Felis catus (domestic cat): 100270775 Help Entry 100270775         CDS       T02385                                  Symbol FASN Name (RefSeq) fatty acid synthase isoform X1   KO K00665   fatty acid synthase, animal type [EC:2.3.1.85] Organism fca  Felis catus (domestic cat) Pathway fca00061   Fatty acid biosynthesis fca01100   Metabolic pathways fca01212   Fatty acid metabolism fca04152   AMPK signaling pathway fca04910   Insulin signaling pathway fca04936   Alcoholic liver disease Module fca_M00082   Fatty acid biosynthesis, initiation fca_M00083   Fatty acid biosynthesis, elongation Brite KEGG Orthology (KO) [BR:fca00001]  09100 Metabolism   09103 Lipid metabolism    00061 Fatty acid biosynthesis     100270775 (FASN)  09130 Environmental Information Processing   09132 Signal transduction    04152 AMPK signaling pathway     100270775 (FASN)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     100270775 (FASN)  09160 Human Diseases   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     100270775 (FASN)  09180 Brite Hierarchies   09181 Protein families: metabolism    01004 Lipid biosynthesis proteins [BR:fca01004]     100270775 (FASN)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:fca04147]     100270775 (FASN) Enzymes [BR:fca01000]  2. Transferases   2.3  Acyltransferases    2.3.1  Transferring groups other than aminoacyl groups     2.3.1.85  fatty-acid synthase system      100270775 (FASN) Lipid biosynthesis proteins [BR:fca01004]  Fatty acid synthase   Animal type    100270775 (FASN) Exosome [BR:fca04147]  Exosomal proteins   Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)    100270775 (FASN)   Exosomal proteins of breast milk    100270775 (FASN)   Exosomal proteins of colorectal cancer cells    100270775 (FASN)   Exosomal proteins of bladder cancer cells    100270775 (FASN) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Acyl_transf_1 ketoacyl-synt Thioesterase KR Ketoacyl-synt_C KAsynt_C_assoc FAS_pseudo-KR ADH_zinc_N_2 ADH_zinc_N PKS_DH_N PP-binding Methyltransf_12 adh_short PS-DH Methyltransf_23 Methyltransf_11 Thiolase_N ACP_SdgA_C Methyltransf_31 Methyltransf_25 AlaDh_PNT_C Motif Other DBs NCBI-GeneID:  100270775 NCBI-ProteinID:  XP_023100132 LinkDB All DBs Position E1:complement(60835091..60853490) Genome browser AA seq 2515 aa AA seqDB search MEEVVIAGMSGKLPESENMEEFWANLIGGVDMVTDDDRRWKAGLYGLPKRTGKLKDLSKF DASFFGVHPKQAHTMDPQLRLLLEVTYEAILDGGINPATLRGTHTGVWVGVSGSEASEAL SRDPETLVGYSMVGCQRAMMANRLSFFFDFKGPSIALDTACSSSLLALQNAYQAIRRGEC PAAIVGGLNLLLKPNTSVQFMKLGMLSPDGICKAFDESGDGYCRAEAVVAVLLTKKSLAR