Felis catus (domestic cat): 101086680
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Entry
101086680 CDS
T02385
Symbol
ACACB
Name
(RefSeq) acetyl-CoA carboxylase 2 isoform X1
KO
K01946
acetyl-CoA carboxylase / biotin carboxylase 2 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca00061
Fatty acid biosynthesis
fca00620
Pyruvate metabolism
fca00640
Propanoate metabolism
fca01100
Metabolic pathways
fca04152
AMPK signaling pathway
fca04910
Insulin signaling pathway
fca04920
Adipocytokine signaling pathway
fca04922
Glucagon signaling pathway
fca04931
Insulin resistance
fca04936
Alcoholic liver disease
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
101086680 (ACACB)
00640 Propanoate metabolism
101086680 (ACACB)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
101086680 (ACACB)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
101086680 (ACACB)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
101086680 (ACACB)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
101086680 (ACACB)
04922 Glucagon signaling pathway
101086680 (ACACB)
04920 Adipocytokine signaling pathway
101086680 (ACACB)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
101086680 (ACACB)
04931 Insulin resistance
101086680 (ACACB)
Enzymes [BR:
fca01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
101086680 (ACACB)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
101086680 (ACACB)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
101086680 (ACACB)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
Motif
Other DBs
NCBI-GeneID:
101086680
NCBI-ProteinID:
XP_003994907
LinkDB
All DBs
Position
D3:18160911..18271136
Genome browser
AA seq
2456 aa
AA seq
DB search
MTLLLFLSCLIFSCLTFSWLKFWGGMTDSKQVTQSTPEGSCSPSQAPFPASDSSGEPPQK
NDNNGPLPETPKRAEPASHKGADDTDQQRTSGPPPRQNPPGDSLSPDDTSPAPQANATGT
AALKTPDTDGPSSPAKPQGPRARPLSKKDKKQEHIKRQLMTNFILGSFDDNSSDEDPGAG
LFRESPRKGSRASLGTLSLEAAHTAGEPENPVPTIRPSMSGLHLVKKGRELKKVDLHRDF
TVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPE
DLKANAEYIKMADQYVPVPGGPNNNNYANVELVVDIAKRIPVQAVWAGWGHASENPKLPE
LLCKHEIAFLGPPSEAMWALGDKIASTIVAQTLQVPTLPWSGSGLMIEWAEDNLQEGKRI
SVPEDIYNQGCVKDVDEGLEVAEKIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQVQS
EIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIATPA
VFEFMEQCAVRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPA
AQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDEGF
KPSSGTVQELNFRSNKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVALK
ELSIRGDFRTTVEYLINLLETERFQNNDIDTGWLDHLIAEKVQAEKPDIMLGVVCGALNV
ADVMFRTCMTDFLHSLERGQVLPAASLLNIVDVELIYDGVKYILKVARQSLTMFVLIMNG
CHIEIDAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRVTIGNKTCVFEKENDPTVLRSPSA
GKLIQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQESGRVKYIKRAGAVLEAGCVVAKLE
LDDPSKVRPAEPFTGELPSQQTLPIVGEKLHQVFHNVLENLTNVMNGYCLPEPIFSTKLK
EWVQKLMTTLRHPSLPLLELQEIMTSVSGRIPAPVEKSVRRVMAQYASNITSVLCQFPSQ
QIATILDCHAATLQRKADREVFFMNTQSIVQLVQRYRSGTRGYMKAVVLDLLRRYLRVEH
HFQQAHYDKCVINLREQLKPNMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSEEL
