Felis catus (domestic cat): 101081937
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Entry
101081937 CDS
T02385
Symbol
BRCA1
Name
(RefSeq) breast cancer type 1 susceptibility protein isoform X1
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca01524
Platinum drug resistance
fca03440
Homologous recombination
fca03460
Fanconi anemia pathway
fca04120
Ubiquitin mediated proteolysis
fca04151
PI3K-Akt signaling pathway
fca05206
MicroRNAs in cancer
fca05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
101081937 (BRCA1)
09124 Replication and repair
03440 Homologous recombination
101081937 (BRCA1)
03460 Fanconi anemia pathway
101081937 (BRCA1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
101081937 (BRCA1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
101081937 (BRCA1)
09162 Cancer: specific types
05224 Breast cancer
101081937 (BRCA1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
101081937 (BRCA1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
fca01009
]
101081937 (BRCA1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
fca04121
]
101081937 (BRCA1)
03036 Chromosome and associated proteins [BR:
fca03036
]
101081937 (BRCA1)
03400 DNA repair and recombination proteins [BR:
fca03400
]
101081937 (BRCA1)
Enzymes [BR:
fca01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
101081937 (BRCA1)
Protein phosphatases and associated proteins [BR:
fca01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
101081937 (BRCA1)
Ubiquitin system [BR:
fca04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
101081937 (BRCA1)
Multi subunit type E3
BRCC complex
101081937 (BRCA1)
Chromosome and associated proteins [BR:
fca03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
101081937 (BRCA1)
DNA repair and recombination proteins [BR:
fca03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
101081937 (BRCA1)
BRCA1-A complex
101081937 (BRCA1)
BRCA1-B complex
101081937 (BRCA1)
BRCA1-C complex
101081937 (BRCA1)
BRCA complex
101081937 (BRCA1)
FA (Fanconi anemia) pathway
Downstream FA components
101081937 (BRCA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BRCT_assoc
BRCT
zf-C3HC4
zf-C3HC4_2
zf-RING_UBOX
zf-C3HC4_4
zf-C3HC4_3
zf-RING_2
zf-RING_5
RING_XB3-XBAT31
BRCT_2
zf-Nse
zf-RING_6
zf-ANAPC11
zf-RING_10
zf-rbx1
Prok-RING_4
Motif
Other DBs
NCBI-GeneID:
101081937
NCBI-ProteinID:
XP_019673492
LinkDB
All DBs
Position
E1:complement(41522244..41581030)
Genome browser
AA seq
1873 aa
AA seq
DB search
MDLSADRVEEVQSVLNAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQRKGPSQ
CPLCKNDITKRSLQESTRFSQLVEELLNIIHAFELDTGLQFANSYNFSKKENNSPEHLKE
EVSIIQSMGYRNRAKRLRQSEPENPNLQETSLSVQLSNFGIVRSLRTKQQIQPQNKSVYI
ELGSDSSEDTVNKASYFSAEDDELLGITPQGARAEASLNPAKKASCEFSEDITNIEHRQP
SNKDLTATEKHATEKHPEKYQGISVSNLHVEPCATNTRASSLQHENSSLLLTKGRMNVEK
AEFCNESKQPGVARSQQSRWAESKETCNDRQTPSTEKKVVLNADPLCRRKLSKQKSPCSD
SPRDSQDVPWITLNSSIQKVNEWFSRSDEMLTSDDSHDEGSESNPGVAGAEVPNVVDGYS
GSSEKIDLMASDPHDALICESERVHTKPVESNIEDKIFGKTYRRKASLPNLSHTSEDLII
GACAIEPQITQAYPLTNKTKRKRRSTAGLHPEDFIKKVDLAIVQKTPEKLIEGTDRIGQN
GHVMNRTNNGPENGTKGDYVQKEKNAKPTESLEKESAFRTKAEPISSNISNMESELNSHS
SRAPKENRLRRKSSTRHMRALELVVNRNPSPPDHTELQIDSCSSSEEMVKRKSSEQMLVR
HSKTLQLVENKEPAPGAKKRNKPSKQINKRLASNTFPELNLTNIPGVFTNCSSSNTLQEF
VNPGIQREELEESRGTIHVSDRTRDPKALVSSGGRSLQTERSVESTSISLVPDADYGTQD
SISLLEADTLGKAKTAPNQRVSLCAAIENPKEAIRGCSKDTRNGTESFTDPLRREDNHTQ
ETSIEMEENELDTQCLYNTFKVSKRQSFALFSNPGNPEKECATAWARSTSLRKQSPKVAL
EYEQKEENQGKKQSEIKHVQAVRATAGFSAVSQKVEKPGDYAKCSIKGVPGLCQSSQFRG
NETELFIANNHDISKNPYHIPPLSPIRSSVNAVCKKNLSEEKFEQRSMSPERAVGNESVI
QSTVNTISQNNIRENTFKEVSSSSVNEVGSSANEVGSSINEVGSSGENIQTELGRNRGPK
LSAMLRLGLMQPEVYEQSLPISNCKCPEMKRQGENEGVVQSVNADFSPCLISDNVEQPME
SSRASQVCSETPNDLLNGDEIKGKISFAESAKERSAVFGKSVQKGEFRRSPSPLDHTHLA
QGHQTETRKLESSEENVSSEEEELPCFQHLLFGKVTSIPSQSTSHNAIATEGLSKKTEAN
LESLKDSLHDCSNQVTSAKESQEHHLSEEARCSGSLFSSQCSASEDSAVNTNTQDPFLMF
DPPSKQVRHQSENVDVLSDEELVSYDDEREPGLEEDNHEEEQSVDSNLGEAASGYENETS
LSEDCSGVSSQSDILTTQQRDTMQDNLIKLQQEMAELEAVLEQHESQPSNSSPALIRDSY
APEDLFNPEQNTSEKAVLTSEKSSDCLISQNPESLSADKFQVSLDSSTSKTKEPGMRRSS
PSQSRLLDTRQCVRSHSSSLQSTNCLSQKELIKAVDGEELQLTKSEPRDFMEQSYLPRQD
LEGTPYFESGISLFSDDPESDFSVDRAPEPVHVSSMPASTSALKLPQFQVEESAKSTAAV
HITNTAGYNKREDIEGKERPEMMSSTKRVNKRISMVASGLTPKELVLVQKFARRHQITLT
NVISEETTHVIMKTDAEFVCERTLKYFLGIAGGRWVVSYFWVTQSIKERKMLDEHDFEVR
GDVVNGRNHQGPKRARESRDRKIFGGLEICCYGPFTNMPTDQLEWMVRLCGASVVKRPSL
FTLSKATHPVVVVQPDAWTEDSGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQ
IPRATADLSQPCV
NT seq
5622 nt
NT seq
+upstream
nt +downstream
nt
atggatttatctgcagatcgtgttgaagaagtacaaagtgtccttaatgctatgcagaaa
atcttagagtgtccaatctgtctggagttgatcaaagagcctgtttccacaaagtgtgat
cacatattttgcaaattttgtatgctgaaacttctcaaccagaggaaagggccttcacag
tgtcctttgtgtaagaatgatataaccaaaagaagcctacaggaaagtacaagatttagt
caacttgttgaagagctgttgaacatcattcatgcttttgagcttgacacaggattgcag
tttgcaaacagctataacttttcaaaaaaggaaaataactctcctgagcatctgaaggag
gaggtttctattatccaaagtatgggctatcgaaaccgtgctaaaagacttcgacagagt
gaacctgaaaaccctaacttgcaggaaaccagtcttagtgtccaactctctaactttgga
attgtgagatctctgaggacaaagcagcagatacaaccacagaataagtctgtctacatt
gaattgggatctgattcttctgaagatacagtgaataaggcaagttatttcagtgcggaa
gatgacgaattgttaggaatcacccctcaaggagccagagctgaagccagtttgaatcct