RVYATILNAGTNTDGCKEQGVTFPSGEVQEQLIRSLYEPAGLSPESLEYIEAHGTGTKVG DPQELNGIARALCPSRQEPLLIGSTKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFR SPNTKIPALQDGRLQVVQQPLPVRGGNVCINSFGFGGSNVHVILRPNMRPPLAPTRHASL PRLLRASGRTPEAVHCLLEQGRRHSQDLAFVSMLNDIAAISPTAMPFRGYTVLGGKGGSQ EVQLVAAGKRPLWFICSGMGAQWCGMGLSLMRLGSFRDSILRSDEAVKPLGLQVSELLLS TDEATFDDIIHAFVSLTAIQIALIDLLNSMGLRPDGIIGHSLGEVACGYADGCLSQEEAI LAAYWRGQCIKETNIPPGTMAAVGLSWEECKQRCPPGVVPACHNSEDTVTISGPQAEVAA FVAELKREGVFAKEVRTGGMAFHSYFMDSIAPTLLQALKKVIREPRPRSARWLSTSIPEA QWQGSLARTFSAEYNVNNLVSPVLFQEALWHVPGDAVVLEIAPHALLQAVLKRGLKSSCT IVPLMKKDQRDNLEFFLSNVGKLHLLGFDVNPNGLLPPVEFPVPRGTPLISPHIKWDHSQ TWDVPTAKDFPSGSSGSSASTVCNISISPESPDHYLADHCIDGRVLFPATGYLCLVWKTL ARTLSQNMEQVPVVFEDVTLHQATVLPKTGTVPLEVRLLQASRTFEVSENGNLIVSGKVY QWEDPDTKLFDSRDGLDATDPMATFHLSQRDVYKELRLRGYDYGPHFQGILEANLEGNAG RLLWKNNWVTFLDAMLQTSILGLAQRGLRLPTRITSVRIDPATHQRRVYSLQGEAQAVNV LVNRCLNSTVAGGVLVSGLHASMAPRRQQEQFAPILEKFCFTPHTEEGLLAGDAALQEGL QLCRGLAQALQTKVAQQGLKMVVSGLDGAQAPQEPPKQGLPRLLAAACQLQLNGGLQLEL GQLLAQQRPLLQDDPLLSGLLASPALKACVDTALENMPSLKMKVVEVLAGDGRLYSHIPA LLNTQPMLQLEYTATDRHPQALEAVQAKLQQHGIAQGQWDPADHAPGSLGSADLLLCNCA VASLSDPAVAVGNMGAALKEGGFLLLHALLKGHPLGETVAFLTCPEPQRGQQSLLSQDQW ESLFAGASLHLVALKKSFYGSVLFLCRRPVLWDSPVFLPVEDPSFQWVNSLKNILADSSQ QPVWLTATSCPDSGIVGLVNCLRREPGGHRIRCVLVSNLSSTSSTPSLDPGSSELQKVLR GDLVMNVYRDGAWGAFRHFPLERGLPEEQTEHAFVNVLTRGDLSSIRWVCSPLRHTQLTG PGTHLCAVYYASLNFRDIMLATGKLSPDAIPGKWARHDCLLGMEFSGRDASGKRVMGLVP AEGLATSVLLSQDFLWEVPSSWTLEEAASVPVVYTTAYYSLVVRGRVQPGETVLIHSGSG GVGQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDDTSFANSRDTSFEQHVLRHTAG KGVDLVLNSLAEEKLQASVRCLAQHGRFLEIGKFDLSNNHLLGMAVFLKNVTFHGVLLDS LMDEGGNSWQEVAALLKAGIRDGVVQPLKCTVFPKDRVEDAFRYMAQGKHIGKVVVQVRR EEPEAVLRETGPTLMAAVSKTYCPAHKSYVITGGLGGLGLELAQWLVLRGARKLVLTSRS GIRTGYQAKQVREWRRQGIQVLVSTSNASSLDGAQSLIDEATQLGPVGGVFNLAVVLRDA MLENQTPELFEDVVRPKYSGTVNLDRVTRAACPELDYFVAFSSVSCGRGNAGQTNYGFAN STMERVCEKRQHDGLPGLAIQWGAVGDVGIVLESMGSNDVVIGGTLPQRIASCLEVLDVF LNQPHPVLSSFVLAEKKATAHNDSSSRQDPMEAVAHILGIRDLATVNLDSSLADLGLDSL MGVEVRQMLEREHDLVMSMRDIRQLTLRKLQELSSKAGTANELAAPTPKEDTPAGQQAQL NLSTLLVNPEGPTLTRLNSVQSSERPLFLVHPIEGSITVFRSLASKLSIPTYGLQCTRAA PLDSIQSLAAYYIECIRQVQPEGPYRIAGYSYGACVAFEMCSQLQAAQQGPTPAHNSLFL FDGSHTYVLAYTQSYRAKLTPGCEAEAEAEAMCFFVQQFTDMEHNRVLEALLPLKGLEER VAATVDLITRSHAGLDPRELSFAARSFYHKLRAAEQYIPRDTYHGNVTLLRTKTGSVYGE GLGADYNLSQVCDGKVSVHVIEGDHRTLLEGSGLETILSIIHSSLAEPRVSVREG NT seq 7548 nt NT seq  +upstreamnt  +downstreamnt atggaggaagttgtgattgctggcatgtccgggaagctgcccgagtcggagaacatggag gagttctgggccaacctcatcggcggcgtggacatggtgacagacgatgacaggaggtgg