Felis catus (domestic cat): 101082923
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Entry
101082923 CDS
T02385
Symbol
CACNA1C
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1C isoform X1
KO
K04850
voltage-dependent calcium channel L type alpha-1C
Organism
fca
Felis catus (domestic cat)
Pathway
fca04010
MAPK signaling pathway
fca04020
Calcium signaling pathway
fca04022
cGMP-PKG signaling pathway
fca04024
cAMP signaling pathway
fca04260
Cardiac muscle contraction
fca04261
Adrenergic signaling in cardiomyocytes
fca04270
Vascular smooth muscle contraction
fca04713
Circadian entrainment
fca04720
Long-term potentiation
fca04723
Retrograde endocannabinoid signaling
fca04724
Glutamatergic synapse
fca04725
Cholinergic synapse
fca04726
Serotonergic synapse
fca04727
GABAergic synapse
fca04728
Dopaminergic synapse
fca04742
Taste transduction
fca04911
Insulin secretion
fca04912
GnRH signaling pathway
fca04921
Oxytocin signaling pathway
fca04924
Renin secretion
fca04925
Aldosterone synthesis and secretion
fca04927
Cortisol synthesis and secretion
fca04929
GnRH secretion
fca04930
Type II diabetes mellitus
fca04934
Cushing syndrome
fca04935
Growth hormone synthesis, secretion and action
fca05010
Alzheimer disease
fca05020
Prion disease
fca05022
Pathways of neurodegeneration - multiple diseases
fca05031
Amphetamine addiction
fca05207
Chemical carcinogenesis - receptor activation
fca05410
Hypertrophic cardiomyopathy
fca05412
Arrhythmogenic right ventricular cardiomyopathy
fca05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101082923 (CACNA1C)
04020 Calcium signaling pathway
101082923 (CACNA1C)
04024 cAMP signaling pathway
101082923 (CACNA1C)
04022 cGMP-PKG signaling pathway
101082923 (CACNA1C)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
101082923 (CACNA1C)
04929 GnRH secretion
101082923 (CACNA1C)
04912 GnRH signaling pathway
101082923 (CACNA1C)
04921 Oxytocin signaling pathway
101082923 (CACNA1C)
04935 Growth hormone synthesis, secretion and action
101082923 (CACNA1C)
04924 Renin secretion
101082923 (CACNA1C)
04925 Aldosterone synthesis and secretion
101082923 (CACNA1C)
04927 Cortisol synthesis and secretion
101082923 (CACNA1C)
09153 Circulatory system
04260 Cardiac muscle contraction
101082923 (CACNA1C)
04261 Adrenergic signaling in cardiomyocytes
101082923 (CACNA1C)
04270 Vascular smooth muscle contraction
101082923 (CACNA1C)
09156 Nervous system
04724 Glutamatergic synapse
101082923 (CACNA1C)
04727 GABAergic synapse
101082923 (CACNA1C)
04725 Cholinergic synapse
101082923 (CACNA1C)
04728 Dopaminergic synapse
101082923 (CACNA1C)
04726 Serotonergic synapse
101082923 (CACNA1C)
04720 Long-term potentiation
101082923 (CACNA1C)
04723 Retrograde endocannabinoid signaling
101082923 (CACNA1C)
09157 Sensory system
04742 Taste transduction
101082923 (CACNA1C)
09159 Environmental adaptation
04713 Circadian entrainment
101082923 (CACNA1C)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
101082923 (CACNA1C)
09164 Neurodegenerative disease
05010 Alzheimer disease
101082923 (CACNA1C)
05020 Prion disease
101082923 (CACNA1C)
05022 Pathways of neurodegeneration - multiple diseases
101082923 (CACNA1C)
09165 Substance dependence
05031 Amphetamine addiction
101082923 (CACNA1C)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
101082923 (CACNA1C)