TSILNELTQLSKSEHCKVALRARQILIASHLPSYELRHNQVESIFLSAIDMYGHQFCPEN
LKKLILSETTIFDVLPTFFYHTNKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCVVE
FQFMLPSSHPNRMAVPISVTNPDLLRHSTELFMDSGFAPLCQRMGAMVAFRRFEDFTRNF
DEVISCFANVPREIPLFRKACTPLYSEEENKSLREEPIHILNVAIQYADHLEDEELVPIF
RTFVQSKKNILVEYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQLEL
SRMRSFDLTAVPCANHKMHLYLGAAKVKEGAEVTDHRFFIRAIIRHSDLITKEASFEYLQ
NEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPFKIEESVRSMVMRYGSRL
WKLRVLQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDPRSGNIMFHSFGN
KQGPQHGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALLKLWGSTDNYPKDI
LTYTELVLDPQSQLVEMNRLPGGNEVGMVAFKMRFKTREYPEGRDAIVISNDITFRIGSF
GLGEDLLYLRASEMARAEGIPKIYLAANSGACIGLAEEIKHMFQVAWVDPGDPYKGFKYL
YLTPQDYTRISSLNSVRCKHIEEEGESRYVITDIVGKDRGLGVENLKGSGMIAGESSLAY
EEIVTISMVTCRALGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQLGG
VQIMHHNGVSHVTVPDDFEGVYTILEWLSYMPKDNRSPVPITTPSDPIDREIEFFPSRAP
YDPRWLLAGRPHPTLKGSWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETR
TVEVVVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAISDFNREGLPLIVFANWRGFSG
GMKDMYDQVLKFGAYIVDSLRQYKQPVLIYIPPHGELRGGSWVVVDSSINPLYIETYADK
ESRASILEPEGTVEIKFRKKDLIKTMRRIDPVYKKLVEQLGVSELADKDRKDLEGQLKAR
EDLLLPIYHQVAVLFADLHDRAYGMLEKGVVSDIVEWKTSRAFLYWRLRRLLLEDQVKQE
ILQASSELSHVHIQSMLRRWFVETEGAVKAYLWDNNQMVVKWLEQHWQGGGGLRSTIREN
IKCLKRDSVLKAIRRLVQENPDVAVDCIVYLSQHISSAERAEVIHLLSTMDSPAST
NT seq
7371 nt
NT seq
+upstream
nt +downstream
nt
atgaccttgcttctttttctatcttgtttgattttctcctgcttgaccttctcctggtta
aaattctgggggggaatgacagactccaagcaagtcacccagagcacacccgaagggagc
tgtagcccaagccaagcgccttttccagcctcagacagctcaggggagccgccgcagaaa
aatgataacaacggccctctgccagagactcctaagcgggctgagccagcctcccacaaa
ggtgccgacgataccgatcagcaaagaacttccgggccacccccacgccagaatccccca
ggcgactccctttcccctgatgacacctccccagcgccccaagccaatgcaacagggacc
gcagccctgaagaccccagataccgatggcccgtcgtctccagccaagccccagggcccg
cgagccagacccctctccaagaaagacaagaagcaggagcacatcaagaggcagctgatg
accaactttatcctgggctccttcgacgacaactcctccgatgaggaccccggtgccggc
ttgttccgagagtctccccggaagggcagccgggccagcctggggactctgtctctggag
gctgctcacactgcaggcgagccggagaaccccgtccccaccataagacccagcatgtcc
ggactccacctggtgaagaagggccgagaactaaagaaggtggacctgcacagagacttt
accgtggcctccccggctgagtttgtcacgcgcttcgggggggatcgggtcattgagaag
gtgctcatcgccaacaacggcatcgccgccgtgaagtgcatgcgctccatccgcaggtgg
gcctatgagatgttccgcaacgagcgggccatccggtttgttgtcatggtgaccccagag
gacctgaaggccaatgcagagtatatcaagatggcagatcagtacgtccctgtcccagga
gggcccaacaacaacaactatgccaacgtggagctggttgtggacattgccaagaggatc
cccgtgcaggcggtgtgggctggctggggccatgcttccgaaaaccccaaactcccggag
ctcctgtgcaagcatgagattgctttcttaggccctcccagtgaggccatgtgggccttg
ggagataagatcgcctccaccattgtggcccagacgctgcaggtcccaacactgccttgg
agtggaagtggtctgatgatagagtgggcggaagataatctgcaggaggggaaaaggatc
agtgtcccagaagacatttacaaccagggttgtgtgaaagatgtggatgagggcctagag
gtggcagagaaaattggttttcccttgatgatcaaagcttctgaaggcggtggagggaaa
ggaatccggaaagcagagagtgctgaggacttcccaatccttttcagacaagtgcagagt
gagatcccgggctccccgatctttctcatgaagctggcccagcacgcccggcacctggag