aaggcaggactctacggcctgcccaagcgtaccggcaagctaaaggacctgtccaagttc gatgcctccttcttcggggtccacccaaagcaggctcacacgatggacccccagctgcgc ttgctcctggaagtcacctacgaggccatcctggatggaggcatcaacccggctaccctg cgagggacacacacaggcgtctgggtgggcgtgagcggctcggaggcctcagaggctctg agccgagaccccgagactctcgtgggctacagcatggtgggctgccagcgggctatgatg gccaaccgcctctccttcttctttgattttaaagggcccagcatcgctctggacacggcc tgctcctccagcctgctggcccttcagaacgcctaccaggccatccgcaggggagagtgc cccgcggccatcgtgggcggcctcaacctcctgctcaagcccaacacctccgtgcagttc atgaagctcggcatgctgagccccgacggaatctgcaaggccttcgacgagtccggggac ggctactgccgtgcggaggccgtggtggccgtcctgctgaccaagaagtccctggcccgg cgtgtgtatgccaccatcctcaatgcaggcaccaacacggatggctgcaaggagcaaggt gtgacctttccctccggggaagtacaagaacagctcatccgctcgctgtacgagccggct gggttgagcccagagtccctcgagtatatcgaagcccacggcacagggaccaaggtgggg gacccccaggagctgaacggcattgcccgagccctgtgtccctcccgccaggagcccctg ctgatcgggtccaccaagtcgaacatggggcacccggagcccgcttcggggctcgcggct ctggccaaggtgctgctgtccctggagcatgggctctgggcccccaacctgcacttccgg agcccgaacaccaagatccccgcgctccaggatggacggctgcaggtggtgcagcagccc ctgcccgtccgcggaggcaacgtgtgtatcaattcgttcggcttcggcggctccaacgtg cacgtcattctccggcccaatatgcggccgcccttggcacccacccggcacgcctctctg ccccgtctgctgcgggccagcggacgcaccccggaggccgtgcactgcctgctggagcaa ggccgccggcacagccaggacctggccttcgtgagcatgctcaatgacatcgcggccatc tcccccaccgccatgcccttccggggctacaccgtgctgggtggcaagggcggcagccag gaggtacagctggtggccgctggcaagcgtccgctctggttcatctgctcggggatgggc gcacagtggtgcgggatgggattgagcctcatgcgcctgggcagcttccgggactccatc ctgcgctccgacgaggccgtgaagcccttgggactgcaggtgtctgagttgctgctgagc acagacgaggccacctttgacgacatcatccacgccttcgtgagcctcaccgccatccag atcgccctcatagacctgctgaactccatgggtctgcggcccgacggaatcatcgggcac tccctgggtgaggtggcctgtggctacgcagatggctgcctttctcaggaggaggccatc ctcgccgcctactggaggggccagtgcatcaaggagaccaacatcccaccggggaccatg gcggccgtcggcctgtcctgggaggagtgtaagcagcgctgcccccctggtgtcgtgccc gcctgccacaactctgaggacacagtgaccatctcgggaccgcaggctgaggtggctgcg ttcgtggcggagctgaagcgggagggtgtgtttgccaaggaggtgcggacgggcggcatg gccttccactcctacttcatggactccatcgcccccacgttgcttcaggccctcaagaag gtgatccgggagccgcggccccgctcggcacgctggctcagtacttccatccccgaggcc cagtggcagggcagcctggcccgcacgttctcggcggagtataacgtcaacaatctggtg agccccgtgctgttccaggaggcgctgtggcatgtgcccggggacgccgtggtgttggag atcgccccccatgcgctgctgcaggccgtccttaagagaggcctgaagtccagctgtacc atcgtccctctgatgaagaaggaccaaagagacaacctggagttcttcctcagcaacgtg ggcaagttgcacctgctgggcttcgatgtcaaccccaatggcctgcttccacccgtggag ttcccggtgccccggggcactcctctcatctcccctcacatcaagtgggaccacagtcag acctgggacgtccccaccgccaaggacttccccagcggctccagtggctcctctgcctcc