05412 Arrhythmogenic right ventricular cardiomyopathy
101082923 (CACNA1C)
05414 Dilated cardiomyopathy
101082923 (CACNA1C)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
101082923 (CACNA1C)
04934 Cushing syndrome
101082923 (CACNA1C)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
fca04040
]
101082923 (CACNA1C)
Ion channels [BR:
fca04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
101082923 (CACNA1C)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
GPHH
CAC1F_C
PKD_channel
Motif
Other DBs
NCBI-GeneID:
101082923
NCBI-ProteinID:
XP_044917095
LinkDB
All DBs
Position
B4:complement(35428109..36181496)
Genome browser
AA seq
2252 aa
AA seq
DB search
MLRAFVQPAAPAYQPLPRHPSAESEAKFKGTLVHEAQLNCFYIPPGGSNYGSPRAAHANM
NANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTISSTQRKRQQYGKPK
KQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPED
DSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSA
ILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLH
IALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQNGT
VCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVI
FGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPE
NEDEGMDEEKPRNRSTPAGLLDQKKGKFAWFSHSTETHVSMPTSETESVNTENVAGGDIE
GENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEH
YNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETIL
VETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIF
SLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFP
GMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPE
KKQEIMEKPAVEETKEEKIELKSITADGESPPTTKINMDDLQPNENEDKSPYPNPENTGE
DDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNL
ILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVFTSIFT
LEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRP
LRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQT
EAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSI
DSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKN
QRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSC
LFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNH
YFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPFMNAEENSRISITFFRLFRVMRLV
KLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNN
NFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFI
SFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDV
VTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGN
LEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQ
GLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFR
RAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGNSQGDTESPSHEKLVDSTFTPSS
YSSTGSNANINNANNTALGRFPRPAGYPSAVSTVEGHGPPLSPAVRVQEAAWKLSSKRTH
CYDVLGRCHSRESQIAMVCQEEVSQDETYDVKISEDTEYCSEPSLISTEMLSYQDDENRQ
LTPPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKNQGGDISQKTVLPLHLVHHQ
ALAVAGLSPLLQRSHSPSTSPRPCATPPATPGSRGWPPQPIPTLRLEGAESNEKLNSSFP
SIHCSSWSGEPTPCGGGGSTIRRARPVSLTVPGQAGAQGRQFHGSASSLVEAVLISEGLG
QFAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQDR
AEGQEGETCAPTLACRKSEEELQDSRAHVGSL
NT seq
6759 nt
NT seq
+upstream
nt +downstream
nt
atgcttcgagcctttgttcagcctgctgcgcctgcataccagccgcttcccaggcaccct
tctgccgagtcagaggcgaagtttaagggcactttggtgcatgaagctcaactcaactgt
ttctacatccctcctggaggttccaactatgggagcccgcgtgcagctcacgccaacatg
aatgccaatgcggctgcggggctcgcccccgagcacatcccaacgcctggggcagccttg
tcctggcaggcagccatcgacgcggcccggcaggctaagctgatgggcagcgctggcaat