gtccagatcctcgccgaccagtacgggaacgccgtgtctctgttcgggcgtgactgctcc
atccagcggcggcatcagaagatcatcgaggaggcaccggccaccatcgccacaccggct
gtgttcgagttcatggagcagtgtgccgtccgcctggccaagaccgtgggctacgtgagc
gcggggacggtggaatacctctacagccaggatggcagcttccactttctggagctgaat
ccccgcctgcaggtggagcacccgtgcacggaaatgatcgccgacgtcaacctgccggcc
gcccagctacagatcgccatgggggtgccgttgcaccggctgaaggatatccggcttctg
tacggagagtcgccgtggggggtgacacccatttcatttgaaactccttccaaccctccg
ctcgcccgaggccatgtcatcgcggccagaatcaccagcgagaacccagatgaggggttt
aagccaagctccggaacggttcaggaactgaatttccgcagcaacaagaatgtgtggggt
tatttcagcgtggctgctactggcggcttacacgaatttgcggattcccagttcgggcac
tgcttctcctggggagagaaccgggaagaggccatttcgaacatggtggtggctttgaag
gagctgtccatccggggcgacttcaggaccaccgtggagtatctcattaacctgctggag
accgagcgtttccagaacaatgacatcgacacagggtggttggatcacctcatcgctgag
aaagtgcaggctgagaagccagatatcatgcttggggtggtgtgtggagccttgaacgtg
gccgatgtgatgttcagaacctgcatgacggatttcttacactcgctggaaaggggccag
gtccttcctgccgcttctctgctgaacatcgtggatgtggaattaatttatgatggcgtt
aagtacattctcaaggtggcccggcaatctctgaccatgttcgtcctcatcatgaacggc
tgtcacatcgagatcgacgcccaccggctgaatgacggcgggttactgctgtcctacaat
ggcaacagctataccacctacatgaaagaagaggttgacagttaccgtgttaccattggc
aacaagacctgtgtgtttgagaaggagaacgatcccacggtcctgaggtccccttcggcc
gggaagctaatacagtacacggtggaggacgggggccacgtcgaggctgggagcagctac
gcggagatggaggtgatgaagatgatcatgaccctgaacgtgcaggaaagcggccgggtg
aagtacatcaagcgcgcgggggccgtgctggaagcaggctgtgtggtggccaagctggag
ctcgatgacccttccaaagtgcgcccggccgagccattcacaggagagctcccttcccag
caaactctgcccatcgtcggagagaaactacaccaggttttccacaacgtcctggaaaac
ctgaccaacgtcatgaatggctactgcctgccagagcccatttttagcaccaagctgaag
gagtgggtgcagaaactcatgacgaccctgcggcacccgtccctgccgctgctggagctg
caggagatcatgaccagcgtgtcgggccgcatccccgcccccgtggagaagtcggtccgc
agggtgatggctcagtatgccagcaacatcacctcggtgctgtgccagttccccagccag
cagatagccactatcctggactgccacgcggccaccctgcagcggaaggctgaccgggag
gtgttcttcatgaacacccagagcatcgtgcagctggtccagaggtaccgcagcgggacc
cgcggctacatgaaggcagtggtgttggatctcctgagaagatatttacgcgtggaacac
catttccaacaagctcactacgacaagtgtgtgatcaacctcagggagcagctgaagcca
aacatgtcccaggtgctggactgcatcttttcccacgcgcaggtggccaagaagaaccag
ctggtgatcatgttgatcgatgagctctgtggcccagacccttccctgtcggaagagctg
acctccatcctcaatgagctcactcagctgagcaaaagcgagcattgcaaagtggccctc
agagcgagacagatcctgatcgcctcccacctcccgtcctacgagctgaggcacaaccag
gtggagtccattttcctgtccgccatcgacatgtatggccaccagttctgcccggaaaac
ctcaagaaattaatactgtcagagacgaccatattcgacgtcctgcccactttcttctac
cacactaacaaggtcgtttgcatggcgtccctggaggtttacgtgcgaaggggctacatc
gcctatgagttaaacagcttgcagcaccggcagctcccagatggcacctgcgtggtagaa
ttccagttcatgctgccctcctcccacccaaaccggatggccgtgcccatcagtgtcacc
aaccccgacctgctgaggcacagcaccgagctcttcatggacagcggctttgccccactg
tgtcagcggatgggggccatggttgccttcaggagatttgaggacttcacaagaaacttc
gacgaagtcatctcctgctttgccaacgtgcccagggaaatccccctcttcaggaaggcc
tgcactcccttgtactctgaagaagagaacaagagcctcagagaggagccaatccacatc
ctgaatgtggccatccagtacgcggaccacctggaagatgaggagctggtgccgattttc
cggacgttcgtacagtccaagaaaaacatccttgtggaatatggactccgaagaatcaca
ttcctgattgcccaagagaaagaatttccgaagtttttcacattcagagcaagagatgag