accgtctgcaacatcagcatcagccctgaatcccctgaccactacctggcggaccactgc atcgacggccgcgtcctcttccccgccaccggctacctgtgcctggtctggaagactctg gcacggaccttgagtcaaaacatggaacaagtacccgtggtgtttgaggacgtgacactg caccaggctaccgtcctacccaagaccgggaccgtgcccctggaagtgcggctcctacag gcttcccgcaccttcgaggtgtctgagaacggcaacctgatagtgagcgggaaggtttac cagtgggaggaccccgacaccaagctgttcgacagccgggacggcctggacgccacggac cccatggctacgttccacctgagccagagggacgtgtacaaagagttgaggctgcgtggc tatgactacggccctcactttcaaggcatcctcgaggccaacctcgaaggcaacgcgggc cggctgctgtggaagaacaactgggtgacgttcctggacgccatgctgcagacatccatc ctgggcctggcccagcgcggcctgcgtctgcccacccgcatcacctccgtccgcatcgac cccgccacccaccagcgcagggtgtactcgctgcagggcgaggcccaagcggtcaacgtg ctggtgaaccgttgtctgaacagcacggtggccggcggcgtcctcgtctcgggcctccac gcctcgatggccccacggcggcagcaggagcagtttgcacccatcctggagaagttctgc ttcacgccgcacacggaggaggggctcctggctggagacgcggccctgcaggaggggctg cagctgtgcagggggctggcacaggcgctgcagaccaaggtggcccagcaggggctgaag atggtggtgtctgggctggacggggcccaggccccccaggagcctccaaagcaaggcctg ccccggctgctggcggccgcctgccagctgcagctcaacgggggcctccagctggagctg ggccagctgctggcccaacagaggcccctgctgcaggacgaccccctgctcagcggcctc ctcgcttccccggcgctcaaggcctgcgtggacaccgccctggagaacatgcccagcctc aagatgaaggtcgtggaggtgctggctggcgatggccgcctgtattctcacatcccagcg ctgcttaacacccagcccatgctgcagctggagtacacggccactgaccgccaccctcag gccctggaggccgtgcaggccaagctgcagcagcacggcatagcccagggccagtgggac cctgcggaccacgcccctggcagcctgggctcggctgatctcctcctgtgtaactgtgcc gtggccagcctcagtgacccggccgtggccgttggcaacatgggggccgctctcaaggag ggcggcttcctgctgctgcacgctctgctcaaaggacacccccttggagagacggtcgcc ttcctcacctgccccgagccgcagcgaggccagcagagcctcctaagccaggaccagtgg gagagtctgtttgccggggcgtccctgcacctggtggccctgaagaagtccttctatggc tctgtgctcttcctgtgccgtcggccggtcctatgggacagccctgtcttcttgcctgta gaggaccccagtttccagtgggtgaactccctgaagaacattttggccgactcctcccag cagcccgtgtggctaacagccaccagctgccccgactcaggcatcgtgggcttggtgaac tgtctccgcagagagcctggcgggcaccggattcggtgcgtcctggtgtccaacctcagc agcacgtccagcacccccagtttggaccccggctcctcggagctgcagaaggtgctacgg ggggacctcgtgatgaatgtctaccgagacggcgcctggggggccttccgccatttcccc ctggagcgcggcctgccggaggagcagaccgagcacgccttcgtgaacgtcctcacgcgg ggcgacctctcctccatccgctgggtctgctcccctctgcgccacacccagctcaccggc cccggcacccatctctgtgccgtctactatgcctccctcaacttcagagacatcatgctg gccacgggcaagctgtcccctgacgccatcccagggaagtgggcccgccacgactgtttg ctgggcatggagttctctggccgagacgccagcggcaagcgtgtcatggggctggtgccc gccgaaggcctggctacctccgtcctgctctctcaggacttcctgtgggaggtgccctcc agctggaccctagaggaggcggcttcggtgcctgtggtctacaccaccgcctactactcg ctggtggtgcgggggcgtgtgcagcccggggagacggtgctcatccactcaggctcgggc ggcgtgggccaggccgccatcgccatcgccctcagcctgggctgccgcgtcttcactacc