGLSGLITPSLDEMVAVGAEMQRRGLRLPLLIGGATTSRQHTAVRIAPVYEATTV
HVLDASRVVGVVSDLLDAERAEQLDVRNRAEQARLREQHENRRAQPLLGLEQARANREQV
SFDELPVPAFTGRRIVTPDLTALREMIDWQFFFLAWELKGKFPAILDEPVARELFDEANV
LLDQIIKDGSLQAKGVYGFWPAFADGDDLVIEAGEVAGARDGVLRLPMLRQQTTKPTGRP
NRSLADYVAPAGDHLGGFAVAVHGADTLAAEFEARQDDYRSIMVKALADRLAEAFAEYIH
LAARREWFEPDAEPSLADLHAERFRGIRPALGYPASPDHSEKQALFDLLDAGQAGLGLTE
SFAMTPASAVSGIIFAHPESKYFTVGRIGRDQVEDYARRRGLGVGDVERWLRPNLAYDPA
NT seq
3603 nt
NT seq
+upstream
nt +downstream
nt
gtggtcgttctggacggcgcctggggcacgatgctgcagaatgccggcctcaccccggcg
gactaccagctcgactcgctgcgtgaccatcccaaggacgtgaccggcgacccggacctg
ctgaacctgacccggccggacatcatcctcgacgtgcaccggcagtacctggcggcgggc
gcggacatcaccaccacgaacaccttcaccgcgacgagcatcggccaggccgactacggc
ctggagtcgctggtgcgggagatgaacctgcgcggggcgcagctggcccggcaggccgcg
gacgaggcgggcgggcggttcgtcgccggctccatcggcccactcaacgtcaccctgtcg
ctgtccccgcgggtggaggacccggcgtaccgggcggtgaccttcgaccaggtccgcgcc
gcctacgccgagcagatccaggccctcgccgacggcggggtggacctgctgctcatcgag
acgatcttcgacacgctgaacgcgaaggccgcgatcgccgcggcccgcgaggtcgcgccg
cagctgccgctgtggatctcggtgacgatcgtcgacctgtccgggcggaccctgtcgggg
cagacggtcgaggcgttctgggactccatcgcccacgcgaacccgctggtcgtcggcgtg
aactgctcgctgggcgccgaggagatgcgcccccacgtcgaggcgctggcccgcatcgcc
ggcacctacaccgcctgccacccgaacgccgggctgcccaacgccttcggcggctacgac
cagacgccggaggaggccggccggctgatcggcgagttcgccgccgccggcatggtcaac
atcgtcggcggctgctgcgggacgacgccggcgcacatcgcccggatcgccgccgccgtc
gacgggaccgcgccccgccaggtgcccacgccgacgccgcggaccaggttcagcggcctg
gaaccgttcgagatcggcgaggacaccggcttcgtcatgatcggcgaacggaccaacgtc
accggctcggcgcggttccgccgcctcgtcgaggccgacgactaccaggccgccgtcgac
gtcgccctggagcaggtccgcggcggggcgaacctgctcgacgtcaacatggacgccgac
ctgctcgacagcgagcaggcgatgacgacgttcctgaacctgctggccaccgagccggag
gccgcccgcctgccgatcatgatcgacagttcgcggtggagcgtgctggaggccgggctg
cgctgcgtgcagggcaagggcgtggtcaactcgatcagcctcaaggagggcgaggaggtc
ttcctcgaccacgcccggcgcatccgcgacttcggcgccggcgtcgtcgtcatggccttc
gacgagcagggccaggcggacaccaccgagcgcaaggtggcgatctgcgggcgtgcctac
gacctgctcaccggcaagcttggtttcccggccacggacatcatcttcgacccgaacgta
ctcgccgtggccaccggcattcccgagcacaacggctacgccaaggcgttcatcgacgcc
cttccgctgatcaagcagcgctgcccgggggtgcggatcagcggcgggatctcgaacctg
tcgttctccttccgcggcaacgacgtcgtccgcgaggcgatgcactcggcgttcctgctg
cacgcggtgcgcgccgggctcgacatgggcatcgtgaacgccggccagctcgccgtctac
gccgacatccccgccgagctgctcgaactcgtcgaggacgtgctgttcgaccggcgcgag
gacgccaccgaccggctcgtcgccttcgccgagacggtcagtggcaagggcacgcagcgg
gtcgtcgacctgtcctggcgcgaggcgccggtcgcggcgcggctctcgcacgcgctcgtg
cacggcatcgtcgacttcatcgaggccgacacggaggaggcgcgggccgccgcggcgcgc
cccctcgacgtgatcgagggcccgctgatggacggcatgaagatcgtcggcgacctgttc
ggttcggggaagatgttcctgccgcaggtcgtgaagagcgcgcgggtgatgaagcggtcg
gtggcctacctggagccgttcatggaggccgagaaggcgcaggccgccctcgacgacagc
gccgcgggccggccggctgcccggcgcggcaacgggaaggttgtgctcgccaccgtcaag
ggcgacgtccacgacatcggcaagaacatcgtcggcgtcgtgctcggctgcaacaactac
gaggtcatcgacctcggcgtgatggtccccgccaaggtcatcctcgacaccgccgtcgcc
gagggggcggacgcggtcggcctgtccggcctgatcacgccgtcgctggacgagatggtc
gcggtcggcgccgagatgcagcgccgcgggctgaggctgccgctgctcatcggcggcgcc
accacctcccgccagcacaccgcggtgcgcatcgccccggtctacgaggccaccaccgtc
cacgtgctcgacgcctcccgcgtcgtcggggtggtctcggacctgctcgacgccgagcgg
gccgagcagctcgacgtgcgcaaccgggccgagcaggcgcggctgcgcgagcagcacgag
aaccgccgggcgcagccgctgctcggtctggagcaggcgcgggccaaccgcgagcaggtg
tccttcgacgagctgcccgtccccgccttcaccggacgccgcatcgtcacgccggacctc
accgcgctgcgcgagatgatcgactggcagttcttcttcctcgcctgggagctgaagggc
aagttccccgcgatcctcgacgagccggtcgcccgcgagctgttcgacgaggcgaacgtg
ctgctcgaccagatcatcaaggatggcagcctgcaggcgaagggcgtctacggcttctgg
cccgccttcgccgacggcgacgacctggtgatcgaggccggcgaggtggcgggcgcccgc
gacggggtgctgcggctgccgatgctgcgccagcagacgacgaagcccaccggccggccc
aaccgcagcctcgccgactacgtcgcgcccgccggtgaccacctcggcggcttcgccgtg
gccgtccacggcgcggacacgctcgccgccgagttcgaggcgcgccaggacgactaccgg
tcgatcatggtgaaggcgctcgcggaccggctcgcggaggcgttcgccgagtacatccac
ctggccgcgcgccgcgagtggttcgaaccggacgccgagccgagcctcgcggacctgcac
gcggagcgcttccgtggcatccgcccggcgctcggctacccggccagccccgaccacagc
gagaagcaggcgctgttcgacctgctcgacgccggccaggccggcctgggcctgaccgag
tcgttcgcgatgaccccggcgtcggccgtcagcgggatcatcttcgcccatcccgagtcg
aagtacttcaccgtggggcgcatcggccgggaccaggtcgaggactacgcccgccggcgc
ggactcggcgtcggcgacgtcgagcgctggctgcgccccaacctcgcctacgaccccgcc
taa
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