Felis catus (domestic cat): 100142684 Help Entry 100142684         CDS       T02385                                  Symbol CASP8 Name (RefSeq) caspase-8   KO K04398   caspase 8 [EC:3.4.22.61] Organism fca  Felis catus (domestic cat) Pathway fca01524   Platinum drug resistance fca04115   p53 signaling pathway fca04210   Apoptosis fca04215   Apoptosis - multiple species fca04217   Necroptosis fca04620   Toll-like receptor signaling pathway fca04621   NOD-like receptor signaling pathway fca04622   RIG-I-like receptor signaling pathway fca04623   Cytosolic DNA-sensing pathway fca04625   C-type lectin receptor signaling pathway fca04657   IL-17 signaling pathway fca04668   TNF signaling pathway fca04932   Non-alcoholic fatty liver disease fca04936   Alcoholic liver disease fca05010   Alzheimer disease fca05016   Huntington disease fca05022   Pathways of neurodegeneration - multiple diseases fca05132   Salmonella infection fca05134   Legionellosis fca05142   Chagas disease fca05145   Toxoplasmosis fca05152   Tuberculosis fca05160   Hepatitis C fca05161   Hepatitis B fca05162   Measles fca05163   Human cytomegalovirus infection fca05164   Influenza A fca05165   Human papillomavirus infection fca05167   Kaposi sarcoma-associated herpesvirus infection fca05168   Herpes simplex virus 1 infection fca05169   Epstein-Barr virus infection fca05170   Human immunodeficiency virus 1 infection fca05200   Pathways in cancer fca05203   Viral carcinogenesis fca05416   Viral myocarditis fca05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:fca00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     100142684 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     100142684 (CASP8)    04215 Apoptosis - multiple species     100142684 (CASP8)    04217 Necroptosis     100142684 (CASP8)    04115 p53 signaling pathway     100142684 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     100142684 (CASP8)    04621 NOD-like receptor signaling pathway     100142684 (CASP8)    04622 RIG-I-like receptor signaling pathway     100142684 (CASP8)    04623 Cytosolic DNA-sensing pathway     100142684 (CASP8)    04625 C-type lectin receptor signaling pathway     100142684 (CASP8)    04657 IL-17 signaling pathway     100142684 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100142684 (CASP8)    05203 Viral carcinogenesis     100142684 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     100142684 (CASP8)    05161 Hepatitis B     100142684 (CASP8)    05160 Hepatitis C     100142684 (CASP8)    05164 Influenza A     100142684 (CASP8)    05162 Measles     100142684 (CASP8)    05168 Herpes simplex virus 1 infection     100142684 (CASP8)    05163 Human cytomegalovirus infection     100142684 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     100142684 (CASP8)    05169 Epstein-Barr virus infection     100142684 (CASP8)    05165 Human papillomavirus infection     100142684 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     100142684 (CASP8)    05134 Legionellosis     100142684 (CASP8)    05152 Tuberculosis     100142684 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     100142684 (CASP8)    05142 Chagas disease     100142684 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     100142684 (CASP8)    05016 Huntington disease     100142684 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     100142684 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     100142684 (CASP8)    05416 Viral myocarditis     100142684 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     100142684 (CASP8)    04932 Non-alcoholic fatty liver disease     100142684 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     100142684 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:fca01002]     100142684 (CASP8) Enzymes [BR:fca01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      100142684 (CASP8) Peptidases and inhibitors [BR:fca01002]  Cysteine peptidases   Family C14: caspase family    100142684 (CASP8) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C14 DED PYRIN Motif Other DBs NCBI-GeneID:  100142684 NCBI-ProteinID:  XP_006935535 UniProt:  A0A5F5XMX6 LinkDB All DBs Position C1:187151489..187176938 Genome browser AA seq 479 aa AA seqDB search MDFSKCLYNIGEQLGSDELASLKFLSLDYIPQKKQEPIKDALMLFQRLQEKRMLEESNLS FLKELLFRINRLDLLFNYLNTSKEAMEQELQIPGRAQIPPYRVMLFQISEDVNKLELRSF KFLLSQEISRCKVDDDMNLLDIFIEMEKRVILGERNLDTLKRICDQINKSLLKKITDYEE LSREGRTSLQRSPDELSNGEESLAMMALSDSLEEQDSESQTSDKVYRMKSKPRGYCLIFN NYDFSRARKDVPKLQNIKDRNGTNFDAEALSKTFSELHFEIVNFKDSTAKTICEVLKSYQ RMDHNNKDCFICCILSHGDKGIIYGSDGQEAPIYELTSYFTGSKCPSLAGKPKIFFIQAC QGDNYQRGIAVETDSEQKEDYLEMDSSFQKRYIPDEADFLLGMATVNNCVSYRNPTEGTW YIQSLCQSLRERCPRGEDILTILTEVNFEVSNKDDKKNMGKQMPQPTFTLRKKLFFPLN NT seq 1440 nt NT seq  +upstreamnt  +downstreamnt atggatttcagtaaatgtctgtataatattggggaacagctgggcagtgacgagctggcc tccctcaaattcctgagcctggactacatcccacaaaagaagcaagaacccatcaaagat gccttgatgttattccagagactccaggaaaagagaatgttggaggaaagcaacttgtcc ttcttgaaggagctgcttttccgaattaatagactggacctgctgttcaactacctgaac accagcaaggaagcgatggagcaggagcttcagataccaggcagagcccagatccctccc tacagggtcatgctttttcagatttcagaagatgtaaacaaattggaattgaggtcgttt aagtttcttttgagccaggagatctccagatgtaaagtggatgatgatatgaacttgctt gatattttcatagagatggaaaagagggtcatcctaggggaaagaaatttggacactctg aaaagaatctgtgaccaaatcaacaagagcctgctgaagaaaatcactgattatgaagaa ttaagcagagagggaagaacgagccttcaaagaagtccagatgaattgtcaaatggggag gaatccctggcaatgatggcattatcggactctctagaagaacaggacagtgagtcacag acatcggacaaagtttaccgaatgaaaagcaaacctcgcggatattgtttgatctttaac aattatgattttagcagagcacggaaggatgtgcccaaacttcagaacattaaggatagg aatggaacaaacttcgatgcagaagctttgagtaagacctttagtgagcttcattttgag attgtgaatttcaaagactctacagcaaagacaatctgtgaagttctgaaatcctaccaa agaatggaccataataacaaagattgcttcatctgctgtatcctctcccatggagacaaa ggcattatttatggctctgatgggcaggaagcccccatctatgagctgacttcttacttc actggttcaaagtgcccttcccttgcaggcaagcccaaaatcttttttattcaggcttgt caaggggataactaccagagaggtatagctgttgagactgactccgaacagaaggaagac tacttagaaatggactcatcatttcagaagagatatatcccagatgaggctgattttctg ctggggatggccactgtgaacaactgtgtttcctaccgaaaccctacggaggggacctgg tatatccagtcactttgccagagcctaagagaaagatgtcctaggggtgaagatatcctc accatccttactgaggtgaactttgaagtgagcaataaggatgacaagaaaaacatgggg aaacaaatgccacaacctactttcacactgaggaaaaaactcttcttccctcttaattga

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