gcaaaaaaggcctcttgtgaattttctgaggacataacaaatattgaacatcgtcaaccc
agtaataaagatttgaccgccactgagaagcatgcaactgaaaagcatccagaaaagtat
cagggtatttctgtttcaaacttgcatgtggagccatgtgccacaaatactcgtgccagc
tcattacagcatgagaacagcagtttattactcactaaaggcagaatgaatgtagaaaag
gctgaattctgtaatgaaagcaaacagcctggcgtagcaaggagccaacagagcagatgg
gctgaaagtaaggaaacatgtaatgataggcagactcccagcacagagaaaaaggtagtt
ctgaatgctgatcccctgtgtaggagaaaactgagtaagcagaaatctccatgctctgac
agtcctagagattcccaagatgtaccttggataacactgaatagtagcatacagaaagtt
aatgagtggttttccagaagtgatgaaatgttaacttctgatgactcacatgatgaggga
tctgaatcgaatcctggagtagctggtgcagaagttccaaatgtagtggatggatattct
ggttcttctgagaaaatagacttaatggccagtgatcctcatgatgctttgatatgtgaa
agtgaaagagttcacaccaaaccagtagagagtaatattgaagataaaatatttgggaaa
acctatcggaggaaggcaagccttcctaacttgagccacacaagtgaagatctcattata
ggagcatgtgctatagaacctcagataacgcaagcctatcccctcacaaataaaacaaag
cgtaaaaggagatctaccgcaggccttcatcctgaggattttatcaagaaagtagatttg
gccattgttcaaaagactcctgaaaagctaattgagggaaccgatcgaatagggcaaaat
ggccatgtgatgaatagaacaaataatggtcctgagaatgggacaaaaggtgattatgtt
cagaaagagaaaaatgctaagccaacagaatcattggaaaaagaatctgcttttagaacc
aaagctgaaccaataagcagcaatataagtaatatggaatcagaattaaatagccacagt
tcaagggcacctaaggagaacaggctgaggaggaagtcctctaccaggcacatgcgtgcg
ctggaattagtagtcaatagaaatccaagcccacctgatcataccgaactacagattgat
agttgttctagcagtgaagagatggtgaaaagaaaaagttcggaacaaatgctagtcaga
cacagcaaaacacttcaactcgtggaaaataaagaacctgcacctggagccaagaagcgt
aacaagccaagtaaacaaataaataaaagacttgccagtaacacttttccagagctaaat
ttaacaaacatacctggggtttttactaactgttcaagttctaatacacttcaagagttt
gtcaaccctggcattcaaagagaagaactagaagagagccgaggaacgattcacgtgtct
gataggaccagagatcccaaagcgctggtatcgagtggaggaagaagtttgcaaactgaa
agatctgtagagagtaccagtatttcattggtacctgatgccgattatggcactcaggat
agtatctcattactggaagctgacaccctagggaaggcaaaaacagcaccaaatcaacgt
gtgagtctgtgtgcagcaattgaaaaccccaaggaagctatccgtggttgttccaaagat
actagaaatggcacagagagttttacagatcctctgagacgtgaagataaccatactcag
gagacaagtatagaaatggaagagaatgaacttgatacgcagtgtttatacaatacgttc
aaggtttcaaaacgtcagtcatttgctctgttttcaaatccaggaaacccagaaaaggaa
tgtgctacagcctgggcccgttccacgtccttaaggaaacaaagtccaaaagtcgctctt
gaatatgaacaaaaagaagaaaatcagggaaagaaacagtctgaaatcaagcatgtgcag
gcagtccgtgcaactgcaggcttttctgcagtcagtcagaaagtggagaagccaggtgat
tatgccaaatgtagcataaaaggagtccctgggctctgtcagtcatctcagttcagaggc
aatgaaactgaactctttattgcaaataaccatgacatttcaaaaaacccttatcatata
ccaccactttctcccatcagatcatctgttaatgctgtatgtaagaaaaacctgtcagag
gaaaagtttgagcagcgttcaatgtcacctgaaagagcagtgggaaatgagagcgtcatt
caaagtacagtgaacacaattagccaaaataacattagagaaaacacttttaaagaagtt
agctcaagcagtgttaatgaagtaggttccagtgctaatgaagtaggctctagcattaat