gtggggtcggccgagaagcgggcgtacctccaggccaggttcccccagctcgacgacacc agcttcgccaactcccgggacacgtcctttgaacagcatgtgctgcggcacacagcaggg aagggtgtggacctggtcctgaattctctggcggaagaaaagctacaggccagcgtgcgg tgcctggcccagcacggccggttcctggaaatcggcaaattcgacctttcgaacaaccac ctgctgggcatggccgtcttcctgaagaacgtgaccttccacggggttctgctggactcg ctcatggatgaaggtgggaacagctggcaggaggtggctgcgctgctgaaggcgggcatc cgggacggtgtggtgcagcccctcaagtgcaccgtgttccccaaggaccgggtggaggac gccttccgctacatggctcaagggaaacacatcggcaaagtggtcgtccaggtgcgcagg gaggagccggaggcggtgctgcgggagacgggtcccaccctgatggccgccgtgtccaag acctactgcccggcccacaagagctatgtcatcaccgggggcctgggcggcctcggcctg gagctggcccagtggcttgtgctgcgaggggcccggaaactcgtgctgacctctcgctct gggatccgcacaggctaccaggccaagcaggtccgtgagtggaggcgccagggcatacag gtcctggtgtccaccagcaatgccagctcgctggatggggcccagagcctcatcgatgag gccacgcagctggggcccgtgggaggcgtctttaacctggccgtggtcctgagagacgcc atgctggagaaccaaacccctgagctctttgaggacgtcgtcaggcccaagtacagcggc accgtgaacctggacagggtgacccgagctgcgtgccccgagctggactactttgtggcc ttctcctccgtgagctgcgggcgcggcaacgccggccagaccaactacggcttcgccaac tccaccatggagcgcgtgtgtgagaagcgccagcacgacggcctcccgggcctcgccatt cagtggggcgccgtcggtgacgtgggcatcgtcctggagtccatgggctccaacgatgtg gtcatcggcgggacgctgccgcagcggattgcctcctgcttggaggtgctggacgtcttc ctgaaccagccccaccccgtcctgagcagctttgtgctggccgagaagaaggccaccgcc cacaatgacagcagtagccggcaggacccgatggaggccgtggcccacatcctgggcatt cgagacttggccaccgtcaacctggacagctcgctggcagacctgggcctggactcgctc atgggcgtggaggtgcgccagatgttggagcgcgagcacgacctggtgatgtccatgcgg gacatccggcagctcacgctccggaagttgcaggagctttcctcgaaggctggcacagct aatgagctggcagcccccacacccaaggaggacacccctgccggccagcaggcccagctg aacctcagcaccctgctggtgaaccccgagggcccgaccctgacacggctcaactcggtg cagagctcggagcgccccttgttcctggtgcaccccatcgagggctccatcactgtgttc cgcagcctggcgtccaagctcagcatccccacctacggcctacagtgcactcgagccgcg cccctggacagcatccagagtctggccgcctactacatcgagtgcatcaggcaggtgcag ccggaggggccctaccgcatcgccggctattcctacggggcctgcgtggccttcgagatg tgctcgcagctgcaggccgcgcagcagggccccacccccgcgcacaacagcctcttcttg ttcgacggttcgcacacctatgtgctggcctacacacagagctaccgcgcgaagctgacc cctggctgtgaggccgaggccgaggccgaggccatgtgcttcttcgtgcagcagttcact gacatggaacacaacagggtcctggaggcactgctgcccctcaagggcctggaggagcgc gtggcggccaccgtggacctgatcacgcgcagccacgcgggcctggacccccgcgagctg agcttcgcggcacgctccttctaccacaagctgcgcgcggccgagcagtacatcccccgg gacacctaccacggcaacgtgacgctgctgcgcaccaagacgggcagcgtgtacggcgag ggcctgggcgccgactacaacctgtcccaggtgtgcgacggcaaggtgtccgtgcacgtg atcgagggggaccaccgcacgctgctggagggcagcggcctggagactatcctcagcatc atccacagctccctggccgagccgcgcgtcagcgtccgggagggctaa

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