gcaaccatctccaccatcagctccacacagcggaagcggcagcaatatgggaaacccaag
aagcagggcagcacgactgccacacgcccgccccgtgccctgctctgcctgactctgaag
aaccccatcaggagggcgtgcatcagcatcgtcgaatggaaaccatttgaaataattatt
ttactgactatttttgccaattgtgtggccttagcgatctatattccctttccagaagat
gactccaatgccaccaattccaacctggaacgagtggaatatctctttctcataattttt
actgtggaagcatttttaaaagtaatagcctatggacttctctttcaccccaacgcttac
ctccgcaatggctggaatttactagattttataattgtggttgtagggctttttagtgca
attttagaacaagccaccaaagctgatggggcaaatgctctaggaggtaaaggagctgga
tttgatgtgaaggcactgagggcattccgcgtgctgcgccccttgcggctggtgtctgga
gtcccaagtctccaagtcgttctgaattccattatcaaggccatggtccccctgctgcat
attgccctgttagtgctatttgtcatcatcatctacgctatcattggcctggagctcttc
atgggaaagatgcataagacctgctacaaccaggagggcatagcagatgttccagcagaa
gatgatccttccccttgtgctctggagactggccatgggcggcagtgccagaatggcact
gtgtgcaagcctggctgggacgggcccaagcacggcatcaccaactttgacaattttgcc
ttcgccatgttgacagtgttccagtgcatcaccatggagggctggacagatgtgctatac
tggatgcaggacgctatgggctatgagttaccctgggtgtattttgtcagtctggtcatc
tttggatcctttttcgttctaaatctggttctcggtgtgttgagcggagagttttccaaa
gagagagagaaggccaaggctcggggagacttccagaagctgcgagagaagcagcagctg
gaagaggacctgaagggctacctggactggatcacccaggcagaggacatcgaccctgag
aacgaggacgaaggcatggatgaggagaagccccgaaacagaagcactccagcgggcttg
cttgatcagaagaaagggaagtttgcttggtttagtcactccacagaaacccatgtgagc
atgcccacaagtgagaccgagtctgtcaacaccgaaaacgtggctggaggtgacatcgag
ggagagaactgcggggccaggctggcccatcggatttccaaatcaaagttcagccgctac
tggcgtcggtggaatcggttctgcagaagaaagtgtcgtgctgcagtcaagtctaatgtc
ttctactggcttgtgatcttcctggtgttcctcaacacactcaccattgcctcagaacat
tacaaccagccccactggctcacggaggtccaagacacggccaacaaggcactactggcc
cttttcactgcggagatgctgctaaagatgtacagcctgggcctgcaggcctactttgtg
tccctcttcaaccgctttgactgcttcatcgtgtgtgggggcattctggagaccatcctg
gtggagaccaagatcatgtctcccttgggcatctctgtgctgagatgtgtccggctactg
cggatatttaaaatcacaaggtactggaactccttaagcaacctggtggcatccttgctg
aattctgtgcgctccattgcctccctgctgctactcctcttcctcttcatcatcatcttc
tccctcctggggatgcagctctttggaggaaagttcaactttgatgagatgcagactcgg
aggagcacatttgataactttcctcagtccctcctcaccgtgtttcagatcctgaccggg
gaggactggaattcggtgatgtatgatgggatcatggcttatggcggcccctcttttcca
gggatgttagtctgtatttacttcatcatcctcttcatctgtggaaactatatcctactg
aatgtgttcttggccattgctgtggacaacctggctgatgctgagagcctcacatctgcc
caaaaggaggaggaagaagagaaggagagaaagaagctggccaggactgccagcccagag
aagaagcaagagataatggaaaagccagctgtggaggaaaccaaggaggagaaaattgag
ctgaaatccattacagctgatggagagtccccacccaccaccaagatcaacatggatgac
ctccagcccaatgaaaatgaagataagagtccctaccccaacccagaaaatacaggagaa
gacgatgaagaggagcctgagatgcctgtgggcccccgcccacgaccactctctgagctg
caccttaaggaaaaggcagtgcccatgccagaagccagtgcatttttcatcttcagcccc
aacaacagatttcgcctccagtgccaccgcattgtcaatgacacgatcttcaccaacctg
atcctcttcttcattctgctcagcagcatttccctggcagctgaggaccctgtccagcac
acctccttcaggaaccatattctgttttattttgacattgttttcactaccattttcacc
attgaaattgctctgaagatcctaggcaatgcagactatgtcttcactagtatctttaca
ttagaaattatccttaagatgactgcttatggggctttcttacacaagggctctttctgc
cggaactacttcaacatcttggacctgctggtggtcagcgtgtccctcatttcctttggc
atccagtccagtgcaattaatgtggtgaagatcttgcgagttctgcgagtcctcaggccc
ctgagggccatcaacagggccaaggggctaaagcacgtggtccagtgcgtgtttgtcgcc
atccggaccatagggaatatcgtgattgtcaccacgctgctccagttcatgttcgcctgc
atcggggtccagcttttcaagggaaagctctacacctgttcagatagttccaagcagacc
gaggcggaatgcaagggtaactacatcacatacaaggatggggaagttgaccaccccatc
atccagcctcgcagctgggaaaacagcaagtttgactttgacaatgttctggcagccatg