tttgcagaagatcgcatttaccgtcacctggaacccgccctggccttccagctggagctc
agccggatgcgcagcttcgatctgaccgccgtgccctgcgccaaccacaagatgcacctg
tacctgggcgccgccaaagtgaaagaaggcgcggaggtgacagaccacagattcttcatc
cgcgccatcatcaggcactcggacctcattacgaaggaagcctcctttgagtacctgcag
aacgagggtgagcgtctgctcctggaagccatggatgagctggaggtggcgttcaacaac
accagtgtgcgcaccgactgcaaccacatcttcctgaacttcgtgcccaccgtcatcatg
gaccccttcaagatcgaggagtccgtgcgttccatggttatgcgctacggcagccggctg
tggaaactccgcgtgctgcaggctgaggtcaagatcaacatccgccagaccaccaccggc
agtgctgttcccatccgcctgttcatcaccaacgaatcgggctactacctggacatcagc
ctctacaaagaagtcaccgaccccagatctggaaacatcatgtttcactcctttggcaac
aaacagggcccccagcacgggatgctgatcaacactccctacgtcaccaaggatctgctt
caggccaagcgattccaggcccagtccctgggcaccacctacgtgtacgacttcccggag
atgttcaggcaggctctccttaaactgtggggctccacggacaactaccccaaagacatc
ctgacatacactgagctcgtgctggaccctcagagccagctggtggagatgaaccgcctc
cctggaggaaatgaggtgggcatggtggccttcaagatgaggtttaagacccgagagtat
ccagaagggcgggacgcgatcgtcatcagcaatgacatcaccttccgcattggatccttc
ggcctgggagaagaccttttgtatctgcgtgcgtctgagatggcccgggcagagggtatc
cccaaaatctacctcgcagccaacagcggggcctgtatcggccttgcagaggagatcaag
cacatgttccaggtggcttgggtggacccaggagacccctacaaaggctttaaatacctg
tacctgacgcctcaagactacaccagaatcagctccctaaactctgtccgttgtaaacac
atcgaggaagagggagagtccaggtatgtcatcacggatatcgtcgggaaggaccgtggc
ctgggcgtggagaacctcaagggctcgggcatgattgcaggggagtcctccctagcttac
gaagagatcgtcaccatcagtatggtgacctgccgagcccttgggatcggggcctacttg
gtgaggctgggccagcgagtgatccaggtggaaaattcgcacatcatcctgacgggagcc
agcgctctcaacaaggtcctgggcagagaggtttacacctccaacaaccagctgggcggc
gtgcagatcatgcatcacaacggcgtctcccacgtcactgtgccagacgacttcgagggc
gtgtacaccatcctggagtggctgtcctatatgccaaaggataatcgcagtccagtcccc
atcaccacaccctcggaccccattgaccgagaaattgaattcttcccgtccagggctccc
tacgacccccggtggctgcttgcaggacggcctcacccaactctgaagggatcctggcag
agtggattctttgaccacggcagtttcaaggaaatcatggcaccttgggcccagacggtg
gtgacaggaagagcgaggctaggggggatccctgttggagtgatcgccgtggagacgcgg
accgtggaggtggtagtgcctgcagaccctgccaacctggattccgaggccaagataatc
cagcaggcgggccaggtgtggttcccagactcagcctacaagacggcccaggccatcagc
gatttcaaccgagagggattgcccctgatagtctttgccaactggagggggttctccggt
ggcatgaaagacatgtacgaccaggtgctaaagtttggagcctacatcgtggacagcctc
aggcagtacaaacagcccgtcctgatctatatcccaccccacggggaactccgggggggc
tcctgggtggtcgtggactcctccatcaaccccctgtacatagaaacgtacgcagacaag
gagagcagggcgagcattctggagccggagggaacagtggagattaagttccgaaagaaa
gatctgataaagaccatgaggaggatcgacccagtttataagaagctcgtggaacagcta
ggagtgtccgagctcgccgataaggaccgcaaggacctggagggccagctgaaggcccgg
gaggacctgctcctgcccatctaccaccaggtggcggtgctgttcgctgacctccacgac
agggcctacggcatgctggagaagggtgtcgtctctgacatcgtggagtggaagacctca
cgcgccttcctgtactggcgtctgcgccgcctcctgctggaggaccaggtcaagcaggag
atactgcaggccagcagtgagctgagccacgtgcacatccagtccatgctgcgtcggtgg
ttcgtggagacggagggggccgtcaaggcctacctgtgggataacaaccagatggtggta
aagtggctggaacagcactggcagggcgggggcggcctgcgttccaccatccgcgagaac
atcaagtgtttgaagcgcgactccgtcctcaaggccatcagacgcctggttcaagagaac
cctgacgtggccgtggactgcatcgtgtacctgagccagcacattagctcagcagagcgg
gccgaagtcattcacctcctgtccaccatggacagcccagcctccacctga
DBGET
integrated database retrieval system
