Felis catus (domestic cat): 101086133
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Entry
101086133 CDS
T02385
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca04120
Ubiquitin mediated proteolysis
fca04144
Endocytosis
fca04330
Notch signaling pathway
fca04668
TNF signaling pathway
fca04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
101086133 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
101086133 (ITCH)
04668 TNF signaling pathway
101086133 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
101086133 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
101086133 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
fca04131
]
101086133 (ITCH)
04121 Ubiquitin system [BR:
fca04121
]
101086133 (ITCH)
Enzymes [BR:
fca01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
101086133 (ITCH)
Membrane trafficking [BR:
fca04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
101086133 (ITCH)
Ubiquitin system [BR:
fca04121
]
Ubiquitin ligases (E3)
HECT type E3
101086133 (ITCH)
BRITE hierarchy
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Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
101086133
NCBI-ProteinID:
XP_003983646
UniProt:
A0ABI7YUG4
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Position
A3:complement(24593185..24739144)
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AA seq
862 aa
AA seq
DB search
MSGSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIFETLKSNNMKLEEVVVTL
QLVGDKEPTETMGDLSVCLDGLQLEPEVVTNGETTCSESASQNDDGSRPKDEARTNPNGS
DEPEDSGAGENRKVNGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESD
GSSTGSLPPTNINSNTSEGATSGLIIPLTISGGSGPRPLNTVPQAPLPPGWEQRVDQHGR
VYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFTTSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNT
RITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFNPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
GRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGL
EMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctggcagtggatcgcagcttggttcaatgggtagcctgaccatgaaatcacagctt
cagatcactgtcatttcagcaaaacttaaagaaaataaaaagaattggtttggaccaagt
ccttatgtggaagtcacagttgatggacagtcaaagaagacagaaaaatgcaacaatacg
aacagtcccaaatggaagcaaccccttacagttattgtcacccctgtgagtaaattgcat
tttcgcgtgtggagtcatcagacactgaaatctgatgttttgttgggaactgctgcatta
gatatctttgaaaccttaaagtcaaacaacatgaaacttgaggaagtagttgtgacttta
cagcttgtaggtgacaaagagccaacagagacaatgggagacttgtcagtttgtcttgat
gggctgcagttagagcctgaagttgttaccaatggtgaaactacatgttcagaaagtgct
tcacagaatgatgatggctctagaccgaaggatgaagcaagaacaaatccaaatggatca
gatgaacctgaggattcaggggctggtgaaaataggaaggtcaatgggaataattctcca
tcactctcaaatggcggttttaaaccttctaggcctccaagaccttcacgaccacctcca
cctaccccacgtagaccagcatctgtcaatggttcaccatctgctacttctgaaagtgat
ggatccagtacaggctctctgccaccaacaaatataaattcaaatacatctgaaggagca
acatctggattaataattcctcttactatatctggaggctcaggccctaggccattaaat
actgtacctcaagctcccctaccacctggttgggagcagagagtggaccagcatgggcga
gtttactacgtagatcatattgaaaaaagaacaacgtgggatagaccagaacctctacct
cctggctgggaacggcgggttgacaacatgggacgtatttattatgttgaccatttcaca
agaacaacaacgtggcagaggccgacattggaatctgtccggaactatgaacagtggcaa
ctccaacgtagtcagcttcaaggagcaatgcagcaatttaaccagagattcatttatggg
aatcaggatttgtttactacatcgcaaaataaagaatttgatccccttggtcccctgcct
cctggatgggagaagagaacagacagcaatggtagagtatattttgtcaaccacaacact
cgtattacacaatgggaggaccccagaagtcaaggtcaattaaatgaaaagcccttacct
gaaggctgggaaatgagattcacagtagatggaattccatattttgtggaccacaataga
agaacaaccacctatattgatccccgcactggaaaatctgctctagacaatggaccacag
atagcctacgtacgggacttcaaggcaaaggttcagtatttccgcttctggtgtcagcaa
ctggcaatgccacagcacataaagattacagtgacaagaaaaacattgtttgaagattcc
tttcagcagataatgagcttcaatccccaagatctgcgaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagagagtggttctttcttttgtca
cacgaggtgttgaaccccatgtattgcctgtttgaatatgcaggaaaggataactactgc
ctgcagattaatcctgcttcttacatcaatccagatcacctgaaatattttcgttttatt
ggcaggtttattgccatggctttgttccatgggaaattcatagacacaggtttttctttg
ccattctataagcgtatattgaacaaaccagttggactcaaggatttagaatctattgat
ccagaattttacaattctctcatctgggttaaagaaaacaatattgaggaatgtggtttg
gaaatgtacttctctgtcgataaagaaattttaggtgaaatcaagagtcatgatttgaaa
cctaatggtggcaatattcttgtgacagaagaaaataaagaggaatatatcagaatggta
gctgaatggaggttgtctcgaggtgttgaagaacagacacaagctttctttgagggcttt
aatgaaattcttccccagcagtatttgcaatactttgatgcaaaggaattagaggtcctt
ttatgtggaatgcaagagattgatttgaatgactggcaaagacatgccatctaccgtcat
tacactaggacaagcaaacaaatcatgtggttttggcagtttgttaaagaaattgataat
gagaagagaatgagacttctgcagtttgttactggaacttgtcgattgccagttggagga
tttgctgacctcatggggagcaatggaccacagaaattctgcattgaaaaagttgggaaa
gaaaactggttacccagaagtcatacctgttttaaccgcctggacctgccaccctacaag
agctatgagcaactgaaggaaaagctgttatttgccattgaagaaacagaaggatttgga
caagagtaa
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