atggccctctttaccgtctccacctttgaggggtggccagagctgctgtaccgctccatc
gactcccacacagaagacaagggccccatctacaactaccgtgtggagatctccatcttt
ttcatcatctacatcatcatcattgccttcttcatgatgaacatcttcgtgggttttgtc
atcgtcaccttccaggagcagggggagcaggaatacaagaactgtgaactggacaagaac
cagcgacagtgtgtggaatatgccctcaaggcccggcccctgcggaggtacatccccaaa
aaccagcaccagtacaaagtgtggtacgtggtcaactccacctactttgaatacctgatg
ttcgtcctcatcctgctcaacaccatctgcttggcaatgcagcactatggccagagctgc
ctattcaaaatcgccatgaacatcctcaacatgctcttcactggcctcttcactgtggag
atgattctgaagctcattgccttcaaacccaagggttactttagtgatccctggaatgtt
tttgacttcctcatcgtaattggcagcataattgacgtcattctcagtgaaactaatcac
tatttctgtgatgcatggaatacatttgacgccttgattgttgtgggtagcattgttgat
atagcaatcaccgaggtaaacccagctgaacatacccaatgctctccctttatgaacgca
gaggagaactcccgcatctccatcaccttcttccgcctcttccgggtcatgcgactggtc
aagctgctaagccgtggggagggcatccggaccctgctgtggaccttcatcaagtccttc
caggctttgccctatgtggcccttctgatagtgatgctgttcttcatctacgcagtgatc
gggatgcaggtgtttgggaaaattgccctgaatgacaccacagagatcaaccggaacaac
aactttcagaccttcccccaagctgtgctccttctcttcaggtgtgccacaggggaggca
tggcaagacatcatgctggcctgcatgccagggaagaagtgtgcccccgagtcagagccc
agcaacagcacggaaggggaaacgccctgtggcagcagttttgccgtcttctacttcatc
agcttctacatgctctgtgccttcctgatcatcaacctctttgtagctgtcatcatggac
aactttgactacctgacaagagactggtcaatccttggtccccatcatctggatgaattt
aaaagaatctgggcagagtatgatcctgaagctaagggtcgtatcaaacacctagatgtg
gtgaccctgctccggcggattcagcccccactgggttttgggaagctgtgccctcaccgc
gtggcttgcaaacgcctggtctccatgaacatgcctctgaacagtgatgggactgtcatg
ttcaatgccaccctgtttgccctagtccggacagccctgcggatcaaaacagaagggaac
ctagaacaagccaatgaggagctgcgggccataatcaagaagatctggaagcgtaccagc
atgaagctgctagaccaagtggtgccccctgcaggtgatgatgaggtcaccgttggcaag
ttttatgctactttcctgatccaagagtacttccggaaattcaagaagcgcaaagagcag
ggccttgtgggcaagccttcccaaaggaatgccctgtccttgcaggctggcttgcgcacg
ctgcatgacattgggcctgagatccgacgggccatctctggagatctgacagctgaggag
gagctggacaaggccatgaaggaggctgtgtctgctgcctccgaagatgacatcttcagg
agggccggtggcctgttcggcaaccacgtcagctactaccaaagcgacggccggagcgcc
ttcccccagaccttcaccacccagcgcccactgcacatcaacaaggcgggtaacagccaa
ggcgacaccgagtcgccatcccacgagaaactggtggactccaccttcacccccagcagc
tactcgtccactggctccaacgccaacatcaacaatgccaacaacactgccctgggccgc
ttcccccgtcccgctggctaccccagcgcagtcagcaccgtggagggccatgggcccccc
ttgtctcctgctgtccgggtacaggaggcagcatggaagctcagctccaagaggacacat
tgctatgatgtgctgggacggtgccactcccgggagagccagatagccatggtgtgtcag
gaggaggtctctcaggacgagacctatgacgtgaagataagtgaagacactgagtactgc
agcgagcccagcctgatctccacagagatgctctcctatcaggatgatgaaaatcggcaa
ttaacaccaccggaggaggacaagagagatatccggcaatctccaaagaggggcttcctc
cgctctgcctcactaggtcgaagggcctccttccacctggaatgtctgaagcgacagaag
aatcaagggggagacatctctcagaagacagtcctgcccttgcatctggttcatcatcag
gcattggcggtggcaggcctgagccccctcctccagagaagccattcccccagcacatcc
cccaggccctgtgccaccccaccagccactccaggcagccgaggctggcccccacagcct
atccccaccctgcggctggagggtgccgaatccaacgagaaactcaacagcagcttcccg
tccatccactgcagctcctggtctggggagcccacaccctgtggtggaggtggcagcacc
atccggagagcccggccagtgtccctcactgtgcccggccaggctggggcccagggcagg
cagttccacggcagtgccagcagcctggtagaagcggtcttgatttcagaaggactgggg
cagtttgctcaagatcccaagtttattgaggtcacaacccaggagctggctgacgcctgt
gacatgaccatagaggagatggagaacgccgcagacaacatcctcagtgggggcgcccag
cagagccccaatggcaccctactacctttcgttaactgcagggacccagggcaggacaga
gcagagggccaagagggcgagacctgcgcgcccaccctggcgtgtcggaagagcgaggag
gagctccaggacagcagagcccacgtcggcagcctgtag
DBGET
integrated database retrieval system