gaagtaggttccagtggtgaaaacattcaaacagaactgggtagaaaccgaggacctaag
ttaagtgctatgctcaggttaggtcttatgcaacctgaagtctatgagcaaagtcttcct
ataagtaattgtaaatgtccagaaatgaaaaggcaaggagaaaatgaaggagtagttcag
tctgttaatgcagatttttctccatgtctaatttccgataatgtagaacaacctatggaa
agtagccgtgcttctcaggtttgttctgagacacccaatgacctattaaatggtgatgaa
ataaagggaaaaatcagctttgctgaaagtgctaaggaaagatctgctgtttttggcaag
agtgtccagaaaggagaattcagaaggagccctagccctttagaccatacacatctggct
cagggtcaccaaacagagaccaggaagttagagtcctcagaagagaacgtgtctagtgag
gaggaagagcttccctgcttccaacacttactatttggtaaagtaaccagtataccttct
cagtctaccagccataatgccattgccacggagggtctgtctaagaaaacagaggcgaac
ctagaatcattgaaggatagcttacatgactgcagtaaccaggtaacatcagcaaaggag
tcccaggaacatcaccttagtgaggaagcgaggtgttccggtagcttattttcttcacag
tgcagtgcatcggaagactcggctgttaatacaaatacccaggatcctttcttgatgttt
gatcctccttccaaacaagtgaggcatcagtccgaaaatgtggacgttctgagtgatgag
gaattggtttcatatgatgatgaaagggaacctggcctggaagaggataatcacgaagaa
gagcagagtgtggattcaaacttaggtgaagcagcatctgggtacgagaatgaaacaagc
ctctctgaagactgttcaggggtgtcctctcagagtgatattttaaccactcagcagagg
gataccatgcaagacaacctgatcaagctccagcaggaaatggccgaactggaagccgtg
ttagagcagcacgagagccagccttctaacagctcccctgccctcataagagattcttat
gcccctgaggacctgttcaatccggaacaaaacacatcagagaaagcagtattaacttca
gagaaaagtagtgactgccttataagccagaatcccgaaagcctctctgctgacaaattt
caagtatctctggatagttccaccagtaaaactaaagaaccgggaatgagaaggtcttct
ccttctcaatcccggctgttagatactaggcagtgtgtgcgcagccactcaagcagtctt
cagagcacaaactgcctgtctcagaaggagctaattaaggctgtcgatggggaggagcta
caactgactaagtcagagccccgagatttcatggagcagtcttatttgccaagacaagat
ctggagggaaccccttacttcgaatctggaatcagcctcttctctgatgaccctgagtct
gatttctctgtggacagagccccagaaccggttcatgttagcagcatgccagcttcaacc
tctgccttgaaattaccccaatttcaagttgaagaatcagccaagagtacagctgctgtt
catattactaatactgctgggtataataagagggaagacattgagggcaaggagaggcca
gaaatgatgtcttcaacaaaaagagtcaacaaaagaatatctatggtggcatcaggcttg
actccaaaagaattggtgcttgtgcagaagtttgccagaagacaccaaatcaccttaact
aatgtaatttctgaagagactactcatgtcattatgaaaacagatgctgagtttgtgtgt
gaacggacactgaaatattttctgggtattgcaggaggacgatgggtagttagctatttc
tgggtgacccagtccattaaagaaagaaagatgctagatgagcatgattttgaagtcaga
ggagatgttgtcaatggaagaaaccaccagggtccgaagcgagcaagagaatcccgggac
agaaagatcttcgggggcctagaaatctgttgctatgggccctttaccaacatgcccaca
gatcaactagagtggatggtgcgcctctgtggggcttctgtggtgaagaggccttcgtta
ttcactctcagcaaggctactcacccagttgtggtcgtgcaaccggatgcctggacagag
gacagtggcttccatgcgattgggcagatgtgtgaggcacctgtggtgacccgagagtgg
gtattggacagtgtagccctctaccagtgccaggagctggacacctacctgatcccccag
attcccagagctactgctgacctcagccagccatgtgtgtag
DBGET
integrated database retrieval system
